Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

1993 • 2,237 citations

Molecular Biology of Prion Diseases

1991 • 1,978 citations

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1992 • 1,632 citations

Scrapie prion protein contains a phosphatidylinositol glycolipid

1987 • 1,104 citations

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication

1990 • 874 citations

Cell-free formation of protease-resistant prion protein

1994 • 872 citations

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

1991 • 871 citations

Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome

1989 • 834 citations

Prion protein is necessary for normal synaptic function

1994 • 802 citations

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins

1987 • 757 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

1991 • 543 citations

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.

1990 • 510 citations

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.

1994 • 308 citations

Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity.

1993 • 307 citations

The prion protein gene: a role in mouse embryogenesis?

1992 • 274 citations

Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C

1990 • 263 citations

Prion dementia without characteristic pathology

1990 • 230 citations

Rapid detection of Creutzfeldt‐Jakob disease and scrapie prion proteins

1990 • 217 citations

The prion's progress

1991 • 128 citations

A prion-like protein from chicken brain copurifies with an acetylcholine receptor-inducing activity.

1991 • 118 citations

Iatrogenic transmission of Creutzfeldt-Jakob disease

1989 • 105 citations

Synaptic degeneration is the primary neuropathological feature in prion disease

1993 • 100 citations

Localization of the mRNA for a chicken prion protein by in situ hybridization.

1993 • 90 citations

Prion Diseases of Humans and Animals

2000 • 86 citations

Conservation of the cellular gene encoding the scrapie prion protein

1986 • 85 citations

Motor neurone disease and animal models

1994 • 58 citations

Length-Tension Relationship of Urinary Bladder Strips from Streptozotocin-Diabetic Rats

1990 • 54 citations

Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones

1994 • 33 citations

Normal development of nerve—muscle synapses in mice lacking the prion protein gene

1992 • 27 citations

Prion diseases

1992 • 18 citations