Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein

On the Origin of Cancer Cells

1956 • 12,141 citations

MYC oncogenes and human neoplastic disease

1999 • 1,146 citations

c-Myc transactivation of LDH-A : Implications for tumor metabolism and growth

1997 • 1,015 citations

Genomic targets of the human c-Myc protein

2003 • 956 citations

NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities

1998 • 946 citations

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

1995 • 798 citations

The ornithine decarboxylase gene is a transcriptional target of c-Myc.

1993 • 759 citations

Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter

2000 • 716 citations

The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins

1998 • 675 citations

The MYC protein activates transcription of the alpha-prothymosin gene.

1991 • 589 citations

Histone-like TAFs within the PCAF Histone Acetylase Complex

1998 • 534 citations

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27

1999 • 497 citations

The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

2000 • 479 citations

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

1989 • 475 citations

Myc pathways provoking cell suicide and cancer

2003 • 461 citations

Identification of CDK4 as a target of c-MYC

2000 • 457 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

MYC recruits the TIP60 histone acetyltransferase complex to chromatin

2003 • 379 citations

Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor

2000 • 362 citations

A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses.

1994 • 350 citations

Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

2001 • 334 citations

Cyclins D1 and D2 mediate Myc-induced proliferation via sequestration of p27Kip1 and p21Cip1

1999 • 333 citations

The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation

1999 • 316 citations

Mi-2/NuRD: multiple complexes for many purposes

2003 • 296 citations

Direct Repression of FLIP Expression by c-myc Is a Major Determinant of TRAIL Sensitivity

2004 • 242 citations

Novel Substrate Specificity of the Histone Acetyltransferase Activity of HIV-1-Tat Interactive Protein Tip60

1997 • 234 citations

Neoplastic Transformation by Truncated Alleles of Human NOTCH1/TAN1 and NOTCH2

1997 • 234 citations

Tip60 acetylates six lysines of a specific class in core histones in vitro

1998 • 203 citations

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

2005 • 199 citations

HMG-I/Y, a New c-Myc Target Gene and Potential Oncogene

2000 • 179 citations

Emerging roles of MTA family members in human cancers

2003 • 177 citations

An E-Box-Mediated Increase in cad Transcription at the G₁/S-Phase Boundary Is Suppressed by Inhibitory c-Myc Mutants

1995 • 169 citations

An Amino-Terminal c-Myc Domain Required for Neoplastic Transformation Activates Transcription

1990 • 153 citations

TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins

2002 • 137 citations

The Role of Metastasis-Associated Protein 1 in Prostate Cancer Progression

2004 • 130 citations

Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis

2000 • 123 citations

Definition of Regions in Human c-myc that are Involved in Transformation and Nuclear Localization

1987 • 106 citations

Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytes

2002 • 102 citations

Tumor induction by the c-Myc target genes rcl and lactate dehydrogenase A.

2000 • 100 citations

Genetic basis of human breast cancer metastasis.

2001 • 98 citations

Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.

1987 • 78 citations

Tumor metastasis-associated humanMTA1 gene: Its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides

2000 • 69 citations

The role of MTA1 gene expression in human hepatocellular carcinoma.

2003 • 69 citations

Direct Activation of HSP90A Transcription by c-Myc Contributes to c-Myc-induced Transformation

2004 • 67 citations

Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells

2004 • 66 citations

Dose-comparative monotherapy trials of ZD1839 in previously treated non–small cell lung cancer patients

2003 • 61 citations

Another Tie that Binds the MTA Family to Breast Cancer

2003 • 59 citations

Antisense therapy directed to protein kinase C-alpha (affinitak, LY900003/ISIS 3521): Potential role in breast cancer

2003 • 37 citations

Inactivation of Myc in Murine Two-Hit B lymphomas Causes Dormancy with Elevated Levels of Interleukin 10 Receptor and CD20: Implications for Adjuvant Therapies

2005 • 31 citations

The association of the expression of MTA1, nm23H1 with the invasion, metastasis of ovarian carcinoma.

2003 • 26 citations