Differential Profiles of Binding of a Radiolabeled Agonist and Antagonist at a Glycine Recognition Domain on the N‐ Methyl‐D‐Aspartate Receptor lonophore Complex in Rat Brain

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1992 • 805 citations

A Glycine Site Associated with N‐Methyl‐<scp>d</scp>‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists

1989 • 723 citations

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

1988 • 517 citations

Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.

1988 • 495 citations

3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine.

1987 • 335 citations

Cloning, expression and modulation of a mouse NMDA receptor subunit

1992 • 291 citations

Light microscopic autoradiographic localisation of [3H]glycine and [3H]strychnine binding sites in rat brain

1986 • 247 citations

Determination of the Equilibrium Dissociation Constants and Number of Glycine Binding Sites in Several Areas of the Rat Central Nervous System, Using a Sodium‐Independent System

1981 • 169 citations

Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain

1987 • 160 citations

Ifenprodil and SL 82.0715 are antagonists at the polyamine site of the N-methyl-D-aspartate (NMDA) receptor

1989 • 154 citations

Quinolinic acid: regional variations in neuronal sensitivity

1983 • 145 citations

Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel

1987 • 140 citations

7‐クロルキヌレン酸はN‐メチル‐D‐アスパラギン酸受容体複合体のグリシン調節部位での選択的きっ抗物質である

1988 • 130 citations

Structural requirements for activation of the glycine receptor that modulates the N-methyl-D-aspartate operated ion channel

1988 • 120 citations

1‐Aminocyclopropane Carboxylic Acid: A Potent and Selective Ligand for the Glycine Modulatory Site of the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Complex

1989 • 120 citations

Characterization df a [³H]Glycine Recognition Site as a Modulatory Site of the N‐Methyl‐D‐Aspartate Receptor Complex

1989 • 106 citations

Quinoxaline derivatives are high-affinity antagonists of the NMDA receptor-associated glycine sites

1989 • 105 citations

Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site.

1990 • 102 citations

Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors.

1989 • 89 citations

Spermine enhances binding to the glycine site associated with the N-methyl-D-aspartate receptor complex.

1989 • 86 citations

Microbial methodological artifacts in [3H]glutamate receptor binding assays

1989 • 83 citations

Glutathione-induced inhibition of Na+-independent and -dependent bindings of L-[3H] glutamate in rat brain

1986 • 82 citations

Polyamines regulate glycine interaction with the N‐methyl‐<scp>D</scp>‐aspartate receptor

1990 • 80 citations

Disclosure by triton X-100 of NMDA-sensitive [3H]glutamate binding sites in brain synaptic membranes

1988 • 78 citations

Characterization of the binding of [3H]L-689,560, an antagonist for the glycine site on the N-methyl-D-aspartate receptor, to rat brain membranes.

1992 • 73 citations

[3H]5,7-Dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites

1991 • 66 citations

Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques.

1991 • 66 citations

Strychnine-insensitive binding of [3H]glycine to synaptic membranes in rat brain, treated with triton X-100

1989 • 60 citations

Characterization of Na+-dependent binding sites of [3H]glutamate in synaptic membranes from rat brain

1986 • 59 citations

Labeling of NMDA receptor channels by [3H]MK-801 in brain synaptic membranes treated with Triton X-100

1989 • 56 citations

[3H]glycine binding is modulated by Mg2+ and other ligands of the NMDA receptor-cation channel complex

1988 • 53 citations

Support for Radiolabeling of a Glycine Recognition Domain on the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Ionophore Complex by 5,7‐[³H]Dichlorokynurenate in Rat Brain

1993 • 51 citations

Molecular target size analyses of the NMDA-receptor complex in rat cortex

1989 • 51 citations

1-Aminocyclopropane-1-carboxylic acid (ACC) mimics the effects of glycine on the NMDA receptor ion channel

1988 • 50 citations

The Glycine Site of the N‐Methyl‐D‐Aspartate Receptor Channel: Differences Between the Binding of HA‐966 and of 7‐Chlorokynurenic Acid

1990 • 46 citations

Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate

1991 • 45 citations

5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors

1990 • 42 citations

Characterization of spermidine-dependent [3H](+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801) binding in brain synaptic membranes treated with Triton X-100.

1991 • 40 citations

A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties

1989 • 39 citations

Thiokynurenates: a new group of antagonists of the glycine moduiatory site of the NMBA receptor

1991 • 37 citations

High-affinity glycine binding sites in rat CNS: Regional variation and strychnine sensitivity

1978 • 36 citations

Interaction of Strychnine‐Insensitive Glycine Binding with MK‐801 Binding in Brain Synaptic Membranes

1990 • 27 citations

N-Methyl-d-aspartate-sensitive [3H]glutamate binding sites in brain synaptic membranes treated with Triton X-100

1989 • 26 citations

Temperature-independent binding of[3H](±)-3-(2-car☐ypiperazin-4-yl)propyl-1-phosphonic acid in brain synaptic membranes treated by Triton X-100

1990 • 25 citations

6,7‐Dichloroquinoxaline‐2,3‐Dione is a Competitive Antagonist Specific to Strychnine‐Insensitive [³H]Glycine Binding Sites on the N‐Methyl‐D‐Aspartate Receptor Complex

1990 • 22 citations

Abolition of the NMDA-mediated responses by a specific glycine antagonist, 6,7-dichloroquinoxaline-2,3-dione (DCQX)

1989 • 21 citations

Comparative studies on binding of 3 different ligands to theN-methyl-d-aspartate recognition domain in brain synaptic membranes treated with Triton X-100

1993 • 20 citations

Identification and characterization of specific binding sites of [3H]spermidine in synaptic membranes of rat brain

1991 • 18 citations

[³H]Thienylcyclohexylpiperidine Binding Activity in Brain Synaptic Membranes Treated with Triton X‐100

1990 • 16 citations

Further Evidence for Multiple Forms of an N‐Methyl‐<scp>d</scp>‐Aspartate Recognition Domain in Rat Brain Using Membrane Binding Techniques

1993 • 15 citations

Differential effects of SH-reactive agents on [3H](±)-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonate and [3H]glutamate binding in brain synaptic membranes treated with triton X-100

1991 • 13 citations

A modulating role of mercurials-sensitive sulfhydryl groups in synaptic GABA receptor binding

1982 • 12 citations

[³H] 5,7-Dichlorokynurenic Acid, a High Affinity Ligand for the NMDA Receptor Glycine Regulatory Site

1991 • 8 citations

Studies on [3H]Glutamate Binding in Nervous Tissues. What are the Pitfalls?

1991 • 2 citations