Mutations in the neurofibromatosis 1 gene in sporadic malignant melanoma cell lines

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Molecular cloning: A laboratory manual

1990 • 85,659 citations

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1989 • 12,929 citations

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1990 • 11,800 citations

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1986 • 2,968 citations

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1990 • 1,882 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients

1990 • 1,471 citations

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1990 • 1,107 citations

The neurofibromatosis type 1 gene encodes a protein related to GAP

1990 • 1,099 citations

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus

1990 • 1,085 citations

The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

1990 • 984 citations

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1990 • 834 citations

Neurofibromatosis, Phenotype, Natural History, and Pathogenesis

1992 • 789 citations

Molecular cloning, primary structure, and expression of the human growth factor-activatable antiporter

1989 • 774 citations

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

1992 • 648 citations

A Clinical, Pathological, and Genetic Study of Multiple Neurofibromatosis

1956 • 499 citations

A de novo Alu insertion results in neurofibromatosis type 1

1991 • 448 citations

Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells.

1976 • 442 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

Somatic mutations in the neurofibromatosis 1 gene in human tumors

1992 • 399 citations

cDNA cloning of the type 1 neurofibromatosis gene: Complete sequence of the NF1 gene product

1991 • 391 citations

Transforming ras genes from human melanoma: a manifestation of tumour heterogeneity?

1984 • 322 citations

Homozygous deletions within human chromosome band 9p21 in melanoma.

1992 • 319 citations

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

1992 • 309 citations

Identification of the neurofibromatosis type 1 gene product.

1991 • 272 citations

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1987 • 236 citations

Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma.

1991 • 233 citations

Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression.

1989 • 220 citations

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1989 • 212 citations

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1992 • 207 citations

Identification and characterization of the neurofibromatosis type 1 protein product.

1991 • 204 citations

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1975 • 134 citations

Loss of polymorphic restriction fragments in malignant melanoma: implications for tumor heterogeneity.

1985 • 106 citations

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1983 • 85 citations

Loss of heterozygosity at autosomal and X-linked loci during tumor progression in a patient with melanoma.

1987 • 82 citations

Neurofibromatosis--the quintessential neurocristopathy: pathogenetic concepts and relationships.

1981 • 76 citations

Melanin Macroglobules As a Cellular Marker of Neurofibromatosis: A Quantitative Study

1985 • 44 citations

Direct construction of a chromosome-specificNotI linking library from flow-sorted chromosomes

1989 • 41 citations

Tightly linked markers for the neurofibromatosis type 1 gene

1987 • 39 citations

A 90 kb DNA deletion associated with neurofibromatosis type 1.

1990 • 30 citations