The suppressive effect of gelatin-conjugated superoxide dismutase on disease development and severity of collagen-induced arthritis in mice

Enzyme-linked immunosorbent assay (ELISA) quantitative assay of immunoglobulin G

1971 • 3,630 citations

Autoimmunity to type II collagen an experimental model of arthritis.

1977 • 1,599 citations

Free Radicals and Inflammation: Protection of Synovial Fluid by Superoxide Dismutase

1974 • 1,109 citations

Immunisation against heterologous type II collagen induces arthritis in mice

1980 • 1,025 citations

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

1992 • 1,002 citations

Free radicals and inflammation: superoxide-dependent activation of a neutrophil chemotactic factor in plasma.

1980 • 628 citations

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

1983 • 561 citations

Free radicals, lipids and protein degradation

1986 • 556 citations

Oxygen Radicals in Influenza-Induced Pathogenesis and Treatment with Pyran Polymer-Conjugated SOD

1989 • 420 citations

Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin

1972 • 420 citations

Serum transfer of collagen-induced arthritis in mice.

1983 • 414 citations

Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.

1990 • 336 citations

Oxidants, inflammation, and anti‐inflammatory drugs

1988 • 267 citations

Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity.

1988 • 264 citations

Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation.

1985 • 175 citations

Immunochemistry of Collagens and Procollagens

1976 • 173 citations

Capacity of Mycobacterial Wax D and its Subfractions to Induce Adjuvant Arthritis in Rats

1969 • 150 citations

Hydroxyl radical production by H2O2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from the oxidatively damaged enzyme.

1992 • 134 citations

Isolation of T cell line capable of protecting mice against collagen-induced arthritis.

1988 • 115 citations

Superoxide production by polymorphonuclear leucocytes in rheumatoid arthritis and osteoarthritis: in vivo inhibition by the antirheumatic drug piroxicam due to interference with the activation of the NADPH-oxidase.

1986 • 109 citations

Neutrophils isolated from the synovial fluid of patients with rheumatoid arthritis: priming and activation in vivo.

1991 • 99 citations

Depolymerisation products of hyaluronic acid after exposure to oxygen-derived free radicals.

1985 • 97 citations

Oxidative damage to lipids within the inflamed human joint provides evidence of radical-mediated hypoxic-reperfusion injury

1991 • 69 citations

Chain breaking antioxidant status in rheumatoid arthritis: clinical and laboratory correlates.

1991 • 69 citations

Suppression of Reaginic Antibodies with Modified Allergens

1978 • 61 citations

The biological activity of the synthetic polyanion, pyran copolymer (diveema, MVE, 46015) and the heterocyclic bis DEAE fluorenone derivative, tilorone and congeners: Clinical and laboratory effect of these agents as modulators of host resistance

1981 • 38 citations

Suppression of Reaginic Antibodies with Modified Allergens

1981 • 34 citations

Suppression of reaginic antibodies with modified allergens. IV. Induction of suppressor T cells by conjugates of polyethylene glycol (PEG) and monomethoxy PEG with ovalbumin.

1981 • 34 citations

The role of neutrophils in type II collagen-induced arthritis in rats.

1984 • 32 citations

Improvement of Pharmacological Properties of Protein-Drugs by Tailoring with Synthetic Polymers

1988 • 30 citations

Monocyte dependent excited oxygen radical generation in rheumatoid arthritis: inhibition by gold sodium thiomalate.

1983 • 29 citations

CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF SUCCINYL NEOCARZINOSTATIN

1974 • 20 citations

Monocyte superoxide anion production in rheumatoid arthritis: preliminary evidence for enhanced rates of superoxide anion production by monocytes from patients receiving penicillamine, sodium aurothiomalate and corticosteroids.

1984 • 15 citations

Monocyte Metabolic Activation in Patients with Rheumatoid Arthritis

1979 • 14 citations

Delayed type hypersensitivity (DTH) to type II collagen (CII) in DBA-1 mice.

1986 • 7 citations