α4 Integrins Regulate the Proliferation/Differentiation Balance of Multilineage Hematopoietic Progenitors In Vivo

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1996 • 2,374 citations

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1998 • 1,535 citations

Differentiation and proliferation of hematopoietic stem cells

1993 • 1,417 citations

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development

1995 • 792 citations

The Biology of Hematopoietic Stem Cells

1995 • 775 citations

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.

1991 • 628 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

A common precursor for primitive erythropoiesis and definitive haematopoiesis

1997 • 601 citations

Regulation of Hemopoiesis by Bone Marrow Stromal Cells and Their Products

1990 • 546 citations

The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen.

1995 • 529 citations

Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions

1991 • 522 citations

Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin.

1993 • 455 citations

The pathophysiologic role of alpha 4 integrins in vivo.

1994 • 380 citations

Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins

1996 • 348 citations

Differential Requirements for α4 Integrins during Fetal and Adult Hematopoiesis

1996 • 347 citations

Integrins, Oncogenes, and Anchorage Independence

1997 • 345 citations

Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

1991 • 335 citations

TECK: A Novel CC Chemokine Specifically Expressed by Thymic Dendritic Cells and Potentially Involved in T Cell Development

1997 • 292 citations

The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

1998 • 275 citations

The Integrin α9β1 Mediates Adhesion to Activated Endothelial Cells and Transendothelial Neutrophil Migration through Interaction with Vascular Cell Adhesion Molecule-1

1999 • 258 citations

Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration.

1987 • 230 citations

Anti–VLA4/VCAM-1—Induced Mobilization Requires Cooperative Signaling Through the kit/mkit Ligand Pathway

1998 • 228 citations

Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors.

1994 • 228 citations

Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alterations in their interaction with fibronectin.

1991 • 224 citations

VLA4/VCAM‐1接着経路が骨髄とひ臓の間で移植したマウス造血幹細胞の対照的な定着機構を決定する

1995 • 204 citations

Simplified typing of mouse hemoglobin (Hbb) phenotypes using cystamine

1978 • 200 citations

Circulation of Hematopoietic Progenitors in the Mouse Embryo

1996 • 193 citations

Cytokine regulation of proliferation and cell adhesion are correlated events in human CD34+ hemopoietic progenitors

1996 • 184 citations

Differential Chemotactic Behavior of Developing T Cells in Response to Thymic Chemokines

1998 • 169 citations

Very late activation antigen 4-vascular cell adhesion molecule 1 interaction is involved in the formation of erythroblastic islands.

1995 • 160 citations

Requirement for VLA-4 and VLA-5 integrins in lymphoma cells binding to and migration beneath stromal cells in culture.

1992 • 137 citations

Globin Gene Expression Is Reprogrammed in Chimeras Generated by Injecting Adult Hematopoietic Stem Cells into Mouse Blastocysts

1998 • 129 citations

Developmental switches in the immune system

1994 • 126 citations

αdβ2 Integrin Is Expressed on Human Eosinophils and Functions as an Alternative Ligand for Vascular Cell Adhesion Molecule 1 (VCAM-1)

1998 • 119 citations

Growth-Supporting Activities of Fibronectin on Hematopoietic Stem/Progenitor Cells In Vitro and In Vivo: Structural Requirement for Fibronectin Activities of CS1 and Cell-Binding Domains

1998 • 118 citations

Expression and Function of Integrins on Hematopoietic Progenitor Cells

1997 • 116 citations

Selective Transendothelial Migration of Hematopoietic Progenitor Cells: A Role in Homing of Progenitor Cells

1999 • 111 citations

Roles for integrin very late activation antigen-4 in stroma-dependent erythropoiesis

1994 • 108 citations

Loss of attachment to fibronectin with terminal human erythroid differentiation

1990 • 107 citations

Cell adhesion and migration are regulated at distinct stages of thymic T cell development: the roles of fibronectin, VLA4, and VLA5.

1996 • 93 citations

c-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB

1997 • 86 citations

Loss of attachment to fibronectin with terminal human erythroid differentiation

1990 • 85 citations

Genetic analysis of alpha 4 integrin functions in the development of mouse skeletal muscle.

1996 • 79 citations

The Effect of α4β1-Integrin Binding Sequences of Fibronectin on Growth of Cells From Human Hematopoietic Progenitors

1998 • 74 citations

Growth-Supporting Activities of Fibronectin on Hematopoietic Stem/Progenitor Cells In Vitro and In Vivo: Structural Requirement for Fibronectin Activities of CS1 and Cell-Binding Domains

1998 • 73 citations

A critical role of VLA-4 in erythropoiesis in vivo

1996 • 70 citations

The Effect of α4β1-Integrin Binding Sequences of Fibronectin on Growth of Cells From Human Hematopoietic Progenitors

1998 • 66 citations

Hematopoietic supportive functions of mouse bone marrow and fetal liver microenvironment: dissection of granulocyte, B-lymphocyte, and hematopoietic progenitor support at the stroma cell clone level

1996 • 59 citations

Inhibition of human bone marrow lymphoid progenitor colonies by antibodies to VLA integrins.

1992 • 58 citations

The leukocyte β1 integrins

1995 • 58 citations

Identification of distinct elements of the stromal microenvironment that control human hematopoietic stem/progenitor cell growth and differentiation.

1998 • 47 citations

Importance of cell-cell interactions in regulation of erythropoiesis

1997 • 47 citations

Vascular cell adhesion molecule‐1 expression by hematopoiesis‐supporting stromal cells is not essential for lymphoid or myeloid differentiation in vivo or in vitro

1996 • 44 citations

Functions of α4- and β7-Integrins in Hematopoiesis, Lymphocyte Trafficking and Organ Development

1998 • 23 citations

Specific Domains of Fibronectin Mediate Adhesion and Migration of Early Murine Erythroid Progenitors

1997 • 22 citations