The nature of receptors regulating the formation of cyclic AMP in brain tissue

The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

1970 • 860 citations

Cyclic Nucleotide-dependent Protein Kinases

1969 • 551 citations

Dopamine Receptors in the Brain

1975 • 528 citations

The influence of chemical agents on the accumulation of adenosine 3',5'-Phosphate in slices of rabbit cerebellum.

1968 • 435 citations

Adenyl Cyclase

1962 • 415 citations

The action of norepinephrine in the rat hippocampus. I. Iontophoretic studies

1974 • 380 citations

DOPAMINE IN THE MESOLIMBIC SYSTEM OF THE RAT BRAIN: ENDOGENOUS LEVELS AND THE EFFECTS OF DRUGS ON THE UPTAKE MECHANISM AND STIMULATION OF ADENYLATE CYCLASE ACTIVITY

1974 • 342 citations

Subcellular Distribution of Adenyl Cyclase and Cyclic Phosphodiesterase in Rat Brain Cortex

1967 • 337 citations

ELEVATION OF CYCLIC GMP LEVELS IN CENTRAL NERVOUS SYSTEM BY EXCITATORY AND INHIBITORY AMINO ACIDS

1974 • 247 citations

Studies on adenosine 3',5'-phosphate in rabbit cerebral cortex.

1968 • 224 citations

Adenine derivatives as neurohumoral agents in the brain. The quantities liberated on excitation of superfused cerebral tissues

1972 • 211 citations

Relationship between adenosine concentration and oxygen supply in rat brain

1975 • 202 citations

Characterization of the adrenergic receptors mediating a rise in cyclic 3'-5'-adenosine monophosphate in rat cerebral cortex.

1973 • 184 citations

H1 and H2 receptors in the histamine-induced accumulation of cyclic AMP in guinea pig brain slices

1975 • 182 citations

Histaminergic Pathway in Rat Brain Evidenced by Lesions of the Medial Forebrain Bundle

1974 • 171 citations

Multiple cyclic nucleotide phosphodiesterase activities from rat tissues and occurrence of a calcium-plus-magnesium-ion-dependent phosphodiesterase and its protein activator

1975 • 170 citations

Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons

1974 • 162 citations

Regional and subcellular distribution of adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase in brain and pineal gland

1968 • 161 citations

Adenosine-elicited accumulation of cyclic AMP in brain slices: Potentiation by agents which inhibit uptake of adenosine

1974 • 153 citations

A potent depressant action of adenine derivatives on cerebral cortical neurones

1975 • 152 citations

ACCUMULATION OF CYCLIC ADENOSINE 3′, 5′‐MONOPHOSPHATE IN CEREBRAL CORTICAL SLICES FROM RAT AND MOUSE: STIMULATORY EFFECT OF α‐ AND β‐ADRENERGIC AGENTS AND ADENOSINE

1973 • 144 citations

α- and β-Adrenergic Receptors as Mediators of Accumulation of Cyclic Adenosine 3',5'-Monophosphate in Specific Areas of Guinea Pig Brain

1971 • 143 citations

Cyclic Adenosine 3′,5′-Monophosphate in Guinea Pig Cerebral Cortical Slices

1973 • 143 citations

Adenosine 3′,5′-Monophosphate Content in Rat Caudate Nucleus: Demonstration of Dopaminergic and Adrenergic Receptors

1974 • 137 citations

Regulation of cyclic adenosine 3',5'-monophosphate levels in guinea-pig cerebral cortex by interaction of alpha adrenergic and adenosine receptor activity.

1975 • 126 citations

INCREASE IN THE CONTENT OF ADENOSINE 3′5′‐ MONOPHOSPHATE IN MOUSE FOREBRAIN DURING SEIZURES AND PREVENTION OF THE INCREASE BY METHYLXANTHINES

1971 • 126 citations

Effect of nerve degeneration by 6-hydroxydopamine on catecholamine-stimulated adenosine 3',5'-monophosphate formation in rat cerebral cortex.

1973 • 124 citations

Effect of Norepinephrine, Histamine and Other Drugs on Cyclic 3’, 5’-AMP Formation in Brain Slices of Various Animal Species

1971 • 113 citations

Effects of neurohumoral and adrenergic agents on cyclic amp levels in various areas of the rat brain in vitro

1973 • 112 citations

Formation of cyclic adenosine 3′,5′-monophosphate from adenosine in brain slices

1970 • 97 citations

Comparison of the effects of biogenic amines on cyclic GMP and cyclic AMP levels in mouse cerebellumin vitro

1975 • 95 citations

ADENOSINE 3′,5′‐MONOPHOSPHATE IN GUINEA PIG CEREBRAL CORTICAL SLICES: EFFECTS OF α‐ AND β‐ADRENERGIC AGENTS, HISTAMINE, SEROTONIN AND ADENOSINE

1973 • 85 citations

Stimulated Formation of Cyclic Adenosine 3′:5′-Monophosphate by Aspartate and Glutamate in Cerebral Cortical Slices of Guinea Pig

1974 • 80 citations

PREPARATION AND PROPERTIES OF A CELL‐FREE, HORMONALLY RESPONSIVE ADENYLATE CYCLASE FROM GUINEA PIG BRAIN¹

1974 • 75 citations

Cyclic Adenosine 3′,5′-Monophosphate in Guinea Pig Cerebral Cortical Slices

1973 • 72 citations

Accumulation of adenosine cyclic 3',5'-monophosphate in rat cerebral cortical slices. Stimulatory effect of alpha and beta adrenergic agents after treatment with 6-hydroxydopamine, 2,3,5-trihydroxyphenethylamine, and dihydroxytryptamines.

1973 • 69 citations

Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 1. Structure-activity relation of agonists and antagonists of biogenic amines and of tricyclic tranquilizers and antidepressants

1972 • 65 citations

Cyclic Adenosine 3′,5′-Monophosphate in Guinea Pig Cerebral Cortical Slices

1973 • 64 citations

CHARACTERISTICS OF THE CATECHOLAMINE AND HISTAMINE RECEPTOR SITES MEDIATING ACCUMULATION OF CYCLIC ADENOSINE 3′,5′‐MONOPHOSPHATE IN GUINEA PIG BRAIN¹

1973 • 64 citations

Norepinephrine-Sensitive Adenylate Cyclases in Rat Brain: Relation to Behavior and Tyrosine Hydroxylase

1974 • 61 citations

Regulation of adenosine cyclic 3',5'-phosphate formation in cerebral cortical slices. Interaction among norepinephrine, histamine, serotonin.

1971 • 61 citations

Histamine‐elicited accumulations of cyclic adenosine 3′,5′‐monophosphate in guinea‐pig brain slices: Effect of H₁‐ and H₂‐antagonists

1975 • 60 citations

Norepinephrine-Sensitive Systems Generating Adenosine 3',5'-Monophosphate: Increased Responses in Cerebral Cortical Slices from Reserpine-Treated Rats

1974 • 56 citations

Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.

1973 • 55 citations

Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase

1973 • 53 citations

Stimulation of adenosine 3',5'-monophosphate formation in rat cerebral cortical slices by methoxamine: interaction with an alpha adrenergic receptor.

1975 • 48 citations

Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine.

1975 • 48 citations

Histamine H2 receptors and cyclic AMP in brain

1974 • 47 citations

Evaluation of electrical pulses and elevated levels of potassium ions as stimulants of adenosine 3', 5'-monophosphate (cyclic AMP) accumulation in guinea-pig brain.

1973 • 45 citations

Accumulation of adenosine 3′, 5′-monophosphate in rat brain slices: Effects of prostaglandins

1975 • 44 citations

The response of human cerebrum adenyl cyclase to biogenic amines

1971 • 43 citations

Correlation between brain adenyl cyclase activity and spontaneous motor activity in rats after chronic reserpine treatment

1974 • 40 citations

Characteristics of the amino acid receptor site mediating formation of cyclic adenosine 3',5'-monophosphate in mammalian brains.

1975 • 34 citations

Cyclic Adenosine Monophosphate in Cerebral Cortex

1975 • 32 citations

The effects of prostaglandins on cyclic-AMP formation in cerebral cortex of different mammalian species

1972 • 26 citations

Accumulation of adenosine 3′,5′‐monophosphate in incubated slices from discrete regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin and adenosine

1973 • 23 citations

Inhibition of glutamate-elicited accumulation of adenosine cyclic 3',5'-monophosphate in brain slices by alpha, omega-diaminocarboxylic acids.

1975 • 23 citations

FUNCTIONAL COMPARTMENTS OF ADENINE NUCLEOTIDES SERVING AS PRECURSORS OF ADENOSINE 3′,5′‐MONOPHOSPHATE IN MOUSE CEREBRAL CORTEX

1975 • 21 citations

Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig and rat

1974 • 13 citations