Polymorphic MHC ancestral haplotypes affect the activity of tumour necrosis factor-alpha

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

1990 • 643 citations

Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production.

1991 • 553 citations

Ancestral haplotypes: conserved population MHC haplotypes

1992 • 255 citations

A New Cluster of Genes Within the Human Major Histocompatibility Complex

1989 • 247 citations

Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region.

1989 • 183 citations

Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus.

1989 • 164 citations

Association between HLA‐DR2 and Production of Tumour Necrosis Factor α and Interleukin 1 by Mononuclear Cells Activated by Lipopolysaccharide

1988 • 144 citations

An approach to the localization of the susceptibility genes for generalized myasthenia gravis by mapping recombinant ancestral haplotypes

1992 • 133 citations

Tumor necrosis factor α in autoimmunity: pretty girl or old witch?

1992 • 128 citations

Central MHC genes, IgA deficiency and autoimmune disease

1990 • 94 citations

Some disease-associated ancestral haplotypes carry a polymorphism of TNF

1989 • 79 citations

Major histocompatibility complex genes influence the outcome of HIV infection

1990 • 76 citations

Major histocompatibility complex (MHC) complement deficiency, ancestral haplotypes and systemic lupus erythematosus (SLE): C4 deficiency explains some but not all of the influence of the MHC.

1991 • 64 citations

Haplotypic polymorphisms of the TNFB gene

1991 • 55 citations

1 Overview: the major histocompatibility complex and insulin dependent diabetes mellitus

1991 • 28 citations

Cytotoxic lymphokines produced by cloned human cytotoxic T lymphocytes. I. Cytotoxins produced by antigen-specific and natural killer-like CTL are dissimilar to classical lymphotoxins.

1985 • 20 citations

5 Studies of MHC haplotypes by pulsed field gel electrophoresis

1991 • 11 citations