DIFFERENTIAL REGULATION BY IL-4 AND IL-10 OF RADIATION-INDUCED IL-6 AND IL-8 PRODUCTION AND ICAM-1 EXPRESSION BY HUMAN ENDOTHELIAL CELLS

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Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

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Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human Monocytes

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Properties and Functions of Interleukin-10

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Interleukin-4 (IL-4) inhibits secretion of IL-1 beta, tumor necrosis factor alpha, and IL-6 by human monocytes

1990 • 438 citations

Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10.

1992 • 412 citations

Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.

1992 • 324 citations

Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13.

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IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor, or IFN-gamma.

1990 • 311 citations

IL-4 acts synergistically with IL-1 beta to promote lymphocyte adhesion to microvascular endothelium by induction of vascular cell adhesion molecule-1.

1990 • 286 citations

IL-4 inhibits the expression of IL-8 from stimulated human monocytes.

1990 • 244 citations

Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells.

1995 • 235 citations

The role of IL-4, IL-10, and TNF-α in the immune suppression induced by ultraviolet radiation

1994 • 228 citations

Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin

1995 • 207 citations

Induction of IL-10 gene expression in human keratinocytes by UVB exposure in vivo and in vitro.

1995 • 175 citations

Interleukin-4 induces the synthesis and secretion of MCP-1/JE by human endothelial cells.

1991 • 165 citations

Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro

1997 • 159 citations

Local Production of Interleukin-4 During Radiation-induced Pneumonitis and Pulmonary Fibrosis in Rats: Macrophages as a Prominent Source of Interleukin-4

1997 • 141 citations

TGF-β1, IL-10 and IL-4 differentially modulate the cytokine-induced expression of IL-6 and IL-8 in human endothelial cells

1996 • 138 citations

Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation

1994 • 138 citations

Role of leukocyte-endothelial cell adhesion in radiation-induced microvascular dysfunction in rats

1995 • 117 citations

The effect of pentoxifylline on early and late radiation injury following fractionated irradiation in C3H mice

1989 • 116 citations

IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury.

1996 • 112 citations

IL-10 inhibits the adhesion of leukocytic cells to IL-1-activated human endothelial cells

1995 • 106 citations

On Radiation Damage to Normal Tissues and its Treatment: II. Anti-inflammatory drugs

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Proinflammatory effects of local abdominal irradiation on rat gastrointestinal tract

1989 • 90 citations

Peripheral Blood Mononuclear Cells Induce Programmed Cell Death in Human Endothelial Cells and May Prevent Repair: Role of Cytokines

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Interleukin-10 induces E-selectin on small and large blood vessel endothelial cells.

1996 • 81 citations

Divergent effects of interleukin‐10 on cytokine production by mononuclear phagocytes and endothelial cells

1993 • 80 citations

Gene Expression of Macrophage Inflammatory Protein-1α from Human Blood Monocytes and Alveolar Macrophages Is Inhibited by Interleukin-4

1993 • 78 citations

Ionizing radiation enhances IL‐6 and IL‐8 production by human endothelial cells

1997 • 75 citations

Interleukin 4 induces interleukin 6 production by endothelial cells: Synergy with interferon‐γ

1991 • 74 citations

Use of steroids to suppress vascular response to radiation

1987 • 65 citations

Interleukin 4 amplifies monocyte chemotactic protein and interleukin 6 production by endothelial cells

1992 • 58 citations

Interleukin-4 and Interleukin-10 Increase Endotoxin-Stimulated Human Umbilical Vein Endothelial Cell Interleukin-8 Release

1995 • 52 citations

Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021

1995 • 51 citations

The Vascular System

1990 • 42 citations

INFLUENCE OF BACTERIAL ENDOTOXIN ON RADIATION-INDUCED ACTIVATION OF HUMAN ENDOTHELIAL CELLS IN VITRO AND IN VIVO

1996 • 42 citations

IL-4 regulates the morphology, cytoskeleton, and proliferation of human umbilical vein endothelial cells: relationship between vimentin and CD23

1993 • 42 citations

Effects of irradiation doses on alterations in cytokine release by monocytes and lymphocytes.

1994 • 39 citations

Contrasting effects of interferon γ and interleukin 4 on responses of human vascular endothelial cells to tumour necrosis factor α

1992 • 34 citations

Current status of clinical development of interleukin-10

1996 • 34 citations

11–4 Decreases IFN‐γ‐Induced Endothelial ICAM‐1 Expression by a Transcriptional Mechanism

1992 • 33 citations

INFLUENCE OF BACTERIAL ENDOTOXIN ON RADIATION-INDUCED ACTIVATION OF HUMAN ENDOTHELIAL CELLS IN VITRO AND IN VIVO

1997 • 23 citations

Rapid neutrophil accumulation and protein oxidation in irradiated rat lungs

1994 • 18 citations