The 9E3/CEF4 gene and its product the chicken chemotactic and angiogenic factor (cCAF): Potential roles in wound healing and tumor development

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1991 • 1,864 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

The Molecular and Cellular Biology of Wound Repair

1988 • 1,508 citations

Cells in Stress: Transcriptional Activation of Heat Shock Genes

1993 • 1,429 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

1987 • 983 citations

Lymphotactin: a Cytokine that Represents a New Class of Chemokine

1994 • 668 citations

Chemokines, leukocyte trafficking, and inflammation

1994 • 636 citations

Induction of tenascin in healing wounds.

1988 • 563 citations

Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes

1987 • 513 citations

The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1989 • 494 citations

Three-dimensional structure of interleukin 8 in solution

1990 • 441 citations

Structure-activity relationships of chemokines

1995 • 367 citations

Crystal structure of interleukin 8: symbiosis of NMR and crystallography.

1991 • 354 citations

Amino acid sequence of human platelet factor 4.

1977 • 318 citations

Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells.

1987 • 283 citations

The Platelet-derived Growth Factor-inducible KC Gene Encodes a Secretory Protein Related to Platelet α-Granule Proteins

1989 • 257 citations

Complete covalent structure of human .beta.-thromboglobulin

1978 • 215 citations

Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein

1987 • 206 citations

Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor.

1983 • 181 citations

Isolation, crystallization, and primary amino acid sequence of human platelet factor 4.

1977 • 165 citations

E1a transactivation of the human HSP70 promoter is mediated through the basal transcriptional complex.

1989 • 147 citations

Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.

1987 • 129 citations

Primary structure of human platelet factor 4

1977 • 106 citations

Determination of the Secondary Structure of Interleukin-8 by Nuclear Magnetic Resonance Spectroscopy

1989 • 88 citations

Two burgeoning families of platelet factor 4-related proteins: mediators of the inflammatory response.

1990 • 87 citations

Functional diversity of gro gene expression in human fibroblasts and mammary epithelial cells.

1988 • 86 citations

Processing of 9E3 mRNA and regulation of its stability in normal and Rous sarcoma virus-transformed cells.

1989 • 86 citations

Extraction of a melanoma growth-stimulatory activity from culture medium conditioned by the Hs0294 human melanoma cell line.

1983 • 73 citations

Factor substitution in a human HSP70 gene promoter: TATA-dependent and TATA-independent interactions.

1990 • 69 citations

CHEMOATTRACTANT LIGANDS AND THEIR RECEPTORS

1997 • 65 citations

Urokinase‐Type Plasminogen Activator (uPA) and Its Receptor (CD87): A New Target in Tumor Invasion and Metastasis

1995 • 62 citations

THE 9E3/CEF4 GENE PRODUCT IS A CHEMOTACTIC AND ANGIOGENIC FACTOR THAT CAN INITIATE THE WOUND-HEALING CASCADE IN VIVO

1998 • 61 citations

Transformation-associated cytokine 9E3/CEF4 is chemotactic for chicken peripheral blood mononuclear cells

1993 • 57 citations

Small cytokine superfamily

1991 • 55 citations

Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.

1989 • 55 citations

v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts.

1991 • 53 citations

Rous sarcoma virus enhancer factor I is a ubiquitous CCAAT transcription factor highly related to CBF and NF-Y.

1990 • 48 citations

Plasminogen activator gene expression is induced by the src oncogene product and tumor promoters.

1990 • 47 citations

Localization of 9E3/CEF-4 in avian tissues: expression is absent in Rous sarcoma virus-induced tumors but is stimulated by injury.

1990 • 44 citations

Regulation of IL-8 production and the characteristics of the receptors for IL-8.

1992 • 44 citations

Serum and v-src increase the level of a CCAAT-binding factor required for transcription from a retroviral long terminal repeat.

1990 • 43 citations

Overview of Chemokines

1993 • 38 citations

Transcriptional activation of the CEF-4/9E3 cytokine gene by pp60v-src.

1992 • 36 citations

The v-src inducible gene 9E3/pCEF4 is regulated by both its promoter upstream sequence and its 3' untranslated region.

1991 • 32 citations

GRO: A Novel Chemotactic Cytokine

1991 • 23 citations

The 9E3 protein: immunolocalization in vivo and evidence for multiple forms in culture

1992 • 22 citations

Wound-factor-induced and cell cycle phase-dependent expression of 9E3/CEF4, the avian gro gene.

1991 • 18 citations

In vitro growth promotion in human malignant melanoma cells by fibroblast growth factor.

1982 • 17 citations

THE 9E3/CEF4 CYTOKINE: KINETICS OF SECRETION, PROCESSING BY PLASMIN, AND INTERACTION WITH EXTRACELLULAR MATRIX

1996 • 14 citations

Expression of 9E3 mRNA Is Associated with Mitogenicity, Phosphorylation, and Morphological Alteration in Chicken Embryo Fibroblasts

1990 • 12 citations

Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells.

1991 • 10 citations

src-specific immune regression of Rous sarcoma virus-induced tumors.

1993 • 9 citations

Primary Structure of Human Platelet Factor 4.

1977 • 7 citations

Expression of 9E3 mRNA is associated with mitogenicity, phosphorylation, and morphological alteration in chicken embryo fibroblasts.

1990 • 7 citations

Tumor-associated urokinase-type plasminogen activator: significance in breast cancer.

1996 • 3 citations