The relationship of the (Na++K+)-activated enzyme system to transport of sodium and potassium across the cell membrane

The influence of some cations on an adenosine triphosphatase from peripheral nerves

1957 • 2,211 citations

Enzymatic Basis for Active Transport of Na⁺ and K⁺ Across Cell Membrane

1965 • 2,008 citations

Simple Allosteric Model for Membrane Pumps

1966 • 1,271 citations

Current Topics in Bioenergetics

1991 • 1,190 citations

Biochemical Aspects of Active Transport

1967 • 835 citations

Further investigations on a Mg++ + Na+-activated adenosintriphosphatase, possibly related to the active, linked transport of Na+ and K+ across the nerve membrane

1960 • 799 citations

A Phosphorylated Intermediate in Adenosine Triphosphate-dependent Sodium and Potassium Transport across Kidney Membranes

1965 • 487 citations

Membranes and ion transport

1970 • 484 citations

Flexibility of an Active Center in Sodium-Plus-Potassium Adenosine Triphosphatase

1969 • 476 citations

Preparation from mammallian brain and kidney of the enzyme system involved in active transport of Na+ and K+

1962 • 441 citations

The asymmetrical stimulation of a membrane adenosine triphosphatase in relation to active cation transport

1962 • 355 citations

Binding of Adenosine Triphosphate to Sodium and Potassium Ion-stimulated Adenosine Triphosphatase

1971 • 349 citations

Studies on the interaction of ouabain and other cardio-active steroids with sodium-potassium-activated adenosine triphosphatase.

1968 • 348 citations

The effects of injecting ‘energy‐rich’ phosphate compounds on the active transport of ions in the giant axons of Loligo

1960 • 322 citations

Purification of the Sodium- and Potassium-dependent Adenosine Triphosphatase from Canine Renal Medulla

1971 • 319 citations

The ouabain‐sensitive fluxes of sodium and potassium in squid giant axons

1969 • 309 citations

Transport Across Cell Membranes

1970 • 308 citations

The behaviour of the sodium pump in red cells in the absence of external potassium

1967 • 304 citations

Sodium-Potassium-activated Adenosine Triphosphatase of Electrophorus Electric Organ

1966 • 301 citations

The stoicheiometry of the sodium pump

1967 • 300 citations

Cation Transport and Structure of the Red-Cell Plasma Membrane

1962 • 268 citations

Binding of ATP to brain microsomal ATPase Determination of the ATP-binding capacity and the dissociation constant of the enzyme-ATP complex as a function of K+ concentration

1971 • 263 citations

Membrane current and intracellular sodium changes in a snail neurone during extrusion of injected sodium

1969 • 250 citations

Purification and characterization of (Na+ + K+)-ATPase. I. The influence of detergents on the activity of (Na+ + K+)-ATPase in preparations from the outer medulla of rabbit kidney

1971 • 249 citations

MEMBRANE ADENOSINE TRIPHOSPHATASE AND CATION TRANSPORT

1968 • 246 citations

Highly specific sodium-potassium-activated adenosine triphosphatase from various tissues of rabbit

1965 • 235 citations

Studies on the Characterization of the Sodium-Potassium Transport Adenosine Triphosphatase

1971 • 231 citations

The incorporation of inorganic phosphate into adenosine triphosphate by reversal of the sodium pump

1967 • 223 citations

Purification and properties of a highly active ouabain-sensitive Na+, K+-dependent adenosinetriphosphatase from cardiac tissue

1966 • 221 citations

Kinetic Studies on a Brain Microsomal Adenosine Triphosphatase. Evidence Suggesting Conformational Changes^*

1967 • 216 citations

THE CHARACTERIZATION OF NEW ENERGY DEPENDENT CATION TRANSPORT PROCESSES IN RED BLOOD CELLS

1966 • 214 citations

The sensitivity of the sodium pump to external sodium

1967 • 206 citations

Post‐tetanic hyperpolarization and electrogenic Na pump in stretch receptor neurone of crayfish

1966 • 202 citations

Factors affecting the relative magnitudes of the sodium: potassium and sodium: sodium exchanges catalysed by the sodium pump

1967 • 196 citations

Sodium-Potassium-activated Adenosine Triphosphatase of Electrophorus Electric Organ

1968 • 182 citations

Ion transport and phosphoproteins of human red blood cells

1962 • 176 citations

Active Sodium and Potassium Transport in High Potassium and Low Potassium Sheep Red Cells

1971 • 173 citations

Evidence that a phosphorylated intermediate in a brain transport adenosine triphosphatase is an acyl phosphate.

1965 • 161 citations

Nucleotide requirements for sodium‐sodium exchange catalysed by the sodium pump in human red cells

1971 • 151 citations

Role of phospholipid in the activation of Na+, Ka+-activated adenosine triphosphatase of beef brain

1965 • 149 citations

A Second Ouabain-sensitive Sodium-dependent Adenosine Triphosphatase in Brain Microsomes

1969 • 147 citations

Oligomycin and Active Transport Reactions in Cell Membranes

1964 • 147 citations

Sodium-Potassium-activated Adenosine Triphosphatase of Electrophorus Electric Organ

1966 • 146 citations

Potassium Ions and the Binding of Cardiac Glycosides to Mammalian Cells

1970 • 146 citations

The involvement of phosphatidylserine in adenosine triphosphatase activity of the sodium pump

1970 • 144 citations

Sodium Fluxes in Internally Dialyzed Squid Axons

1968 • 142 citations

(K+)-dependent acyl phosphatase as part of the (Na+ + K+)-dependent ATPase of cell membranes

1966 • 140 citations

Potassium-ion stimulated p-nitrophenylphosphatase activity occurring in a highly specific adenosine triphosphatase preparation from rabbit brain

1966 • 129 citations

Some acyl phosphate-like properties of P32-labeled sodium-potassium-activated adenosine triphosphatase

1965 • 129 citations

Potassium activated phosphatase from human red blood cells. The mechanism of potassium activation

1969 • 125 citations

Potassium Fluxes in Dialyzed Squid Axons

1969 • 121 citations

Studies on the Na+ + K+ activated ATP hydrolysing enzyme system the role of SH groups

1963 • 116 citations

Sodium-Potassium-activated Adenosine Triphosphatase

1969 • 114 citations

Studies on plasma membranes. V. On the lipid dependence of some phosphohydrolases of isolated rat-liver plasma membranes

1968 • 110 citations

Transport Through Biological Membranes

1967 • 110 citations

Temperature-dependence of activation and inhibition of rat-brain adenosine triphosphatase activated by sodium and potassium ions

1966 • 109 citations

Factors governing movement and distribution of inorganic ions in nerve and muscle.

1968 • 106 citations

Lipoprotein Nature of Red Cell Adenosine Triphosphatase

1962 • 105 citations

Effects of Intracellular Adenosine-5'-diphosphate and Orthophosphate on the Sensitivity of Sodium Efflux from Squid Axon to External Sodium and Potassium

1970 • 102 citations

The effect of cations, g-strophanthin and oligomycin on the labeling from [32P]ATP of the (Na+ + K+)-activated enzyme system and the effect of cations and g-strophanthin on the labeling from [32P]ITP and 32Pi

1969 • 98 citations

A comparison of microsomal (Na+ + K+)-ATPase with K+-acetylphosphatase

1967 • 96 citations

The relationship between g-strophanthin-binding capacity and ATPase activity in plasma-membrane fragments from ox brain

1971 • 95 citations

Comparison of sources of a phosphorylated intermediate in transport ATPase

1968 • 94 citations

Phosphorylation of a purified (Na++K+) adenosine triphosphatase

1971 • 93 citations

Phosphatidyl serine requirement of (Na+-K+)-activated adenosine triphosphatase from rat kidney and brain

1967 • 93 citations

Lipid pattern and Na+−K+-dependent adenosine triphosphatase activity in the salt gland of duck before and after adaptation to hypertonic saline

1971 • 91 citations

Sodium-activated Adenosine Triphosphatase Activity of the Erythrocyte Membrane

1970 • 90 citations

Isolation and characterization of a phosphorylated intermediate in the (Na+ + K+) system-dependent ATPase

1966 • 89 citations

Purification and characterization of (Na+ + K+-ATPase. II. Preparation by zonal centrifugation of highly active (Na+ + K+-ATPase from the outer medulla of rabbit kidneys

1971 • 86 citations

Partial inhibition of the active transport of cations in the giant axons of Loligo

1960 • 85 citations

On the specificity of the ATP-binding site of (Na+ + K+)-activated ATPase from brain microsomes

1971 • 78 citations

K+-dependent phosphatase activity observed in the presence of both adenosine triphosphate and Na+

1969 • 78 citations

The effect of magnesium, ATP, Pi, and sodium on the inhibition of the (Na+ + K+)-activated enzyme system by g-strophanthin

1971 • 73 citations

Partial purification of a soluble (Na++K+)-dependent ATPase from rabbit kidney

1970 • 71 citations

Phospholipid requirement of Na+, K+-activated adenosine triphosphatase from rat brain

1964 • 69 citations

Incorporation of inorganic phosphate-32 into a Na+, K+-ATPase preparation: Stimulation by ouabain

1968 • 66 citations

Binding of Tritiated Digoxin to Human Red Cell Ghosts

1969 • 64 citations

Potassium-activated phosphatase from human red blood cells

1970 • 62 citations

Mutual Exclusion of ATP, ADP and g-Strophanthin Binding to NaK-ATPase

1971 • 56 citations

Rêle des Phosphatides dans l'Adénosine Triphosphatase Sensitive à l'Ouabaine Localisée dans les Membranes d'Erythrocyte

1964 • 56 citations

Molecular structure in phospholipid essential to activate (Na+-K+-Mg2+)-dependent ATPase and (K+-Mg2+)-dependent phosphatase of bovine cerebral cortex

1969 • 54 citations

On the Mechanism of Na+- and K+-Stimulated Hydrolysis of Adenosine Triphosphate. 2. Comparison of Nucleotide Specificities of Na+- and K+-Activated ATPase and Na+-Dependent Phosphorylation of Cell Membranes

1968 • 53 citations

COMPARISON OF LIPID EFFECTS ON K⁺‐Mg²⁺ ACTIVATED p‐NITROPHENYL PHOSPHATASE AND Na⁺‐K⁺‐Mg²⁺ ACTIVATED ADENOSINE TRIPHOSPHATASE OF MEMBRANE¹

1969 • 52 citations

Studies on the partial reactions catalyzed by the (Na2+ + L+-activated ATPase. I. Effects of simple anions and nucleoside triphosphates on the alkali-cation specificity of the p-nitrophenylphosphatase

1971 • 46 citations

Acetyl phosphatase in brain microsomes: A partial reaction of Na+ + K+ ATPase

1967 • 45 citations

Studies on the partial reactions catalyzed by the (Na+ + K+)-activated ATPase. II. Effects of oligomycin and other inhibitors of the ATPase on the p-nitrophenylphosphatase

1971 • 42 citations

Potassium-activated phosphatase from human red blood cells

1970 • 41 citations

Acetyl phosphate as a substitute for ATP in (Na− + K+)-dependent ATPase

1971 • 38 citations

The coupling of downhill ion movements associated with reversal of the sodium pump in human red cells

1970 • 37 citations

Affinities or Apparent Affinities of the Transport Adenosine Triphosphatase System

1969 • 36 citations

An efflux of ninhydrin-positive material associated with the operation of the Na+ pump in intact crab nerve immersed in Na+-free solutions

1964 • 35 citations

Coupling and Selectivity of Sodium and Potassium Transport in Squid Giant Axons

1968 • 35 citations

Ouabain-dependent incorporation of 32P from p-nitrophenyl phosphate into a microsomal phosphatase.

1970 • 34 citations

Comparative Studies of K^⊕-p-Nitrophenylphosphatase, K^⊕-Acylphosphatase and (Na^⊕+ K^⊕)Adenosinetriphosphatase in Synaptosomes of Rat Brain

1968 • 34 citations

Molecular weight of Na, K-ATPase approximated by the radiation inactivation method

1967 • 33 citations

Molecular weight estimation of membrane bound ATPase by in vacuo radiation inactivation

1968 • 32 citations

Cation influence on inorganic phosphate production in human erythrocytes

1962 • 29 citations

Electron microscopy of a microsomal fraction rich in (Na+ + K+)-ATPase and isolated from kidney cortex *1Structural changes accompanying freeze- and DOC-activation and identification of main components

1971 • 26 citations

On the reaction sequence of the K+-dependent acetyl phosphatase activity of the Na+ pump

1971 • 23 citations

Studies on the partial reactions catalyzed by the (Na+ + K+)-activated ATPase. III. Relation of K+-dependent p-nitrophenylphosphatase to Na+ transport in red cell ghosts

1971 • 22 citations

Activation by freezing of (Na + K)-ATPase in a microsomal fraction from ox kidney cortex

1971 • 20 citations

Modification of the contractile responses of actomyosin by cyclic adenosine 3′, 5′ phosphate

1963 • 20 citations

Kinetics of monovalent ion activation of the (Na+-K+)-dependent adenosine triphosphatase and a model for ion translocation and its inhibition by the cardiac glycosides

1970 • 17 citations

Spatial Orientation of the (Na++K+)-Dependent Enzymatic Reaction in the Cell Membrane

1971 • 4 citations