Bending-incompetent variants of Flp recombinase mediate strand transfer in half-site recombinations: role of DNA bending in recombination

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Empirical estimation of protein-induced DNA bending angles: applications to λ site-specific recombination complexes

1988 • 672 citations

Functional replacement of a protein-induced bend in a DNA recombination site

1989 • 259 citations

DNA Looping Generated by DNA Bending Protein IHF and the Two Domains of Lambda Integrase

1989 • 176 citations

The FLP recombinase of the yeast 2-micron plasmid: characterization of its recombination site.

1985 • 157 citations

Why bend DNA?

1990 • 134 citations

Step-arrest mutants of FLP recombinase: implications for the catalytic mechanism of DNA recombination.

1988 • 112 citations

The γδ resolvase induces an unusual DNA structure at the recombinational crossover point

1987 • 107 citations

Phasing of protein-induced DNA bends in a recombination complex

1989 • 98 citations

DNA-protein complexes during attachment-site synapsis in Mu DNA transposition.

1991 • 90 citations

Two-micrometer circle site-specific recombination: the minimal substrate and the possible role of flanking sequences.

1985 • 88 citations

Cooperativity mutants of the γδ resolvase identify an essential interdimer interaction

1990 • 81 citations

Yeast plasmids resembling 2 micron DNA: regional similarities and diversities at the molecular level

1987 • 74 citations

Identification of the active site tyrosine of Flp recombinase. Possible relevance of its location to the mechanism of recombination.

1990 • 73 citations

Holliday junctions in FLP recombination: resolution by step-arrest mutants of FLP protein.

1988 • 69 citations

Functional analysis of Arg-308 mutants of Flp recombinase. Possible role of Arg-308 in coupling substrate binding to catalysis.

1990 • 69 citations

Half-att site substrates reveal the homology independence and minimal protein requirements for productive synapsis in λ excisive recombination

1989 • 66 citations

Determination of DNA sequences essential for FLP-mediated recombination by a novel method.

1985 • 63 citations

Mutations in the 2-microns circle site-specific recombinase that abolish recombination without affecting substrate recognition.

1987 • 63 citations

Isolation of intermediates in the binding of the FLP recombinase of the yeast plasmid 2-micron circle to its target sequence

1987 • 61 citations

Protein-based asymmetry and protein-protein interactions in FLP recombinase-mediated site-specific recombination.

1990 • 59 citations

Holliday intermediates and reaction by-products in FLP protein-promoted site-specific recombination.

1988 • 52 citations

Identification of the DNA-binding domain of the FLP recombinase

1991 • 49 citations

FLP Recombinase of the 2 μm circle plasmid of Saccharomyces cerevisiae bends its DNA target

1989 • 49 citations

FLP protein of 2 μ circle plasmid of yeast induces multiple bends in the FLP recognition target site

1990 • 48 citations

Synapsis, strand scission, and strand exchange induced by the FLP recombinase: analysis with half-FRT sites.

1991 • 42 citations

Half-site recombinations mediated by yeast site-specific recombinases Flp and R

1992 • 38 citations

Substrate recognition by the 2 micron circle site-specific recombinase: effect of mutations within the symmetry elements of the minimal substrate.

1986 • 27 citations

Synaptic intermediates promoted by the FLP recombinase

1990 • 24 citations

Domain of a yeast site-specific recombinase (Flp) that recognizes its target site.

1991 • 20 citations

Tyr60 variants of Flp recombinase generate conformationally altered protein-DNA complexes

1991 • 16 citations

Deleted Work

1955 • 0 citations