Time-resolved fluorometry: an overview of the labels and core technologies for drug screening applications

Zwischenmolekulare Energiewanderung und Fluoreszenz

1948 • 7,839 citations

Enzyme-linked immunosorbent assay (ELISA) quantitative assay of immunoglobulin G

1971 • 3,630 citations

IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MAN

1960 • 2,983 citations

Europium as a label in time-resolved immunofluorometric assays

1984 • 865 citations

INSULIN-I131 METABOLISM IN HUMAN SUBJECTS: DEMONSTRATION OF INSULIN BINDING GLOBULIN IN THE CIRCULATION OF INSULIN TREATED SUBJECTS 1

1956 • 835 citations

Fluoroimmunoassay: present status and key problems.

1979 • 432 citations

Rare earth cryptates and homogeneous fluoroimmunoassays with human sera

1993 • 381 citations

Enhanced Dissociation of HLA-DR-Bound Peptides in the Presence of HLA-DM

1996 • 327 citations

Optical microscopic observation of single small molecules

1976 • 279 citations

Luminescent Polyaminocarboxylate Chelates of Terbium and Europium: The Effect of Chelate Structure

1995 • 277 citations

Applications of Fluorescence in Immunoassays

1992 • 260 citations

Scintillation proximity assay

1989 • 221 citations

Fluorescent excitation transfer immunoassay. A general method for determination of antigens.

1976 • 207 citations

FLIPR: A New Instrument for Accurate, High Throughput Optical Screening

1996 • 197 citations

Development of Luminescent Europium(III) and Terbium(III) chelates of 2,2′:6′,2″‐ terpyridine derivatives for protein labelling

1993 • 192 citations

Time-resolved detection of lanthanide luminescence for ultrasensitive bioanalytical assays

1995 • 178 citations

BASIC PRINCIPLES AND THEORY

1974 • 165 citations

Time‐resolved fluorescence imaging of europium chelate label in immunohistochemistry and in situ hybridization

1992 • 154 citations

Quantification of the antigen-antibody reaction by the polarization of fluorescence

1961 • 146 citations

Lanthanides as probes for time-resolved fluorometric immunoassays

1988 • 144 citations

Luminescent lanthanide chelates—a way to more sensitive diagnostic methods

1995 • 141 citations

Synthesis of Europium(III) Chelates Suitable for Labeling of Bioactive Molecules

1994 • 141 citations

Nonisotopic DNA Probe Techniques

1992 • 137 citations

Fluorescent tandem phycobiliprotein conjugates. Emission wavelength shifting by energy transfer

1983 • 133 citations

Time-resolved detection of energy transfer: Theory and application to immunoassays

1988 • 116 citations

Time-resolved fluorometric assay for natural killer activity using target cells labelled with a fluorescence enhancing ligand

1996 • 115 citations

Simultaneous Quadruple-Label Fluorometric Immunoassay of Thyroid-Stimulating Hormone, 17 α-Hydroxyprogesterone, Immunoreactive Trypsin, and Creatine Kinase MM Isoenzyme in Dried Blood Spots

1992 • 109 citations

The synthesis and use of activated N-benzyl derivatives of diethylenetriaminetetraacetic acids: Alternative reagents for labeling of antibodies with metal ions

1989 • 101 citations

One-step all-in-one dry reagent immunoassays with fluorescent europium chelate label and time-resolved fluorometry

1996 • 75 citations

Lanthanides as probes for time-resolved fluorometric immunoassays

1988 • 63 citations

Measurement of the Protein Tyrosine Kinase Activity of c-src Using Time-Resolved Fluorometry of Europium Chelates

1996 • 59 citations

Synthesis and Luminescence of Novel Eu^III Complexing Agents and Labels with 4‐(Phenylethynyl)pyridine Subunits

1996 • 56 citations

Europium chelate labels in time-resolved fluorescence immunoassays and DNA hybridization assays

1990 • 55 citations

The Influence of Phosphoroscope Design on the Measured Phosphorescence Intensity in Phosphorimetry.

1966 • 47 citations

Fluorescence Polarization Assays for the Detection of Proteases and Their Inhibitors

1996 • 46 citations

Homogeneous time-resolved fluoroimmunoassay of thyroxin in serum.

1988 • 44 citations

Measurement of estrone-3-glucuronide in urine by rapid, homogeneous time-resolved fluoroimmunoassay.

1989 • 41 citations

Development of instrumentation and fluorochromes for automated multiparameter analysis of cells.

1977 • 37 citations

Near-infrared fluorogenic labels: new approach to an old problem

1991 • 32 citations

Novel Thiazole‐Containing Complexing Agents and Luminescence of Their Europum(III) and Terbium(III) Chelates

1996 • 26 citations

A new homogeneous identification method for DNA

1994 • 23 citations

Nonisotopic Receptor Assay for Benzodiazepine Drugs Using Time-Resolved Fluorometry

1995 • 21 citations

Fluorescence lifetime filtering

1989 • 15 citations

Time-resolved europium fluorescence in enzyme activity measurements: a sensitive protease assay.

1983 • 15 citations

The 384-Well Plate: Pros and Cons

1996 • 11 citations

New complexing agents for labeling of proteins with metals.

1990 • 4 citations