Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Connexin43: a protein from rat heart homologous to a gap junction protein from liver.

1987 • 1,111 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Transforming growth factor α

1988 • 707 citations

Transcriptional control in the production of liver-specific mRNAs

1981 • 593 citations

Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism.

1989 • 528 citations

Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA.

1989 • 427 citations

Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis.

1993 • 237 citations

Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens.

1993 • 237 citations

Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA.

1990 • 236 citations

The evolution of alpha-fetoprotein and albumin. II. The structures of the alpha-fetoprotein and albumin genes in the mouse.

1981 • 206 citations

CELL TYPES IN LONG‐TERM PROPAGABLE CULTURES OF RAT LIVER*

1980 • 180 citations

Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells.

1985 • 171 citations

Isolation, Culture, and Transplantation of Intrahepatic Biliary Epithelial Cells and Oval Cells

1990 • 141 citations

Development of liver tumors in transforming growth factor alpha transgenic mice.

1992 • 139 citations

Transforming Growth Factor Alpha Dramatically Enhances Oncogene-Induced Carcinogenesis in Transgenic Mouse Pancreas and Liver

1993 • 131 citations

Transforming growth factor‐α

1990 • 126 citations

Growth factors in liver development, regeneration and carcinogenesis

1991 • 113 citations

Production of hepatocellular carcinoma by oval cells: cell cycle expression of c-myc and p53 at different stages of oval cell transformation.

1989 • 102 citations

Immortalized differentiated hepatocyte lines derived from transgenic mice harboring SV40 T-antigen genes*1

1988 • 100 citations

Isozyme profiles of oval cells, parenchymal cells, and biliary cells isolated by centrifugal elutriation from normal and preneoplastic livers.

1984 • 94 citations

The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43

1992 • 92 citations

Transformation of rat hepatocytes by transfection with simian virus 40 DNA to yield proliferating differentiated cells.

1986 • 89 citations

Molecular and genetic analysis of liver oncogenesis in transforming growth factor alpha transgenic mice.

1992 • 84 citations

Effects of extracellular matrix components on the growth and differentiation of cultured rat hepatocytes

1987 • 81 citations

Transforming growth factor-alpha: an oncodevelopmental growth factor.

1990 • 66 citations

Clonal cosegregation of tumorigenicity with overexpression of c-myc and transforming growth factor alpha genes in chemically transformed rat liver epithelial cells.

1991 • 65 citations

Multiple alpha-fetoprotein RNAs in adult rat liver: cell type-specific expression and differential regulation.

1991 • 65 citations

Association between expression of transforming growth factor-alpha and progression of hepatocellular foci to neoplasms

1992 • 53 citations

Structure and Localization of Genes Encoding Aberrant and Normal Epidermal Growth Factor Receptor RNAs from A431 Human Carcinoma Cells

1985 • 41 citations

Demonstration of glucose-6-phosphatase and peroxisomal catalase activity by ultrastructural cytochemistry in oval cells from livers of carcinogen-treated rats.

1988 • 24 citations

ACTIVE PROLIFERATION OF MOUSE HEPATOCYTES IN PRIMARY CULTURE UNDER DEFINED CONDITIONS AS COMPARED TO RAT HEPATOCYTES

1988 • 18 citations

Immuno-overlay: A method for identification of hepatoma cell colonies that secrete albumin

1980 • 8 citations