Circulating concentrations of sFlt1 (soluble fms-like tyrosine kinase 1) in fetal and maternal serum during pre-eclampsia
Data up to Jan 2025
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Abstract
References (25)
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
2003 • 3,707 citations
Circulating angiogenic factors and the risk of preeclampsia*
2004 • 2,591 citations
Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer
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Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome
2002 • 637 citations
Recent Insights into the Pathogenesis of Pre-eclampsia
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Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces Proteinuria
2003 • 519 citations
Birthweight by gestational age in Norway
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Overexpression of the Soluble Vascular Endothelial Growth Factor Receptor in Preeclamptic Patients: Pathophysiological Consequences
2003 • 453 citations
First Trimester Placental Growth Factor and Soluble Fms-Like Tyrosine Kinase 1 and Risk for Preeclampsia
2004 • 450 citations
Longitudinal serum concentrations of placental growth factor: Evidence for abnormal placental angiogenesis in pathologic pregnancies
2003 • 411 citations
Elevated Serum Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR-1) Levels in Women with Preeclampsia
2003 • 396 citations
Pitfalls in the Measurement of Circulating Vascular Endothelial Growth Factor
2001 • 325 citations
Preeclampsia is associated with reduced serum levels of placenta growth factor
1998 • 289 citations
Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies
2001 • 230 citations
Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia
2003 • 220 citations
Elevated serum levels of vascular endothelial growth factor in patients with preeclampsia
1995 • 208 citations
Selective deficit of angiogenic growth factors characterises pregnancies complicated by pre‐eclampsia
1999 • 192 citations
Suppression of serum vascular endothelial growth factor immunoreactivity in normal pregnancy and in pre‐eclampsia
1997 • 158 citations
Maternal plasma levels of vascular endothelial growth factor in normotensive pregnancies and in pregnancies complicated by pre‐eclampsia
1996 • 137 citations
Amniotic fluid–soluble vascular endothelial growth factor receptor-1 in preeclampsia
2000 • 133 citations
Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors.
2001 • 107 citations
Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal–fetal interface in the mouse placenta
2003 • 75 citations
Maternal and Transplacental Effects of Cocaine
1998 • 39 citations
Amniotic Fluid–Soluble Vascular Endothelial Growth Factor Receptor-1 in Preeclampsia
2000 • 33 citations
Angiogenic Factors in Preeclampsia
2017 • 5 citations