PROTEIN KINASE ACTIVITY AND THE NATURAL OCCURRENCE OF 2‐5A IN INTERFERON‐TREATED EMC VIRUS‐INFECTED L‐CELLS

pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

1978 • 787 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts

1978 • 435 citations

Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis

1976 • 435 citations

2-5A synthetase: assay, distribution and variation with growth or hormone status

1979 • 260 citations

Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA.

1978 • 216 citations

Concerning the mechanism of action of interferon.

1966 • 210 citations

Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.

1978 • 194 citations

Inhibition of protein synthesis by 2′–5′ linked adenine oligonucleotides in intact cells

1978 • 182 citations

Increased sensitivity of cell-free protein synthesis to double-stranded RNA after interferon treatment

1974 • 179 citations

The (2′‐5′)Oligoadenylate (pppA2′‐5′A2′‐5′A) Synthetase and Protein Kinase(s) from Interferon‐Treated Cells

1979 • 173 citations

Increased nuclease activity in cells treated with pppA2'p5'A2'p5' A.

1979 • 155 citations

Mechanism of Interferon Action: Inhibition of Viral Messenger Ribonucleic Acid Translation in L-Cell Extracts

1972 • 154 citations

Interferon inhibits Viral Protein Synthesis in L Cells infected with Vaccinia Virus

1972 • 145 citations

Synthesis and Breakdown of pppA2′p5′A2′p5′A and Transient Inhibition of Protein Synthesis in Extracts from Interferon‐Treated and Control Cells

1978 • 140 citations

Activation of a nuclease by pppA2′p5′ A2′p5′ A in intact cells

1979 • 108 citations

Oligonucleotide inhibitor of protein synthesis made in extracts of interferon-treated chick embryo cells: Comparison with the mouse low molecular weight inhibitor

1978 • 107 citations

Metabolic stability of 2′ 5′oligo (A) and activity of 2′ 5′oligo (A)-dependent endonuclease in extracts of interferon-treated and control HeLa cells

1979 • 103 citations

Enzymic Synthesis, Characterisation and Nuclear‐Magnetic‐Resonance Spectra of pppA2′p5′A2′p5′A and Related Oligonucleotides: Comparison with Chemically Synthesised Material

1979 • 101 citations

Specific protein phosphorylation in interferon-treated uninfected and virus-infected mouse L929 cells: enhancement by double-stranded RNA

1979 • 56 citations

The respective roles of the protein kinase and pppA2′ p5′ A2′ p5′ A-activated endonuclease in the inhibition of protein synthesis by double stranded RNA in rabbit reticulocyte lysates

1979 • 55 citations

Location of enhanced ribonuclease activity and of a phosphoprotein kinase in interferon-treated mengovirus-infected cells

1979 • 17 citations

INDUCTION, PURIFICATION, AND PROPERTIES OF 2′5′-OLIGOADENYLATE SYNTHETASE

1979 • 13 citations