Effects of aminoguanidine in preventing experimental diabetic nephropathy are related to the duration of treatment

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Role of Oxidative Stress in Development of Complications in Diabetes

1991 • 3,774 citations

Determination of hydroxyproline

1967 • 1,583 citations

Structural-functional relationships in diabetic nephropathy.

1984 • 1,202 citations

Aminoguanidine Prevents Diabetes-Induced Arterial Wall Protein Cross-Linking

1986 • 1,154 citations

Iodination of proteins, glycoproteins, and peptides using a solid-phase oxidizing agent, 1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril (Iodogen)

1981 • 1,135 citations

Advanced Glycosylation End Products in Patients with Diabetic Nephropathy

1991 • 925 citations

Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues.

1993 • 764 citations

Accumulation of Maillard reaction products in skin collagen in diabetes and aging.

1993 • 764 citations

Glycation and Diabetic Complications

1994 • 634 citations

Die enzymatische Bestimmung von Glucose und Fructose nebeneinander

1961 • 506 citations

Immunochemical detection of advanced glycosylation end products in vivo.

1992 • 496 citations

Validation in awake rats of a tail-cuff method for measuring systolic pressure.

1973 • 492 citations

Advanced glycation end products induce glomerular sclerosis and albuminuria in normal rats.

1994 • 463 citations

Glycation, Glycoxidation, and Cross-Linking of Collagen by Glucose: Kinetics, Mechanisms, and Inhibition of Late Stages of the Maillard Reaction

1994 • 453 citations

Mesangial Expansion as a Central Mechanism for Loss of Kidney Function in Diabetic Patients

1989 • 414 citations

Retardation by aminoguanidine of development of albuminuria, mesangial expansion, and tissue fluorescence in streptozocin-induced diabetic rat

1991 • 395 citations

Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure

1994 • 374 citations

Determination of membrane thickness distribution from orthogonal intercepts

1979 • 352 citations

Maillard Reaction-Mediated Molecular Damage to Extracellular Matrix and Other Tissue Proteins in Diabetes, Aging, and Uremia

1992 • 309 citations

Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease.

1994 • 298 citations

Development of glomerular lesions in experimental long-term diabetes in the rat

1982 • 261 citations

Hemoglobin-AGE: A Circulating Marker of Advanced Glycosylation

1992 • 255 citations

Human and rat mesangial cell receptors for glucose-modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy.

1991 • 243 citations

Prevention of diabetic glomerulopathy in streptozotocin diabetic rats by insulin treatment

1979 • 173 citations

Increased collagen-linked pentosidine levels and advanced glycosylation end products in early diabetic nephropathy.

1993 • 166 citations

Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin-diabetic rats

1992 • 139 citations

The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat

1995 • 132 citations

Aminoguanidine inhibits the development of accelerated diabetic retinopathy in the spontaneous hypertensive rat

1994 • 126 citations

Amelioration of Mesangial Volume and Surface Alterations Following Islet Transplantation in Diabetic Rats

1980 • 123 citations

Amadori glucose adducts modulate mesangial cell growth and collagen gene expression

1994 • 110 citations

Aminoguanidine ameliorates albuminuria in diabetic hypertensive rats

1992 • 110 citations

Prevention of Diabetes-Increased Aging Effect on Rat Collagen-Linked Fluorescence by Aminoguanidine and Rutin

1990 • 105 citations

Effects of genetic hypertension on diabetic nephropathy in the rat ??? functional and structural characteristics

1988 • 97 citations

Advanced glycosylation end-products in experimental murine diabetic nephropathy: effect of islet isografting and of aminoguanidine.

1989 • 94 citations

Immunochemical Detection of Advanced Glycation End Products in Renal Cortex From STZ-Induced Diabetic Rat

1993 • 92 citations

High Glucose Concentration Causes a Decrease in Mesangium Degradation: A Factor in the Pathogenesis of Diabetic Nephropathy

1994 • 92 citations

Prevention of glomerular basement membrane thickening by aminoguanidine in experimental diabetes mellitus

1991 • 91 citations

Early glycosilation products induce glomerular hyperfiltration in normal rats

1992 • 77 citations

Antihypertensive therapy in a model combining spontaneous hypertension with diabetes

1992 • 50 citations

Glycation of crystalline in lenses from aging and diabetic individuals

1992 • 41 citations

Aminoguanidine does not inhibit the initial phase of experimental diabetic retinopathy in rats

1995 • 40 citations

The Effects of Perindopril and Triple Therapy in a Normotensive Model of Diabetic Nephropathy

1993 • 39 citations

Effects of matrix glycation on mesangial cell adhesion, spreading and proliferation

1994 • 36 citations

Effects of dietary protein content in streptozotocin-diabetic rats

1989 • 34 citations

Aminoguanidine decreases urinary albumin and high-molecular-weight proteins in diabetic rats

1991 • 30 citations

Aminoguanidine reduces regional albumin clearance but not urinary albumin excretion in streptozotocin-diabetic rats

1994 • 30 citations

A technique to reduce fixation artifacts to kidney proximal tubules

1984 • 20 citations