Effects of lysomotropic agents and of microfilament- and microtubule-disrupting drugs on the activation of casein-gene expression by prolactin in the mammary gland

Lysosomotropic agents

1974 • 1,887 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Surface Modulation in Cell Recognition and Cell Growth

1976 • 1,062 citations

Transmembrane control of the receptors on normal and tumor cells

1976 • 951 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

A cytoskeletal structure with associated polyribosomes obtained from HeLa cells

1977 • 530 citations

Collection of insulin, EGF and α2-Macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization

1978 • 372 citations

Regulation of receptor concentration by homologous hormone. Effect of human growth hormone on its receptor in IM-9 lymphocytes.

1976 • 364 citations

Epidermal growth factor. Relationship between receptor regulation and mitogenesis in 3T3 cells.

1978 • 324 citations

Thyrotropin-releasing hormone regulates the number of its own receptors in the GH3 strain of pituitary cells in culture

1975 • 300 citations

Amines inhibit the clustering of α2-macroglobulin and EGF on the fibroblast cell surface

1979 • 237 citations

Regulation of luteinizing hormone receptors in testicular interstitial cells by gonadotropin

1976 • 225 citations

Gonadotropin-induced loss of hormone receptors and desensitization of adenylate cyclase in the ovary.

1976 • 208 citations

Spectrophotometric Studies of the Interaction of Chloroquine with Deoxyribonucleic Acid

1965 • 207 citations

Intracellular polypeptide hormone receptors. The demonstration of specific binding sites for insulin and human growth hormone in Golgi fractions isolated from the liver of female rats.

1978 • 196 citations

The fate of insulin bound to adipocytes. Evidence for compartmentalization and processing.

1978 • 189 citations

Prolactin–progesterone antagonism in self regulation of prolactin receptors in the mammary gland

1977 • 180 citations

Ammonia inhibition of protein degradation in isolated rat hepatocytes

1976 • 172 citations

Degradation of receptor-bound human choriogonadotropin by murine Leydig tumor cells.

1978 • 165 citations

Inactivation of lysosomal function in normal cultured human fibroblasts by chloroquine

1973 • 153 citations

The participation of α-actinin in the capping of cell membrane components

1979 • 152 citations

Evolution of Prolactin Receptors in Rabbit Mammary Gland During Pregnancy and Lactation

1977 • 150 citations

Entry of Insulin Into Human Cultured Lymphocytes: Electron Microscope Autoradiographic Analysis

1978 • 135 citations

Prolactin induction of casein mRNA in organ culture. A model system for studying peptide hormone regulation of gene expression.

1978 • 126 citations

Blockade of Prolactin Action by an Antiserum to Its Receptors

1976 • 123 citations

67th ANNUAL MEETING OF THE ENDOCRINE SOCIETY

1985 • 123 citations

Mechanism of corticotropin action in rat adrenal cells I. The effects of inhibitors of protein synthesis and of microfilament formation on corticosterone synthesis

1978 • 122 citations

Detection of Endogenous Immunoreactive Prolactin in Rat Mammary Epithelial Cells During Lactation1¹

1976 • 118 citations

Internalisation of gonadotrophin–receptor complex in ovarian luteal cells

1978 • 114 citations

Cell surface action of thrombin is sufficient to initiate division of chick cells

1978 • 112 citations

Protein degradation in isolated rat hepatocytes is inhibited by ammonia

1975 • 99 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors

1978 • 87 citations

Role of prolactin and glucocorticoids in the expression of casein genes in rabbit mammary gland organ culture. Quantification of casein mRNA

1978 • 83 citations

Studies on the regulation of ornithine decar☐ylase activity by the microtubules: The effect of colchicine and vinblastine

1976 • 75 citations

AUTORADIOGRAPHIC LOCALIZATION OF THE BINDING OF 125I-LABELLED PROLACTIN TO RAT TISSUES IN VITRO

1977 • 71 citations

Effects of Prolactin and Progesterone on Expression of Casein Genes. Titration of Casein mRNA by Hybridization with Complementary DNA

1976 • 70 citations

Antibodies to denatured deoxyribonucleic acid in lupus erythematosus serum. V. Mechanism of DNA-anti-DNA inhibition by chloroquine

1963 • 67 citations

Does Insulin Need a Second Messenger?

1977 • 66 citations

Receptor regulation and target cell responses: Studies in the ovarian luteal cell

1978 • 64 citations

Insulin binding sites on rat liver nuclear membranes: Biochemical and immunofluorescent studies

1978 • 63 citations

Cell surface receptors for insulin and human growth hormone. Effect of microtubule and microfilament modifiers.

1976 • 63 citations

Intracellular Prolactin in Rat Corpus Luteum and Adrenal Cortex

1978 • 63 citations

Insulin receptors and the site of action of insulin

1978 • 62 citations

Regulation of casein synthesis in the rabbit mammary gland

1975 • 61 citations

Regulation of testicular LH receptors by homologous hormone: In vitro studies on receptor occupancy and receptor loss

1977 • 58 citations

Reversible suppression of lactation by colchicine

1974 • 56 citations

Intracellular uptake and catabolism of lutropin by testicular tissue in vivo

1977 • 52 citations

Peptide map analyses of murine Ia antigens of the I–E subregion using HPLC

1979 • 50 citations

The supression of milk fat globule secretion by colchicine: an effect coupled to inhibition of exocytosis

1977 • 49 citations

In vivo regulation of cell surface and intracellular insulin binding sites by insulin.

1978 • 47 citations

Early effects of prolactin on lactating rabbit mammary gland

1978 • 46 citations

Effects of Glucocorticoids on Casein Gene Expression in the Rabbit

1977 • 46 citations

LACTOGENIC ACTIVITY IN THE SERUM OF RABBITS DURING PREGNANCY AND EARLY LACTATION

1977 • 44 citations

Effects of colchicine on ultrastructure of the lactating mammary cell: Membrane involvement and stress on the Golgi apparatus

1978 • 42 citations

The effect of di-butyryl cAMP on enzymatic and metabolic changes in explants of rat mammary tissue

1974 • 42 citations

Mechanisms of Secretion: Effects of Colchicine and Vincristine on Composition and Flow of Milk in the Goat

1976 • 39 citations

Demonstration of a direct effect of inhibitors of the degradation of receptor-bound human choriogonadotropin on the steroidogenic pathway

1978 • 36 citations

Polypeptide Hormones: What Are They Doing in Cells?

1978 • 35 citations

Evidence for Androgen-Dependent Intracellular Binding of Prolactin in Rat Ventral Prostate Gland¹

1977 • 35 citations

Does insulin need a second messenger?

1977 • 30 citations

Drugs that disrupt microtubuli do not inhibit lymphocyte activation

1976 • 28 citations

Colchicine inhibits the accumulation of messenger RNA for a brain-specific protein in rat glial cells

1978 • 26 citations

Binding and internalization of ¹²⁵I thrombin in chick embryo fibroblasts: Possible role in mitogenesis

1978 • 25 citations

Inhibition of mammary gland lactose secretion by colchicine and vincristine

1978 • 22 citations

Role of prolactin in the expression of casein genes in the virgin rabbit

1979 • 21 citations

LACK OF MITOTIC EFFECTS OF INSULIN DURING SYNTHESIS OF CASEIN INDUCED BY PROLACTIN IN PSEUDOPREGNANT RABBIT MAMMARY GLAND ORGAN CULTURES

1977 • 17 citations