Biochemical studies on the mechanisms by which dietary antioxidants suppress mutagenic activity

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

1973 • 825 citations

Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene

1975 • 785 citations

The Glutathione S ‐Transferases: A Group of Multifunctional Detoxification Proteins

1978 • 686 citations

Biological Reactive Intermediates

1977 • 597 citations

The Role of Glutathione and Glutathione S‐Transferases in Mercapturic Acid Biosynthesis

1969 • 577 citations

Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions

1971 • 570 citations

Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants.

1978 • 338 citations

Inhibition of Chemical Carcinogenesis

1978 • 321 citations

Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

1976 • 316 citations

Inhibitors of Chemical Carcinogenesis

1978 • 304 citations

Liver response tests. III. Liver enlargement and stimulation of microsomal processing enzyme activity

1965 • 211 citations

The effects of antioxidants on skin tumor initiation and aryl hydrocarbon hydroxylase.

1977 • 201 citations

On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene.

1958 • 180 citations

Liver microsomal expoxide hydrase. Solubilization, purification, and characterization.

1975 • 170 citations

Polynuclear aromatic hydrocarbons : chemistry, metabolism, and carcinogenesis

1976 • 162 citations

Relationship between the soluble glutathione-dependent delta 5-3-ketosteroid isomerase and the glutathione S-transferases of the liver.

1977 • 154 citations

Antimutagenic effects of 2(3)-tert-butyl-4-hydroxyanisole and of antimicrobial agents.

1978 • 132 citations

Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered.

1952 • 126 citations

Liver microsomal epoxide hydrase.

1977 • 99 citations

Effect of 2(3)-tert-butyl-4-hydroxyanisole administration on the activities of several hepatic microsomal and cytoplasmic enzymes in mice

1979 • 99 citations

The Host-Mediated Assay, a Practical Procedure for Evaluating Potential Mutagenic Agents in Mammals

1971 • 97 citations

Metabolic Fate in Animals of Hindered Phenolic Antioxidants in Relation to their Safety Evaluation and Antioxidant Function

1966 • 95 citations

K region benzo(α)pyrene-4,5-oxide is conjugated by homogeneous gluthathione S-transferases

1975 • 92 citations

Enhancement of liver microsome epoxide hydratase activity in rodents by treatment with 2(3)-tert-butyl-4-hydroxyanisole.

1978 • 83 citations

The glutathione S-transferases as a possible detoxification system of rat intestinal epithelium

1977 • 83 citations

Effects of Butylated Hydroxyanisole on the Metabolism of Benzo[a]pyrene by Mouse Liver Microsomes2

1977 • 78 citations

Effect of the antioxidant butylated hydroxytoluene (BHT) on the metabolism of the carcinogens N-2-fluorenylacetamide and N-hydroxy-N-2-fluorenylacetamide

1973 • 74 citations

Alterations in Microsomal Metabolism of Benzo [<italic>a</italic>] pyrene in Mice Fed Butylated Hydroxyanisole<xref ref-type="fn" rid="fn2">2</xref>

1975 • 72 citations

Trans-stilbene oxide: a selective inducer of rat liver epoxide hydratase.

1978 • 69 citations

Ethoxyquin as an inducer and inhibitor of phenobarbital-type cytochrome P-450 in rat liver microsomes

1977 • 47 citations

Epoxide hydratase as a modifier of biotransformation and biological activity

1977 • 42 citations

Hepatic and extrahepatic metabolism of ¹⁴ C-styrene oxide

1976 • 39 citations

Epoxide Hydratase: Purification to Apparent Homogeneity as a Specific Probe for the Relative Importance of Epoxides among Other Reactive Metabolites

1977 • 23 citations