Murine models of autoimmune diabetes: Nonspecific cytotoxic lymphocytes derived from pancreatic islets in the presence of IL-2

A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 • 1,787 citations

Type I Diabetes Mellitus

1986 • 1,615 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1983 • 1,078 citations

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

1976 • 972 citations

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

1985 • 935 citations

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1987 • 576 citations

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

1982 • 531 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice.

1988 • 455 citations

The histopathology of the pancreas in Type I (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

1986 • 453 citations

CYCLOSPORIN INCREASES THE RATE AND LENGTH OF REMISSIONS IN INSULIN-DEPENDENT DIABETES OF RECENT ONSET

1986 • 443 citations

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases.

1985 • 387 citations

The spontaneously diabetic Wistar rat (the ?BB? rat)

1978 • 267 citations

Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon.

1985 • 249 citations

Lymphokine-activated killer cell activity

1987 • 235 citations

IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans.

1988 • 235 citations

Preventive Effect of Monoclonal Anti-L3T4 Antibody on Development of Diabetes in NOD Mice

1987 • 216 citations

Multiple immunological abnormalities in patients with Type 1 (insulin-dependent) diabetes mellitus

1987 • 205 citations

Immunologic Aspects of the Nonobese Diabetic (NOD) Mouse: Abnormalities of Cellular Immunity

1983 • 199 citations

Cytokines Cause Functional and Structural Damage to Isolated Islets of Langerhans

1985 • 180 citations

Antipancreatic Cellular Hypersensitivity in Diabetes Mellitus

1971 • 180 citations

Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells.

1986 • 156 citations

Passive Transfer of Diabetes in the BB/W Rat

1983 • 155 citations

“Cytoplasmic” Islet Cell Antibodies: Evidence That the Target Antigen Is a Sialoglycoconjugate

1985 • 116 citations

Multiple low-dose streptozotocin-induced diabetes in the mouse. Evidence for stimulation of a cytotoxic cellular immune response against an insulin-producing beta cell line.

1984 • 109 citations

Multiple mechanisms of lymphocyte-mediated killing

1988 • 90 citations

Spontaneous diabetes mellitus in the Bio-Breeding/Worcester rat. Evidence in vitro for natural killer cell lysis of islet cells.

1986 • 77 citations

Treatment With Anti-T-Lymphocyte Antibodies Prevents Induction of Insulitis in Mice Given Multiple Doses of Streptozocin

1987 • 62 citations

Genetic Analysis for Insulitis in NOD Mice

1985 • 56 citations

Specific Immunity to Streptozocin: Cellular Requirements for Induction of Lymphoproliferation

1988 • 53 citations

Loss of specificity in cytolytic T lymphocyte clones obtained by limit dilution culture of Ly-2+ T cells.

1984 • 52 citations

Alterations in lymphocyte subpopulations in type 1 (insulin-dependent) diabetes mellitus: exploration of possible mechanisms and relationships to autoimmune phenomena

1984 • 48 citations

Immunologic Studies on the Induction of Diabetes in Experimental Animals: Cellular Basis for the Induction of Diabetes by Streptozotocin

1984 • 48 citations

Isolation of T-Lymphocyte Lines with Specificity for Islet Cell Antigens from Spontaneously Diabetic (Insulin-dependent) Rats

1984 • 30 citations

64,000-Mr Autoantigen in Type I Diabetes: Evidence Against Its Surface Location on Human Islets

1987 • 30 citations

Maintenance of antigen specificity by human interleukin-2-dependent T cell lines. Use of antigen-presenting cells and OKT3 antibody in the absence of antigen.

1985 • 25 citations

T cell nature of some lymphokine‐activated killer (LAK) cells. Frequency analysis of LAK precursors within human T cell populations and clonal analysis of LAK effector cells

1986 • 24 citations

‘Supernatural’ killer cells

1985 • 22 citations

Helper-Inducer T-Lymphocytes Mediate Diabetes in EMC-Infected BALB/c By J Mice

1987 • 22 citations

T cell hybrids with specificity for islet cell antigens.

1986 • 19 citations

Degradation of specificity in cytolytic T lymphocyte clones: two broad specificity, H‐2‐independent recognition systems, one natural killer‐like, develop during culture, in addition to the clonally distributed antigen‐specific receptor

1985 • 10 citations

Expression of T cell antigen receptor and immunoglobulin genes in lymphoid organs visualized by in situ hybridization.

1987 • 9 citations

Human T-cell clones find ever wider application

1985 • 4 citations

Cloned human cytotoxic T lymphocytes develop anomalous killer cell function.

1986 • 3 citations