N‐Acetylaspartylglutamate Inhibits Forskolin‐Stimulated Cyclic AMP Levels via a Metabotropic Glutamate Receptor in Cultured Cerebellar Granule Cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

1992 • 539 citations

Selective release of glutamate from cerebellar granule cells differentiating in culture

1982 • 501 citations

Coupling of Inositol Phospholipid Metabolism with Excitatory Amino Acid Recognition Sites in Rat Hippocampus

1986 • 444 citations

The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells

1986 • 431 citations

Receptors linked to inhibition of adenylate cyclase: additional signaling mechanisms

1988 • 339 citations

Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. Identification and characterization of a novel N-acetylated alpha-linked acidic dipeptidase activity from rat brain.

1987 • 303 citations

Comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn

1988 • 210 citations

Activation of Cyclic AMP‐Generating Systems in Brain Membranes and Slices by the Diterpene Forskolin: Augmentation of Receptor‐Mediated Responses

1982 • 202 citations

High concentrations of N-acetylaspartylglutamate (NAAG) selectively activate NMDA receptors on mouse spinal cord neurons in cell culture

1986 • 181 citations

Excitatory synaptic transmission in cultures of rat olfactory bulb

1990 • 175 citations

Inhibition of Cyclic AMP Formation by a Selective Metabotropic Glutamate Receptor Agonist

1992 • 158 citations

Co‐localization of N‐acetyl‐aspartyl‐glutamate in central cholinergic, noradrenergic, and serotonergic neurons

1987 • 99 citations

Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain

1986 • 92 citations

Comparison of Excitatory Amino Acid‐Stimulated Phosphoinositide Hydrolysis and N‐[³H]Acetylaspartylglutamate Binding in Rat Brain: Selective Inhibition of Phosphoinositide Hydrolysis by 2‐Amino‐3‐Phosphonopropionate

1989 • 80 citations

Dipeptides of glutamate and aspartate may be endogenous neuroexcitants in the rat hippocampal slice

1985 • 75 citations

N-Acetylaspartylglutamate catabolism is achieved by an enzyme on the cell surface of neurons and glia

1993 • 73 citations

Ultrastructural localization of N-acetylaspartylglutamate in synaptic vesicles of retinal neurons

1988 • 70 citations

Competitive Inhibition of N‐Acetylated‐α‐Linked Acidic Dipeptidase Activity by N‐Acetyl‐L‐Aspartyl‐β‐Linked L‐Glutamate

1990 • 68 citations

Calcium‐Dependent Evoked Release of N[³H]Acetylaspartylglutamate from the Optic Pathway

1988 • 64 citations

A study of possible excitatory effects of N-acetylaspartylglutamate in different in vivo and in vitro brain preparations

1984 • 64 citations

Release of N‐Acetylaspartylglutamate on Depolarization of Rat Brain Slices

1988 • 63 citations

Calcium-dependent release ofN-acetylaspartylglutamate from retinal neurons upon depolarization

1988 • 56 citations

Specific role of n-acetyl-aspartyl-glutamate in the in vivo regulation of dopamine release from dendrites and nerve terminals of nigrostriatal dopaminergic neurons in the cat

1991 • 51 citations

N‐acetylaspartylglutamate immunoreactivity in neurons of the monkey's visual pathway

1991 • 47 citations

Synaptosomal Transport of Radiolabel from N‐Acetyl‐Aspartyl‐[³H]Glutamate Suggests a Mechanism of Inactivation of an Excitatory Neuropeptide

1986 • 43 citations

Excitatory action of N-acetylaspartylglutamate on Purkinje cells in guinea pig cerebellar slices: an intrasomatic study

1987 • 42 citations

An explanation for the purported excitation of piriform cortical neurons by N-acetyl-L-aspartyl-L-glutamic acid (NAAG).

1989 • 39 citations

Localization and Synaptic Release of N‐acetylaspartyl‐glutamate in the Chick Retina and Optic Tectum

1991 • 39 citations

Electrophysiological and pharmacological actions of N-acetylaspartylglutamate intracellularly studied in cultured chick cerebellar neurons

1987 • 39 citations

Localization and Transport of N‐Acetylaspartylglutamate in Cells of Whole Murine Brain in Primary Culture

1993 • 37 citations

N-acetyl-aspartylglutamate: binding sites and excitatory action in the dorsolateral septum of rats

1987 • 36 citations

The effects of N-acetylaspartylglutamate and distribution of N-acetylaspartylglutamate-like immunoreactivity in the rat somatosensory thalamus

1988 • 32 citations

Uptake, Metabolism, and Release of N‐[³H]‐Acetylaspartylglutamate by the Avian Retina

1992 • 29 citations

Depolarization-evoked release of N-acetyl-L-aspartlyl-L-glutamate from rat brain synaptosomes

1988 • 27 citations

In vitro and in vivo inhibition of N-acetyl-L-aspartyl-L-glutamate catabolism by N-acylated L-glutamate analogs.

1992 • 23 citations

Release of endogenous N-acetylaspartylglutamate (NAAG) and uptake of [3H]NAAG in Guinea pig cerebellar slices

1989 • 12 citations