Granulocyte Apoptosis and Its Role in the Resolution and Control of Lung Inflammation

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

1998 • 3,085 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

1989 • 1,540 citations

Phagocyte recognition of cells undergoing apoptosis

1993 • 1,000 citations

Control of vascular permeability by polymorphonuclear leukocytes in inflammation

1981 • 850 citations

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

1992 • 818 citations

Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators

1993 • 726 citations

Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes.

1996 • 613 citations

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

1992 • 605 citations

Impairment of function in aging neutrophils is associated with apoptosis.

1993 • 467 citations

Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo.

1995 • 359 citations

Regulation of Neutrophil Apoptosis by Tumor Necrosis Factor-α: Requirement for TNFR55 and TNFR75 for Induction of Apoptosis In Vitro

1997 • 296 citations

Apoptosis in human eosinophils. Programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5.

1992 • 296 citations

Glucocorticoids Promote Nonphlogistic Phagocytosis of Apoptotic Leukocytes

1999 • 292 citations

Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2

1992 • 284 citations

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

1992 • 276 citations

Eosinophil apoptosis and the resolution of airway inflammation in asthma.

1996 • 267 citations

Human monocyte-derived macrophage phagocytosis of senescent eosinophils undergoing apoptosis. Mediation by alpha v beta 3/CD36/thrombospondin recognition mechanism and lack of phlogistic response.

1996 • 244 citations

Apoptotic neutrophils are phagocytosed by fibroblasts with participation of the fibroblast vitronectin receptor and involvement of a mannose/fucose-specific lectin.

1994 • 213 citations

Neutrophil apoptosis and clearance from neonatal lungs

1991 • 204 citations

In vivo measurement of neutrophil activity in experimental lung inflammation.

1994 • 201 citations

Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro

1995 • 197 citations

Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis.

1995 • 168 citations

Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways.

1995 • 164 citations

Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis

1992 • 163 citations

Antibiotic proteins of human neutrophils.

1990 • 159 citations

Regulation of cell adhesion molecule expression and function associated with neutrophil apoptosis

1995 • 158 citations

CD44 regulates phagocytosis of apoptotic neutrophil granulocytes, but not apoptotic lymphocytes, by human macrophages.

1997 • 150 citations

Regulation of Macrophage Phagocytosis of Apoptotic Cells by cAMP

1998 • 149 citations

Transient elevations of cytosolic free calcium retard subsequent apoptosis in neutrophils in vitro.

1993 • 141 citations

Agents That Elevate cAMP Inhibit Human Neutrophil Apoptosis

1995 • 137 citations

Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils.

1988 • 128 citations

Biology of Inflammation

1956 • 85 citations

Coupling of neutrophil apoptosis to recognition by macrophages: coordinated acceleration by protein synthesis inhibitors

1997 • 64 citations

Cessation of neutrophil influx in C5a-induced acute experimental arthritis is associated with loss of chemoattractant activity from the joint space.

1989 • 28 citations

CHANGES OCCURRING IN THE MACROPHAGE SYSTEM OF THE LUNGS IN PNEUMOCOCCUS LOBAR PNEUMONIA 1

1936 • 25 citations

Inhibition of Macrophage Phagocytosis in Vitro of Aged Neutrophils Undergoing Apoptosis Increases Release of Neutrophil Contents

1993 • 9 citations

The practice of physic

1991 • 2 citations