Limitations of current antimicrobial therapy in the immunosuppressed host: Looking at both sides of the coin

An Outbreak of Community-AcquiredPneumocystis cariniiPneumonia

1981 • 1,433 citations

Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a MutantEscherichia coli

1982 • 1,062 citations

Colonization resistance of the digestive tract in conventional and antibiotic-treated mice

1971 • 883 citations

Successful Chemoprophylaxis forPneumocystis cariniiPneumonitis

1977 • 688 citations

Human Cryptosporidiosis in Immunocompetent and Immunodeficient Persons

1983 • 682 citations

Acyclovir Prophylaxis of Herpes-Simplex-Virus Infections

1981 • 593 citations

The β-lactamases of Gram-negative bacteria and their rôle in resistance to β-lactam antibiotics

1976 • 539 citations

Nonbacterial Pneumonia After Allogeneic Marrow Transplantation: A Review of Ten Years' Experience

1982 • 537 citations

Current Clinical Topics in Infectious Diseases

1984 • 494 citations

Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. The EORTC international antimicrobial therapy project group.

1978 • 457 citations

Staphylococcus epidermidis: An Increasing Cause of Infection in Patients with Granulocytopenia

1982 • 456 citations

The Emergence of Methicillin-ResistantStaphylococcus aureusInfections in United States Hospitals

1982 • 432 citations

Infectious Complications of Human Bone Marrow Transplantation

1979 • 423 citations

Acyclovir Halts Progression of Herpes Zoster in Immunocompromised Patients

1983 • 416 citations

Mycobacterium avium-intracellulare: A Cause of Disseminated Life-Threatening Infection in Homosexuals and Drug Abusers

1982 • 385 citations

Varicella in children with cancer: Seventy-seven cases.

1975 • 380 citations

Three Antibiotic Regimens in the Treatment of Infection in Febrile Granulocytopenic Patients with Cancer

1978 • 372 citations

Fungal infections in patients with acute leukemia

1982 • 361 citations

Mucormycosis

1980 • 348 citations

Varicella in Children With Cancer: Seventy-Seven Case

1975 • 347 citations

Resistance to Antiviral Drugs of Herpes Simplex Virus Isolated from a Patient Treated with Acyclovir

1982 • 345 citations

Tuberculosis complicating neoplastic disease.A review of 201 cases

1974 • 339 citations

Intravenous Acyclovir to Treat Mucocutaneous Herpes Simplex Virus Infection After Marrow Transplantation

1982 • 333 citations

A Prospective Analysis of Interstitial Pneumonia and Opportunistic Viral Infection among Recipients of Allogeneic Bone Marrow Grafts

1977 • 329 citations

Infection Prevention in Acute Nonlymphocytic Leukemia

1975 • 327 citations

Protected Environments and Prophylactic Antibiotics

1973 • 323 citations

Prevention of Cytomegalovirus Infection by Cytomegalovirus Immune Globulin After Marrow Transplantation

1983 • 284 citations

Multicenter collaborative trial of intravenous acyclovir for treatment of mucocutaneous herpes simplex virus infection in the immunocompromised host

1982 • 263 citations

A prospective controlled investigation of prophylactic trimethoprim/sulfamethoxazole in hospitalized granulocytopenic patients

1979 • 247 citations

Infection prevention in granulocytopenic patients by selective decontamination of the digestive tract

1980 • 241 citations

Increased Pulmonary Superinfections in Cardiac-Transplant Patients Undergoing Primary Cytomegalovirus Infection

1978 • 241 citations

Histoplasmosis in immunosuppressed patients

1978 • 241 citations

Duration of empiric antibiotic therapy in granulocytopenic patients with cancer

1979 • 240 citations

Invasive Aspergillosis in Renal Transplant Recipients: Correlation with Corticosteroid Therapy

1983 • 235 citations

Coagulase-Negative Staphylococcal Bacteremia in Patients Receiving Immunosuppressive Therapy

1983 • 233 citations

Cytomegalovirus Immune Plasma in Bone Marrow Transplant Recipients

1982 • 231 citations

Impaired Antibody Response to Pneumococcal Vaccine after Treatment for Hodgkin's Disease

1978 • 216 citations

Prevention of Infection by Trimethoprim-Sulfamethoxazole Plus Amphotericin B in Patients with Acute Nonlymphocytic Leukaemia

1981 • 213 citations

Aspergillus Infections in Cancer Patients

1976 • 206 citations

Early Vidarabine Therapy to Control the Complications of Herpes Zoster in Immunosuppressed Patients

1982 • 205 citations

The Effect of Granulocyte Transfusions on the Incidence of Cytomegalovirus Infection After Allogeneic Marrow Transplantation

1982 • 202 citations

Mycobacteriosis in Patients With Malignant Disease

1976 • 192 citations

Improved prognosis for granulocytopenic patients with gram-negative bacteremia

1980 • 191 citations

Treatment of cytomegalovirus pneumonia with high-dose acyclovir

1982 • 188 citations

Colonization and Infection with Trichosporon Species in the Immunosuppressed Host

1983 • 180 citations

Oral antibiotic prophylaxis in patients with cancer: A double-blind randomized placebo-controlled trial

1983 • 171 citations

Herpesvirus infection of the esophagus and other visceral organs in adults

1979 • 170 citations

A controlled study of isolation and endogenous microbial suppression in acute myelocytic leukemia patients

1973 • 169 citations

Infections Complicating Multiple Myeloma and Chronic Lymphocytic Leukemia

1973 • 167 citations

Candida infections in patients with acute leukemia: Ineffectiveness of nystatin prophylaxis and relationship between oropharyngeal and systemic candidiasis

1982 • 159 citations

A Comparison of Trimethoprim-Sulfamethoxazole plus Nystatin with Gentamicin plus Nystatin in the Prevention of Infections in Acute Leukemia

1981 • 155 citations

Use of a Pseudomonas aeruginosa vaccine in patients with acute leukemia and cystic fibrosis

1975 • 151 citations

Aspergillosis of the nervous system

1982 • 151 citations

Lithium and leukocytosis

1971 • 149 citations

Bacteremias and Fungemias in Oncologic Patients With Central Venous Catheters

1982 • 140 citations

Infection Due to Corynebacterium Species in Marrow Transplant Patients

1979 • 134 citations

Treatment and Prevention of Intravascular Coagulation with Antiserum to Endotoxin

1973 • 133 citations

Approaching the controversies in antibacterial management of cancer patients

1984 • 130 citations

RANDOMIZED TRIAL OF PROTECTED ENVIRONMENT — PROPHYLACTIC ANTIBIOTICS IN 145 ADULTS WITH ACUTE LEUKEMIA

1978 • 130 citations

Bacteremia Due to Methicillin-Resistant Staphylococcus aureus

1982 • 122 citations

Synergistic effect on mortality in mice with murine cytomegalovirus and Pseudomonas aeruginosa, Staphylococcus aureus, or Candida albicans infections

1976 • 121 citations

Sepsis with a New Species of Corynebacterium

1976 • 120 citations

Increasing incidence of gram‐positive sepsis in cancer patients

1978 • 117 citations

Response of Patients with Hodgkin's Disease to Pneumococcal Vaccine

1979 • 116 citations

Methicillin-resistant staphylococcemia: bacteriological failure of treatment with cephalosporins.

1970 • 114 citations

Toxicity and Efficacy of Human Leukocyte Interferon for Treatment of Cytomegalovirus Pneumonia after Marrow Transplantation

1980 • 113 citations

Torulopsis glabrata infections in patients with cancer

1976 • 111 citations

Treatment of Cytomegalovirus Pneumonia after Marrow Transplant with Combined Vidarabine and Human Leukocyte Interferon

1982 • 111 citations

Selective Antimicrobial Modulation of the Intestinal Flora of Patients with Acute Nonlymphocytic Leukemia: A Double-Blind, Placebo-Controlled Study

1983 • 105 citations

Double-blind randomized study of prophylactic trimethoprim/sulfamethoxazole in granulocytopenic patients with hematologic malignancies

1983 • 105 citations

Antibiotic-resistant group JK bacteria in hospitals

1981 • 105 citations

Chemoprophylaxis of fungal infections

1984 • 102 citations

Effect of Adenine Arabinoside on Severe Herpesvirus hominis Infections in Man

1973 • 99 citations

CO-TRIMOXAZOLE FOR PREVENTION OF INFECTION IN ACUTE LEUKÆMIA

1978 • 98 citations

Role of serial microbiologic surveillance and clinical evaluation in the management of cancer patients with fever and granulocytopenia

1982 • 94 citations

Aspergillosis of the nose and paranasal sinuses

1982 • 88 citations

Trimethoprim/sulfamethoxazole prophylaxis in neutropenic patients

1983 • 79 citations

Prophylactic Trimethoprim-Sulfamethoxazole During Consolidation Chemotherapy for Acute Leukemia: A Controlled Trial

1981 • 79 citations

Use of oral antibiotics in protected units environment: clinical effectiveness and role in the emergence of antibiotic-resistant strains.

1974 • 67 citations

Aspergillus Pneumonia in Hematologic Malignancy

1977 • 65 citations

Modulation of human hematopoiesis by prostaglandins and lithium.

1980 • 62 citations

Allescheria (Petriellidium) boydii sinusitis in a compromised host

1977 • 60 citations

Empiric antibiotic therapy.

1978 • 60 citations

Infections in cancer patients on a protected environment-prophylactic antibiotic program

1975 • 60 citations

Amphotericin B Tolerance: A Characteristic of Candida parapsilosis Not Shared by Other Candida Species

1983 • 54 citations

Oral anticandidal prophylaxis in patients undergoing chemotherapy for acute leukemia

1977 • 53 citations

Herpes simplex infection in acute myelogenous leukemia and other hematologic malignancies: A prospective study

1981 • 53 citations

Infectious Complications Associated with Hairy Cell Leukemia

1981 • 52 citations

Alpha‐hemolytic streptococci: Clinical significance in the cancer patient

1978 • 52 citations

The Cephalosporin Antibiotics

1983 • 39 citations

Aspergillus pneumonia in hematologic malignancy. Improvements in diagnosis and therapy

1977 • 33 citations

Controversies in Oncology

1982 • 28 citations

Viral Infections and Haematological Malignancies

1976 • 27 citations

Controversies in oncology

1982 • 19 citations

Lithium enhances growth of human leukaemia cells in vitro

1982 • 16 citations

Antibiotic choice : the importance of colonisation resistance

1983 • 11 citations

In vivo stimulation of murine granulopoiesis by human urinary extract from patients with aplastic anemia.

1983 • 10 citations

Disseminated Pulmonary Blastomycosis In an Immunosuppressed Patient

2015 • 7 citations