Recent structural solutions for antibody neutralization of viruses

Isolation of a Common Receptor for Coxsackie B Viruses and Adenoviruses 2 and 5

1997 • 3,081 citations

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

1981 • 2,490 citations

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

1993 • 2,182 citations

Structure of influenza haemagglutinin at the pH of membrane fusion

1994 • 1,546 citations

Structure of a human common cold virus and functional relationship to other picornaviruses

1985 • 1,419 citations

The major human rhinovirus receptor is ICAM-1

1989 • 1,134 citations

The three-dimensional structure of foot-and-mouth disease virus at 2.9 Å resolution

1989 • 854 citations

A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses

1989 • 825 citations

Structural Basis of Immune Recognition of Influenza Virus Hemagglutinin

1990 • 554 citations

Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization.

1994 • 418 citations

Antibodies to the vitronectin receptor (integrin alpha V beta 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells

1995 • 303 citations

Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery

1995 • 292 citations

Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells

1993 • 276 citations

The structure and antigenicity of a type C foot-and-mouth disease virus

1994 • 258 citations

Structure of influenza virus haemagglutinin complexed with a neutralizing antibody

1995 • 235 citations

The Canyon Hypothesis

1989 • 226 citations

Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon

1996 • 200 citations

Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus

1990 • 198 citations

Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction.

1995 • 194 citations

Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization

1997 • 184 citations

Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody

1993 • 137 citations

Structure of a neutralizing antibody bound bivalently to human rhinovirus 2.

1996 • 128 citations

Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop

1997 • 105 citations

Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host

1995 • 91 citations

Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope

1995 • 78 citations

Induced Pocket to Accommodate the Cell Attachment Arg-Gly-Asp Motif in a Neutralizing Antibody Against Foot-and-Mouth-Disease Virus

1996 • 52 citations

Electron microscopy of influenza haemagglutinin-monoclonal antibody complexes

1983 • 46 citations

Direct Imaging of Interactions between an Icosahedral Virus and Conjugate Fab Fragments by Cryoelectron Microscopy and X-Ray Crystallography

1994 • 43 citations

Strategy for producing new foot-and-mouth disease vaccines that display complex epitopes

1996 • 9 citations