A longitudinal study on IL-2, sIL-2R, IL-4 and IFN-γ in multiple sclerosis CSF and serum

PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS

1965 • 1,402 citations

Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values

1977 • 867 citations

Two types of mouse helper T-cell clone

1987 • 813 citations

Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values

1977 • 779 citations

Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.

1988 • 389 citations

Criteria for the clinical diagnosis of multiple sclerosis

1976 • 376 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Further notes on disability evaluation in multiple sclerosis, with scale modifications

1965 • 310 citations

In Vivo Activated T Lymphocytes in the Peripheral Blood and Cerebrospinal Fluid of Patients with Multiple Sclerosis

1985 • 307 citations

Selective Loss of the Suppressor-Inducer T-Cell Subset in Progressive Multiple Sclerosis

1987 • 240 citations

Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities.

1989 • 239 citations

MS: a CNS and systematic autoimmune disease

1989 • 231 citations

A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex

1989 • 219 citations

Improved detection of oligoclonal IgG in cerebrospinal fluid by isoelectric focusing in agarose, double-antibody peroxidase labeling, and avidin-biotin amplification.

1984 • 199 citations

Production of lymphokine mRNA by CD45R+ and CD45R- helper T cells from human peripheral blood and by human CD4+ T cell clones.

1989 • 169 citations

The Diagnosis of Multiple Sclerosis

1985 • 160 citations

T-cell receptor V alpha and C alpha alleles associated with multiple and myasthenia gravis.

1989 • 158 citations

Multiple Sclerosis Research

2013 • 144 citations

The Role of IL4 and IL5: Characterization of a Distinct Helper T Cell Subset that makes IL4 and IL5 (Th2) and Requires Priming before Induction of Lymphokine Secretion

1988 • 123 citations

The role of interleukin 2 in autoimmunity

1989 • 89 citations

Immune activation in multiple sclerosis: study of IL-2, sIL-2R, and γ-IFN levels in serum and cerebrospinal fluid

1989 • 88 citations

MS: a localized immune disease of the central nervous system

1989 • 72 citations

Correlation of immunological studies and disease progression in chronic progressive multiple sclerosis

1989 • 63 citations

Interleukin‐2 levels in serum and cerebrospinal fluid of multiple sclerosis patients

1988 • 60 citations

Elevated Levels of Soluble Interleukin-2 Receptors in Multiple Sclerosis

1988 • 56 citations

Differential Growth Requirements and Effector Functions of α/β and γ/δ Human T Cells

1989 • 22 citations

CD45R as a primary signal transducer stimulating IL-2 and IL-2R mRNA synthesis by CD3-4-8- thymocytes.

1989 • 22 citations

Serial studies of serum interleukin-2 in chronic progressive multiple sclerosis patients: occurrence of ‘bursts’ and effect of cyclosporine

1990 • 21 citations

Detection of IgG oligoclonal bands in unconcentrated CSF by means of agarose isoelectric focusing, double immunofixation peroxidase staining and avidin-biotin amplification

1985 • 21 citations

Trends in Neuroimmunology

1990 • 4 citations