Iontophoretic Delivery of ALA Provides a Quantitative Model for ALA Pharmacokinetics and PpIX Phototoxicity in Human Skin

Photodynamic therapy with endogenous protoporphyrin

1990 • 1,519 citations

Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor.

1976 • 1,430 citations

New trends in photobiology

1992 • 1,194 citations

Photodynamic therapy of non-melanoma malignant tumours of the skin using topical δ-amino levulinic acid sensitization and laser irradiation

1994 • 432 citations

Superficial photodynamic therapy with topical 5-aminolaevulinic acid for superficial primary and secondary skin cancer

1994 • 365 citations

Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid

1993 • 356 citations

Relationship of tumor hypoxia and response to photodynamic treatment in an experimental mouse tumor.

1987 • 346 citations

A portable instrument for quantifying erythema induced by ultraviolet radiation

1984 • 303 citations

Repetitive photodynamic therapy with topical δ-aminolaevulinic acid as an appropriate approach to the routine treatment of superficial non-melanoma skin tumours

1995 • 271 citations

Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid

1993 • 266 citations

PHOTOBLEACHING OF PORPHYRINS USED IN PHOTODYNAMIC THERAPY AND IMPLICATIONS FOR THERAPY

1987 • 265 citations

A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin

1994 • 254 citations

Oxygen dependence of the photosensitizing effect of hematoporphyrin derivative in NHIK 3025 cells.

1985 • 225 citations

NON‐INVASIVE TECHNIQUE FOR OBTAINING FLUORESCENCE EXCITATION AND EMISSION SPECTRA IN VIVO

1986 • 184 citations

DISTRIBUTION OF 5‐AMINOLEVULINIC ACID‐INDUCED PORPHYRINS IN NODULOULCERATIVE BASAL CELL CARCINOMA

1995 • 183 citations

lontophoretic Devices for Drug Delivery.

1986 • 167 citations

Iontophoresis in dermatology

1986 • 157 citations

CELLULAR FLUORESCENCE OF THE ENDOGENOUS PHOTOSENSITIZER PROTOPORPHYRIN IX FOLLOWING EXPOSURE TO 5‐AMINOLEVULINIC ACID

1995 • 149 citations

Endogenous porphyrin distribution induced by 5-aminolaevulinic acid in the tissue layers of the gastrointestinal tract

1993 • 147 citations

Topical application of 5-aminolevulinic acid, DMSO and EDTA: protoporphyrin IX accumulation in skin and tumours of mice

1995 • 140 citations

PENETRATION POTENCY OF TOPICAL APPLIED δ‐AMINOLEVULINIC ACID FOR PHOTODYNAMIC THERAPY OF BASAL CELL CARCINOMA *

1994 • 138 citations

DRUG and LIGHT DOSE DEPENDENCE OF PHOTODYNAMIC THERAPY: A STUDY OF TUMOR and NORMAL TISSUE RESPONSE

1987 • 125 citations

In vivo fluorescence kinetics and photodynamic therapy using 5-aminolaevulinic acid-induced porphyrin: increased damage after multiple irradiations

1994 • 124 citations

Increased penetration of nonelectrolytes into mouse skin during iontophoretic water transport (iontohydrokinesis).

1980 • 106 citations

Effects of photodynamic therapy with topical application of 5-aminolevulinic acid on normal skin of hairless guinea pigs

1992 • 103 citations

Iontophoretic delivery of a series of tripeptides across the skin in vitro.

1991 • 100 citations

SUBCELLULAR LOCALIZATION OF AND PHOTOSENSITIZATION BY PROTOPORPHYRIN IX IN HUMAN KERATINOCYTES AND FIBROBLASTS CULTIVATED WITH 5‐AMINOLEVULINIC ACID

1995 • 76 citations

Kinetics of Endogenous Protoporphyrin IX Induction by Aminolevulinic Acid: Preliminary Studies in the Bladder

1994 • 42 citations

Photodynamic therapy of experimental colonic tumours with 5-aminolevulinic-acid-induced endogenous porphyrins

1994 • 15 citations

Photodynamische Diagnostik und Therapie von Neoplasien der Gesichtshaut nach topischer Applikation von 5-Aminolävulinsäure

1995 • 15 citations