Design and trials of AIDS vaccines

Genome organization and transactivation of the human immunodeficiency virus type 2

1987 • 842 citations

Biologic Features of HIV-1 That Correlate with Virulence in the Host

1988 • 679 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates

1989 • 662 citations

Induction of AIDS-Like Disease in Macaque Monkeys with T-Cell Tropic Retrovirus STLV-III

1985 • 629 citations

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

1988 • 621 citations

Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

1990 • 593 citations

Origins and Evolutionary Relationships of Retroviruses

1989 • 581 citations

Genetic Variation in HTLV-III/LAV Over Time in Patients with AIDS or at Risk for AIDS

1986 • 570 citations

Pathogenesis of lentivirus infections

1986 • 558 citations

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

1990 • 558 citations

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1987 • 523 citations

Antibody-Enhanced Infection by HIV-1 Via Fc Receptor-Mediated Entry

1988 • 462 citations

Distinct replicative and cytopathic characteristics of human immunodeficiency virus isolates

1988 • 443 citations

Intracellular immunization

1988 • 420 citations

A Formalin-Inactivated Whole SIV Vaccine Confers Protection in Macaques

1989 • 419 citations

Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: A molecular model for latency

1990 • 371 citations

ANTIBODY-DEPENDENT ENHANCEMENT OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INFECTION

1988 • 362 citations

Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein

1987 • 335 citations

The Fc and not CD4 Receptor Mediates Antibody Enhancement of HIV Infection in Human Cells

1989 • 328 citations

Transmission of HTLV-III Infection from Human Plasma to Chimpanzees: An Animal Model for AIDS

1984 • 325 citations

Immunopathogenic mechanisms of HIV infection: cytokine induction of HIV expression

1990 • 290 citations

Activation of caprine arthritis-encephalitis virus expression during maturation of monocytes to macrophages

1983 • 240 citations

Expression of the HTLV-III envelope gene by a recombinant vaccinia virus

1986 • 240 citations

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees

1990 • 230 citations

An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies

1989 • 222 citations

Significance of premature stop codons in env of simian immunodeficiency virus

1989 • 220 citations

Identification and Biologic Characterization of an Acutely Lethal Variant of Simian Immunodeficiency Virus from Sooty Mangabeys (SIV/SMM)

1989 • 211 citations

Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndrome

1986 • 201 citations

Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees

1987 • 197 citations

A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS

1988 • 183 citations

Rapid emergence of novel antigenic and genetic variants of equine infectious anemia virus during persistent infection

1986 • 176 citations

The expression of hybrid HIV:Ty virus-like particles in yeast

1987 • 163 citations

Determination of the rate of base-pair substitution and insertion mutations in retrovirus replication

1988 • 157 citations

Prospects for the control of AIDS by immunizing seropositive individuals

1987 • 157 citations

Induction of protective immune response in cats by vaccination with feline leukemia virus iscom.

1985 • 144 citations

Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV

1990 • 136 citations

Inactivated simian immunodeficiency virus vaccine failed to protect rhesus macaques from intravenous or genital mucosal infection but delayed disease in intravenously exposed animals

1990 • 131 citations

The cytoplasmic domain of simian immunodeficiency virus transmembrane protein modulates infectivity

1989 • 122 citations

INTERACTIONS BETWEEN HOST AND VIRAL GENOMES IN MOUSE LEUKEMIA

1977 • 109 citations

Development and Testing of AIDS Vaccines

1988 • 106 citations

Challenge of chimpanzees (Pan troglodytes) immunized with human immunodeficiency virus envelope glycoprotein gp120

1989 • 103 citations

AIDS virus env Protein Expressed from a Recombinant Vaccinia Virus

1986 • 97 citations

Neutralizing antibodies to visna lentivirus: mechanism of action and possible role in virus persistence

1986 • 93 citations

Antigenic Drift in Visna: Virus Variation During Long-term Infection of Icelandic Sheep

1983 • 92 citations

Prevention of simian acquired immune deficiency syndrome with a formalin-inactivated type D retrovirus vaccine

1986 • 91 citations

In vitro and in vivo synthesis of the hepatitis B virus surface antigen and of the receptor for polymerized human serum albumin from recombinant human adenoviruses.

1985 • 86 citations

Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies

1988 • 85 citations

V International Conference on AIDS.

1989 • 72 citations

Anti-Idiotypic Antibodies: Implications of Internal Image-Based Vaccines for Infectious Diseases

1985 • 70 citations

NEUTRALISATION OF HIV ISOLATES BY ANTI-IDIOTYPIC ANTIBODIES WHICH MIMIC THE T4 (CD4) EPITOPE: A POTENTIAL AIDS VACCINE

1987 • 69 citations

Protection against feline leukemia by vaccination with a subunit vaccine

1981 • 65 citations

Medical Science, Infectious Disease, and the Unity of Humankind

1988 • 51 citations

Synthetic peptides as vaccines

1987 • 25 citations

Report of a WHO workshop on the measurement and significance of neutralizing antibody to HIV and SIV, London, 3–5 October 1988

1990 • 7 citations

Technology growth in French research budget

1989 • 1 citations