Calcium-induced conformational changes in the troponin-tropomyosin complexes of skeletal and cardiac muscle and their roles in the regulation of contraction-relaxation

Calcium and muscle contraction

1968 • 1,745 citations

Carp Muscle Calcium-binding Protein

1973 • 1,359 citations

Control of muscle contraction

1969 • 785 citations

The structure of F-actin and of actin filaments isolated from muscle

1963 • 560 citations

Structural Changes in the Actin- and Myosin-eontaining Filaments during Contraction

1973 • 544 citations

Structural role of tropomyosin in muscle regulation: Analysis of the X-ray diffraction patterns from relaxed and contracting muscles

1973 • 491 citations

Relaxing factor and the relaxation of muscle

1964 • 477 citations

A phosphorylated light-chain component of myosin from skeletal muscle

1973 • 301 citations

Troponin, tripomyosin, and actin interactions in the Ca²⁺ion regulation of muscle contraction

1974 • 299 citations

The amino acid sequence of rabbit skeletal muscle troponin C: Gene replication and homology with calcium ‐binding proteins from carp and hake muscle

1973 • 266 citations

The relationship between biological activity and primary structure of troponin I from white skeletal muscle of the rabbit

1976 • 246 citations

The content of troponin, tropomyosin, actin, and myosin in rabbit skeletal muscle myofibrils

1974 • 219 citations

The interaction of the calcium-binding protein (troponin C) with bivalent cations and the inhibitory protein (troponin I)

1974 • 218 citations

Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T

1978 • 209 citations

Hydrodynamic and optical properties of troponin A. Demonstration of a conformational change upon binding calcium ion

1972 • 141 citations

Ca-Regulation of Mammalian Smooth Muscle Actomyosin via a Kinase-Phosphatase-Dependent Phosphorylation and Dephosphorylation of the 20000-Mr Light Chain of Myosin

1977 • 131 citations

Dansylaziridine-labeled troponin C. A fluorescent probe of Ca2+ binding to the Ca2+-specific regulatory sites.

1978 • 123 citations

Regulatory mechanism of muscle contraction with special reference to the Ca-troponin-tropomyosin system.

1974 • 103 citations

Hydrogen Ion Titration Curves of β-Lactoglobulin¹

1959 • 87 citations

Characterization of a region of the primary sequence of troponin C involved in calcium ion-dependent interaction with troponin I

1978 • 82 citations

Phosphorylation of a light chain component of myosin from smooth muscle

1976 • 76 citations

Troponin T fragments: Physical properties and binding to troponin C

1978 • 75 citations

The effect of Mg++ on the conformation of the Ca++-binding component of troponin

1972 • 71 citations

Calcium-binding properties of cardiac and skeletal troponin C as determined by circular dichroism and ultraviolet difference spectroscopy

1978 • 70 citations

Interaction of troponin subunits. The interaction between the inhibitory and tropomyosin-binding subunits.

1979 • 66 citations

Crosslinking of troponin with dimethylimido esters

1975 • 46 citations

Physicochemical studies on the complexes troponin C with troponin T, and reconstituted troponin, and their interaction with calcium ions

1974 • 45 citations

Fluorescence and conformational changes caused by proton binding to troponin C

1974 • 45 citations

Physicochemical and biological studies on the metal-induced conformational change in troponin A. Implication of carboxyl groups in the binding of calcium ion

1973 • 45 citations

Physicochemical studies on the interaction of the calcium-binding protein (troponin C) with the inhibitory protein (troponin I) and calcium ions

1974 • 29 citations

The isolation and characterization of the tropomyosin binding component (TN-T) of bovine cardiac troponin

1976 • 23 citations

The interaction between beef cardiac troponin T and troponin I as demonstrated by ultraviolet absorption difference spectroscopy, circular dichroism, and gel filtration

1979 • 23 citations

Hydrodynamic properties of bovine cardiac troponin

1979 • 19 citations

Circular dichroism and fluorescence studies on troponin—tropomyosin interactions

1975 • 19 citations

A determination of the relative compactness of the Ca²⁺‐binding sites of a Ca²⁺‐binding fragment of troponin‐c and parvalbumin using lanthanide‐induced ¹H NMR shifts

1979 • 19 citations

The Isolation and Characterization of the ATPase Inhibitory Protein (TN-I) from Bovine Cardiac Muscle

1975 • 18 citations

A circular dichroism and biological activity study on the hybrid species formed from bovine cardiac and rabbit skeletal troponin subunits

1977 • 16 citations

Interaction of Tropomyosin with Troponin Components

1976 • 15 citations

A circular dichroism study of the interactions among the components of the bovine cardiac muscle regulatory system

1976 • 9 citations