Folate metabolism and neural tube defects: a review

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1988 • 11,687 citations

Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

1992 • 3,145 citations

Prevention of neural tube defects: Results of the Medical Research Council vitamin study

1992 • 2,294 citations

The Metabolic Basis of Inherited Diseases

1972 • 1,762 citations

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group.

1991 • 1,717 citations

Methionine metabolism in mammals

1990 • 1,463 citations

Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects.

1981 • 678 citations

Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects

1989 • 629 citations

Handbook of Vitamins

1991 • 616 citations

Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.

1991 • 615 citations

Harrison's Principles of Internal Medicine.

1980 • 600 citations

FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCES

1983 • 504 citations

Periconceptional Use of Multivitamins and the Occurrence of Neural Tube Defects

1988 • 487 citations

Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects.

1993 • 486 citations

Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.

1988 • 479 citations

Spina Bifida in Infants of Women Treated with Carbamazepine during Pregnancy

1991 • 463 citations

Multivitamin/Folic Acid Supplementation in Early Pregnancy Reduces the Prevalence of Neural Tube Defects

1989 • 462 citations

Periconceptional Folic Acid Exposure and Risk of Occurrent Neural Tube Defects

1993 • 405 citations

Maternal hyperhomocysteinemia: A risk factor for neural-tube defects?

1994 • 402 citations

Therapeutic Abortions with a Folic Acid Antagonist, 4-Aminopteroylglutamic Acid (4-Amino P. G. A.) Administered by the Oral Route

1952 • 402 citations

Dietary folate as a risk factor for neural‐tube defects: evidence from a case‐control study in Western Australia

1989 • 353 citations

FOLIC ACID METABOLISM AND HUMAN EMBRYOPATHY

1965 • 349 citations

Vitamin B₁₂-Folate Interrelationships

1985 • 306 citations

Definition of insanity.

1984 • 292 citations

ACUTE CARBON TETRACHLORIDE POISONING IN 19 PATIENTS: IMPLICATIONS FOR DIAGNOSIS AND TREATMENT

1985 • 278 citations

THE METHYL FOLATE TRAP A physiological response in man to prevent methyl group deficiency in kwashiorkor (methionine deficiency) and an explanation for folic-acid-induced exacerbation of subacute combined degeneration in pernicious anaemia

1981 • 266 citations

The Absence of a Relation between the Periconceptional Use of Vitamins and Neural-Tube Defects

1989 • 256 citations

Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity

1972 • 232 citations

Anticonvulsant Drugs and Congenital Abnormalities

1968 • 218 citations

THE ROLE OF FOLIC ACID IN PREGNANCY WITH PARTICULAR REFERENCE TO ANAEMIA, ABRUPTION AND ABORTION

1965 • 210 citations

Inherited disorders of folate transport and metabolism

1995 • 201 citations

Primary prevention of neural tube defects with folic acid supplementation: Cuban experience

1990 • 190 citations

Effect of oral folic acid supplements on zinc, copper, and iron absorption and excretion

1984 • 167 citations

Is disordered folate metabolism the basis for the genetic predisposition to neural tube defects?

1987 • 160 citations

Alteration of embryonic folate metabolism by valproic acid during organogenesis: implications for mechanism of teratogenesis.

1992 • 155 citations

Anticonvulsants, folate levels, and pregnancy outcome: A prospective study

1987 • 138 citations

ALGODYSTROPHY AFTER AORTIC BIFURCATION SURGERY

1984 • 137 citations

Teratogenicity of anticonvulsant drugs. I: Review of the literature

1984 • 126 citations

Methionine and neural tube closure in cultured rat embryos: Morphological and biochemical analyses

1990 • 107 citations

Whole Rat Embryos Require Methionine for Neural Tube Closure when Cultured on Cow Serum

1989 • 87 citations

Measurement of Serum Folate Levels and Serum Folic Acid-binding Protein by 3H-PGA Radioassay

1973 • 81 citations

Folic Acid and Vitamin B 12 Deficiency in Pregnancy and in the Neonatal Period

1984 • 74 citations

Effect of folic acid supplementation on congenital malformations due to anticonvulsive drugs

1984 • 72 citations

Effects of sub-50 oral contraceptives on homocysteine metabolism: A preliminary study

1992 • 72 citations

Folic acid and vitamin B12 deficiency in pregnancy and in the neonatal period.

1984 • 69 citations

Neural tube defects in spontaneous abortions

1986 • 69 citations

Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

1993 • 67 citations

Purification of folate binding factor in normal umbilical cord serum.

1975 • 62 citations

Eschericha coli B N5-methyltetrahydrofolate-homocysteine methyl-transferase: Sequential formation of bound methylcobalamin with S-adenosyl-l-methionine and N5-methyltetrahydrofolate

1969 • 62 citations

Clinical implications of hepatic microsomal enzyme induction by antiepileptic drugs

1987 • 59 citations

Cobalamin and folate: recent developments.

1992 • 53 citations

Folic Acid Nonresponsive Homocystinuria Due to Methylenetetrahydrofolate Reductase Deficiency

1977 • 47 citations

Maternal zinc and fetal neural tube defects

1992 • 46 citations

Dihydrofolate Reductase Deficiency Causing Megaloblastic Anemia in Two Families

1976 • 45 citations

Stereospecific in vitro embryotoxicity of l-homocysteine in pre- and post-implantation rodent embryos

1993 • 42 citations

Congenital malformations due to anticonvulsive drugs.

1975 • 40 citations

Folic acid and dilantin antagonism in pregnancy.

1974 • 30 citations

Serum homocysteine in routine evaluation of potential vitamin B₁₂ and folate deficiency

1990 • 30 citations

Update of New Risk Factors and Prevention of Neural-Tube Defects

1993 • 28 citations

The influence of dietary folate supplementation on the incidence of teratogenesis in zinc-deficient rats

1990 • 26 citations

Effect of anticonvulsant drugs on the rate of folate catabolism in mice.

1979 • 26 citations

Clinical Chemistry of Folic Acid

1986 • 24 citations

The effect of dietary zinc depletion and repletion on rats: Zn concentration in various tissues and activity of pancreatic γ-glutamyl hydrolase (EC3.4.22.12) as indices of Zn status

1990 • 18 citations

Studies in ' Pernicious Anaemia ' of Pregnancy. Part I. Preliminary Report.

1930 • 17 citations

TRANSFER OF FOLATE TO THE FETUS

1976 • 15 citations

Folate and Neural Tube Defects

1992 • 8 citations

Inborn Errors of Cobalamin (Vitamin B12) Metabolism

1990 • 1 citations

Chronic carbamazepine treatment and folate-dependent one-carbon metabolism.

1990 • 1 citations

Deleted Work

1955 • 0 citations