Gender-related differences in ventricular myocyte repolarization in the guinea pig

An analysis of the time-relations of electrocardiograms

1920 • 3,889 citations

A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes.

1994 • 1,549 citations

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.

1990 • 1,467 citations

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

1993 • 843 citations

Cellular Basis for the Electrocardiographic J Wave

1996 • 801 citations

Sex differences in the evolution of the electrocardiographic QT interval with age.

1992 • 634 citations

Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea‐pig heart.

1984 • 560 citations

Inactivation of calcium channels in mammalian heart cells: joint dependence on membrane potential and intracellular calcium.

1985 • 477 citations

Two Components of the Delayed Rectifier K ⁺ Current in Ventricular Myocytes of the Guinea Pig Type

1995 • 417 citations

Sex Hormones Prolong the QT Interval and Downregulate Potassium Channel Expression in the Rabbit Heart

1996 • 368 citations

Electrical heterogeneity within the ventricular wall

2001 • 330 citations

Voltage‐dependent inactivation of inward‐rectifying single‐channel currents in the guinea‐pig heart cell membrane.

1984 • 271 citations

Sex differences on the electrocardiographic pattern of cardiac repolarization: Possible role of testosterone

2000 • 251 citations

Two types of calcium channels in guinea pig ventricular myocytes.

1986 • 230 citations

Ovariectomy and 17β-estradiol modulate the levels of Alzheimer’s amyloid β peptides in brain

2000 • 221 citations

Gender difference in the cycle length-dependent QT and potassium currents in rabbits.

1998 • 208 citations

Gender and the relationship between ventricular repolarization and cardiac cycle length during 24-h Holter recordings

1997 • 206 citations

Voltage‐dependent activation of the inward‐rectifier potassium channel in the ventricular cell membrane of guinea‐pig heart.

1985 • 202 citations

Remodeling of cardiomyocyte ion channels in human atrial fibrillation

2003 • 191 citations

Sex, hormones, and repolarization

2002 • 189 citations

Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus.

1990 • 189 citations

A comparison of calcium currents in rat and guinea pig single ventricular cells.

1984 • 167 citations

Block of the Rapid Component of the Delayed Rectifier Potassium Current by the Prokinetic Agent Cisapride Underlies Drug-Related Lengthening of the QT Interval

1998 • 164 citations

Impact of Sex and Gonadal Steroids on Prolongation of Ventricular Repolarization and Arrhythmias Induced by I _K -Blocking Drugs

2001 • 139 citations

Ca ²⁺ Influx During the Cardiac Action Potential in Guinea Pig Ventricular Myocytes

1996 • 127 citations

QT interval-heart rate relation during exercise in normal men and women: Definition by linear regression analysis

1996 • 124 citations

Effects of gonadal steroids on ventricular repolarization and on the response to E4031.

1998 • 122 citations

Relation between reverse sodium-calcium exchange and sarcoplasmic reticulum calcium release in guinea pig ventricular cells.

1994 • 118 citations

Effects of gonadal steroids on gender-related differences in transmural dispersion of L-type calcium current

2002 • 109 citations

Increased Propensity of Women to Develop Torsades de Pointes During Complete Heart Block

1995 • 92 citations

Effects of quinidine on plateau currents of guinea-pig ventricular myocytes

1986 • 77 citations

Effects of estrogen on action potential and membrane currents in guinea pig ventricular myocytes

1999 • 75 citations

Effects of hormone replacement therapy on QT interval

1998 • 68 citations

Rate-dependence of antiarrhythmic and proarrhythmic properties of class I and class III antiarrhythmic drugs

1998 • 53 citations

Arrhythmias on ambulatory electrocardiographic monitoring in women without apparent heart disease

1984 • 48 citations

Secretion of Ovarian Inhibin and Its Physiologic Roles in the Regulation of Follicle-Stimulating Hormone Secretion during the Estrous Cycle of the Female Guinea Pig1

1999 • 47 citations

Maximal ascending and descending slopes of the T wave in men and women

1997 • 46 citations

Gender differences in the proarrhythmic potential of QT-prolonging drugs.

2002 • 30 citations

Electrophysiological aspects of changes in heart rate

1998 • 27 citations

Anti-adrenergic effect of adenosine on Na+–Ca2+exchange currentrecorded from guinea-pigventricular myocytes

2001 • 26 citations

Atrial fibrillation: are there gender differences?

2001 • 18 citations

Generating and influencing Torsades de Pointes - like polymorphic ventricular tachycardia in isolated guinea pig hearts

1998 • 18 citations

Effects of Long-Term Hormone Replacement Therapy on QT and Corrected QT Dispersion during Resting and Peak Exercise Electrocardiography in Post-Menopausal Women.

2002 • 14 citations

Effect of internal sodium and cellular calcium load on voltage-dependence of the Indo-1 transient in guinea-pig ventricular myocytes

1996 • 8 citations

Vitamin K Modulates Cardiac Action Potential by Blocking Sodium and Potassium Ion Channels

2000 • 5 citations