Phase 3 Trials of Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for 1 to 4 Brain Metastases: Individual Patient Data Meta-Analysis

A Randomized Trial of Surgery in the Treatment of Single Metastases to the Brain

1990 • 3,068 citations

Recursive partitioning analysis (RPA) of prognostic factors in three radiation therapy oncology group (RTOG) brain metastases trials

1997 • 2,491 citations

Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial

2004 • 2,348 citations

Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial

2009 • 2,313 citations

Stereotactic Radiosurgery Plus Whole-Brain Radiation Therapy vs Stereotactic Radiosurgery Alone for Treatment of Brain Metastases

2006 • 2,100 citations

Postoperative Radiotherapy in the Treatment of Single Metastases to the Brain

1998 • 1,864 citations

Adjuvant Whole-Brain Radiotherapy Versus Observation After Radiosurgery or Surgical Resection of One to Three Cerebral Metastases: Results of the EORTC 22952-26001 Study

2010 • 1,827 citations

Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study

2014 • 1,277 citations

Treatment of single brain metastasis: Radiotherapy alone or combined with neurosurgery

1993 • 1,034 citations

Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases

1999 • 1,002 citations

A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis

1996 • 680 citations

A European Organisation for Research and Treatment of Cancer Phase III Trial of Adjuvant Whole-Brain Radiotherapy Versus Observation in Patients With One to Three Brain Metastases From Solid Tumors After Surgical Resection or Radiosurgery: Quality-of-Life Results

2012 • 602 citations

Radiotherapeutic and surgical management for newly diagnosed brain metastasis(es): An American Society for Radiation Oncology evidence-based guideline

2012 • 570 citations

To IPD or not to IPD?

2002 • 511 citations

Phase III Trial of Prophylactic Cranial Irradiation Compared With Observation in Patients With Locally Advanced Non–Small-Cell Lung Cancer: Neurocognitive and Quality-of-Life Analysis

2010 • 359 citations

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases

2012 • 358 citations

Microsurgery plus whole brain irradiation versus Gamma Knife surgery alone for treatment of single metastases to the brain: a randomized controlled multicentre phase III trial

2007 • 331 citations

Ipilimumab and radiation therapy for melanoma brain metastases

2013 • 273 citations

A Phase 3 Trial of Whole Brain Radiation Therapy and Stereotactic Radiosurgery Alone Versus WBRT and SRS With Temozolomide or Erlotinib for Non-Small Cell Lung Cancer and 1 to 3 Brain Metastases: Radiation Therapy Oncology Group 0320

2013 • 261 citations

A meta‐analysis evaluating stereotactic radiosurgery, whole‐brain radiotherapy, or both for patients presenting with a limited number of brain metastases

2011 • 233 citations

Statistical Analysis of Individual Participant Data Meta-Analyses: A Comparison of Methods and Recommendations for Practice

2012 • 208 citations

Erlotinib Versus Radiation Therapy for Brain Metastases in Patients With EGFR-Mutant Lung Adenocarcinoma

2014 • 95 citations

Whole brain irradiation following surgery or radiosurgery for solitary brain metastases: Mature results of a prematurely closed randomized Trans-Tasman Radiation Oncology Group trial (TROG 98.05)

2006 • 71 citations

Individual patient data meta‐analysis of time‐to‐event outcomes: one‐stage versus two‐stage approaches for estimating the hazard ratio under a random effects model

2011 • 51 citations

Individual Patient-level and Study-level Meta-analysis for Investigating Modifiers of Treatment Effect

2004 • 39 citations

Quality of Life (QOL) Analysis of the Randomized Radiation (RT) Dose-Escalation NSCLC Trial (RTOG 0617): The Rest of the Story

2013 • 30 citations