Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease

Chronic graft-versus-host syndrome in man

1980 • 2,438 citations

Chronic graft-versus-host disease

2003 • 910 citations

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

2002 • 816 citations

Cutting Edge: A Role for B Lymphocyte Stimulator in Systemic Lupus Erythematosus

2001 • 723 citations

Excess BAFF Rescues Self-Reactive B Cells from Peripheral Deletion and Allows Them to Enter Forbidden Follicular and Marginal Zone Niches

2004 • 711 citations

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

2002 • 679 citations

Defective B cell tolerance checkpoints in systemic lupus erythematosus

2005 • 677 citations

Disturbed Peripheral B Lymphocyte Homeostasis in Systemic Lupus Erythematosus

2000 • 621 citations

Mismatches of Minor Histocompatibility Antigens between HLA-Identical Donors and Recipients and the Development of Graft-Versus-Host Disease after Bone Marrow Transplantation

1996 • 603 citations

Synthesis and release of B-lymphocyte stimulator from myeloid cells

2001 • 576 citations

Reduced Competitiveness of Autoantigen-Engaged B Cells due to Increased Dependence on BAFF

2004 • 564 citations

Identification and characterization of circulating human transitional B cells

2005 • 561 citations

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire

1994 • 541 citations

The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome

2003 • 541 citations

Rituximab for steroid-refractory chronic graft-versus-host disease

2006 • 439 citations

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells.

1993 • 413 citations

Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission

2004 • 399 citations

TNF Family Member B Cell-Activating Factor (BAFF) Receptor-Dependent and -Independent Roles for BAFF in B Cell Physiology

2004 • 365 citations

The role of APRIL and BAFF in lymphocyte activation

2005 • 344 citations

Self-Tolerance Checkpoints in B Lymphocyte Development

1995 • 329 citations

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus

2005 • 322 citations

Impaired early B cell tolerance in patients with rheumatoid arthritis

2005 • 313 citations

Cutting Edge: BLyS Enables Survival of Transitional and Mature B Cells Through Distinct Mediators

2002 • 309 citations

Bm1–Bm5 Classification of Peripheral Blood B Cells Reveals Circulating Germinal Center Founder Cells in Healthy Individuals and Disturbance in the B Cell Subpopulations in Patients with Primary Sjögren’s Syndrome

2001 • 308 citations

Sites and Stages of Autoreactive B Cell Activation and Regulation

2008 • 304 citations

Comparative outcome of nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients older than 50 years of age

2005 • 303 citations

Identification of HLA-A2–restricted CD8+ Cytotoxic T Cell Responses in Primary Biliary Cirrhosis

2002 • 280 citations

Elevated serum BAFF levels in patients with systemic sclerosis: Enhanced BAFF signaling in systemic sclerosis B lymphocytes

2005 • 260 citations

Normal B Cell Homeostasis Requires B Cell Activation Factor Production by Radiation-resistant Cells

2003 • 259 citations

Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus

2001 • 254 citations

Endothelial injury mediated by cytotoxic T lymphocytes and loss of microvessels in chronic graft versus host disease

2002 • 253 citations

Regulated Expression of BAFF-Binding Receptors during Human B Cell Differentiation

2007 • 251 citations

High Levels of B-Cell Activating Factor in Patients with Active Chronic Graft-Versus-Host Disease

2007 • 244 citations

Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease

2007 • 215 citations

Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations

2005 • 212 citations

Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody

2003 • 203 citations

Minor Histocompatibility Antigen DBY Elicits a Coordinated B and T Cell Response after Allogeneic Stem Cell Transplantation

2004 • 171 citations

Treatment of refractory chronic GVHD with rituximab: a GITMO study

2007 • 169 citations

Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers

2001 • 164 citations

Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors

2003 • 156 citations

B cell reconstitution after human bone marrow transplantation: recapitulation of ontogeny?

1993 • 145 citations

Biomarkers in newly diagnosed pediatric-extensive chronic graft-versus-host disease: a report from the Children's Oncology Group

2007 • 141 citations

Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation

2004 • 141 citations

Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation

2008 • 139 citations

Immunity of patients surviving 20 to 30 years after allogeneic or syngeneic bone marrow transplantation

2001 • 138 citations

Increased Expression of CD27 on Activated Human Memory B Cells Correlates with Their Commitment to the Plasma Cell Lineage

2005 • 136 citations

The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-vs-host disease and immune recovery

2006 • 135 citations

B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis

2005 • 126 citations

Requirement for B cells in T cell priming to minor histocompatibility antigens and development of graft-versus-host disease.

1995 • 122 citations

Deposition of IgM and Complement at the Dermoepidermal Junction in Acute and Chronic Cutaneous Graft-Vs-Host Disease in Man

1978 • 119 citations

Space, Selection, and Surveillance: Setting Boundaries with BLyS

2006 • 106 citations

Chronic elevation of plasma corticosterone causes reductions in the number of cycling cells of the B lineage in murine bone marrow and induces apoptosis.

1993 • 105 citations

Expression and occupancy of BAFF‐R on B cells in systemic lupus erythematosus

2005 • 103 citations

A New Murine Model for Bronchiolitis Obliterans Post–Bone Marrow Transplant

2007 • 101 citations

Deposition of IgM and Complement at the Dermoepidermal Junction in Acute and Chronic Cutaneous Graft-Vs-Host Disease in Man

1978 • 100 citations

BAFF and the plasticity of peripheral B cell tolerance

2008 • 78 citations

Transplantation’s Greatest Challenges: Advances in Chronic Graft-versus-Host Disease

2007 • 68 citations

VCAM-1-positive stromal cells from human bone marrow producing cytokines for B lineage progenitors and for plasma cells: SDF-1, flt3L, and BAFF

2006 • 52 citations

Autoantibodies in chronic GVHD: high prevalence of antinucleolar antibodies.

1990 • 46 citations

Cutting Edge: B Cells Promote CD8+ T Cell Activation in MRL-FaslprMice Independently of MHC Class I Antigen Presentation

2000 • 37 citations

Reconstitution of Membrane IgD− (mIgD−) B Cells After Marrow Transplantation Lags Behind the Reconstitution of mIgD+ B Cells

1997 • 33 citations

Abnormal CD4:CD8 ratios and delayed germinal center reconstitution in lymph nodes of human graft recipients with graft-versus-host disease (GVHD): an immunohistological study.

1992 • 32 citations

Inter-rater agreement in defining chemical incidents at the National Poisons Information Service, London

2004 • 3 citations