Expression of 25-Hydroxyvitamin D₃-24-Hydroxylase Activity in Caco-2 Cells, Anin VitroModel of Intestinal Vitamin D Catabolism*

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

Incorporation of 3H-uridine and 3H-uracil into RNA

1974 • 485 citations

The human colon carcinoma cell lines HT-29 and Caco-2: Two in vitro models for the study of intestinal differentiation

1986 • 470 citations

Target cell metabolism of 1,25-dihydroxyvitamin D3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation

1989 • 246 citations

Calcitroic acid, end product of renal metabolism of 1,25-dihydroxyvitamin D3 through the C-24 oxidation pathway

1989 • 245 citations

Regulation of the hydroxylation of 25-hydroxyvitamin D3 in vivo and in primary cultures of chick kidney cells.

1979 • 213 citations

25-Hydroxyvitamin D₃-24-hydroxylase. Subcellular location and properties

1974 • 195 citations

Common characteristics for Na+-dependent sugar transport in Caco-2 cells and human fetal colon

1987 • 194 citations

Metabolism of 1,25-dihydroxyvitamin D3

1984 • 160 citations

Rat intestinal 25-hydroxyvitamin D3- and 1alpha,25-dihydroxyvitamin D3-24-hydroxylase.

1978 • 136 citations

A novel cell line (Caco-2) for the study of intestinal lipoprotein synthesis.

1987 • 131 citations

Isolation and characterization of 1.alpha.-hydroxy-23-carboxytetranorvitamin D: a major metabolite of 1,25-dihydroxyvitamin D3

1979 • 129 citations

Vitamin D-dependent rickets type II. Defective induction of 25-hydroxyvitamin D3-24-hydroxylase by 1,25-dihydroxyvitamin D3 in cultured skin fibroblasts.

1985 • 82 citations

Side-chain hydroxylation of vitamin D3 and its physiological implications

1987 • 70 citations

Increased renal catabolism of 1,25-dihydroxyvitamin D3 in murine X-linked hypophosphatemic rickets.

1988 • 67 citations

Intestinal synthesis of 24-keto-1,25-dihydroxyvitamin D3. A metabolite formed in vivo with high affinity for the vitamin D cytosolic receptor.

1983 • 60 citations

1,25-Dihydroxyvitamin D3 induces 25-hydroxyvitamin D3-24-hydroxylase in a cultured monkey kidney cell line (LLC-MK2) apparently deficient in the high affinity receptor for the hormone.

1984 • 57 citations

1,25-Dihydroxyvitamin D3 receptors and functions in cultured pig kidney cells (LLC PK1). Regulation of 24,25-dihydroxyvitamin D3 production.

1982 • 55 citations

Isolation, identification, and metabolism of (23S,25R)-25-hydroxyvitamin D3 26,23-lactol. A biosynthetic precursor of (23S,25R)-25-hydroxyvitamin D3 26,23-lactone.

1984 • 53 citations

Isolation and identification of 1,25-dihydroxy-24-oxo-vitamin D3 and 1,23,25-trihydroxy-24-oxo-vitamin D3. New metabolites of vitamin D3 produced by a C-24 oxidation pathway of metabolism for 1,25-dihydroxyvitamin D3 present in intestine and kidney.

1983 • 49 citations

Ternary solvent mixtures for improved resolution of hydroxylated metabolites of vitamin D2 and vitamin D3 during high-performance liquid chromatography

1980 • 46 citations

Role of kidney tissue in the production of 25-hydroxyvitamin D3-26,23-lactone and 1 alpha, 25-dihydroxyvitamin D3-26,23-lactone.

1980 • 45 citations

Tissue-specific regulation of avian vitamin D-dependent calcium-binding protein 28-kDa mRNA by 1,25-dihydroxyvitamin D3.

1988 • 43 citations

Solubilization and reconstitution of kidney 25-hydroxyvitamin D3 1 α- and 24-hydroxylases from vitamin D-replete pigs

1989 • 34 citations

Chromatographic separation of 24(R),25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3-26,23-lactone using a cyano-bonded phase packing.

1983 • 32 citations

Biological activity assessment of 1α,25-dihydroxyvitamin D3-26,23-lactone in the rat

1984 • 30 citations

(23S)-1,23,25-Trihydroxycholecalciferol, an intestinal metabolite of 1,25-dihydroxycholecalciferol

1983 • 28 citations

In VitroMetabolism of 25-Hydroxyvitamin D₃by Human Trophoblastic Homogenates, Mitochondria, and Microsomes: Lack of Evidence for the Presence of 25- Hydroxyvitamin D₃-lα- and 24R-Hydroxylases*

1989 • 28 citations

Retinoic acid 5,6-epoxidase. Properties and biological significance.

1982 • 27 citations

1,25-Dihydroxyvitamin D3-inducible catabolism of vitamin D metabolites in mouse intestine

1990 • 24 citations

Side chain oxidation of 1,25-dihydroxyvitamin D3 in the rat: Effect of removal of the intestine

1977 • 22 citations

Effect of the X-Linked Hyp Mutation and Vitamin D Status on Induction of Renal 25-Hydroxyvitamin D₃-24-Hydroxylase*

1987 • 21 citations

Dominantly Inherited Osteogenesis Imperfecta in Man: An Examination of Collagen Biosynthesis

1975 • 21 citations

[15] A new pathway of 25-hydroxyvitamin D3 metabolism

1986 • 14 citations

Deleted Work

1955 • 0 citations