Caspases and inhibitor of apoptosis proteins in cutaneous and mucosal melanoma: expression profile and clinicopathologic significance

Final Version of the American Joint Committee on Cancer Staging System for Cutaneous Melanoma

2001 • 2,658 citations

IAP proteins: blocking the road to death's door

2002 • 1,753 citations

Apoptosis and melanoma chemoresistance

2003 • 806 citations

Inhibitor of Apoptosis Proteins: Translating Basic Knowledge into Clinical Practice

2004 • 499 citations

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

2006 • 474 citations

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

2000 • 407 citations

Sinonasal Tract and Nasopharyngeal Melanomas: A Clinicopathologic Study of 115 Cases With a Proposed Staging System

2003 • 366 citations

Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis

2004 • 357 citations

Caspase activation, inhibition, and reactivation: A mechanistic view

2004 • 334 citations

Apoptosis-regulating proteins as targets for drug discovery

2001 • 327 citations

Primary mucosal melanoma

2007 • 287 citations

Apoptosis and melanoma: molecular mechanisms

2003 • 262 citations

Identification of Hypoxia-inducible Factor 1 Ancillary Sequence and Its Function in Vascular Endothelial Growth Factor Gene Induction by Hypoxia and Nitric Oxide

2001 • 260 citations

Progression in Cutaneous Malignant Melanoma Is Associated with Distinct Expression Profiles

2004 • 241 citations

Caspase activation – stepping on the gas or releasing the brakes? Lessons from humans and flies

2004 • 235 citations

Death receptors and melanoma resistance to apoptosis

2003 • 210 citations

Drug resistance in melanoma: mechanisms, apoptosis, and new potential therapeutic targets.

2001 • 206 citations

Apoptosis Regulators and Responses in Human Melanocytic and Keratinocytic Cells

2003 • 144 citations

Expression of the Novel Inhibitor of Apoptosis Survivin in Normal and Neoplastic Skin

1999 • 116 citations

Overexpression of caspase-3 in hepatocellular carcinomas

2004 • 104 citations

The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization

2007 • 100 citations

Prognostic Factors for Malignant Melanoma of the Squamous Mucosa of the Head and Neck

2002 • 99 citations

Survivin, bcl-2, bax, and bcl-X Gene Expression in Sentinel Lymph Nodes From Melanoma Patients

2003 • 98 citations

Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma

2005 • 94 citations

Survivin expression by metastatic melanoma predicts poor disease outcome in patients receiving adjuvant polyvalent vaccine

2005 • 79 citations

Survivin nuclear labeling index: a superior biomarker in superficial urothelial carcinoma of human urinary bladder

2006 • 65 citations

Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma

2007 • 51 citations

Apoptosis and melanoma: how new insights are effecting the development of new therapies for melanoma

2006 • 47 citations

Melanoma inhibitor of apoptosis protein is expressed differentially in melanoma and melanocytic naevus, but similarly in primary and metastatic melanomas

2005 • 44 citations

Elevated procaspase levels in human melanoma

2001 • 41 citations

Nuclear expression of the antiapoptotic protein survivin in malignant melanoma

2006 • 40 citations

Constructing Tissue Microarrays Without Prefabricating Recipient Blocks

2005 • 34 citations

Immunohistochemical detection of XIAP in melanoma

2007 • 32 citations

Apoptosis and Proliferation Markers in Diffusely Infiltrating Astrocytomas

2006 • 29 citations

Survivin as a useful adjunct marker for the grading of papillary urothelial carcinoma.

2008 • 20 citations

Survivin as a Useful Adjunct Marker for the Grading of Papillary Urothelial Carcinoma

2008 • 19 citations