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Effects of the level of mRNA expression on biophysical properties, sensitivity to neurotoxins, and regulation of the brain delayed-rectifier K+ channel Kv1.2

Data up to Jan 2025

Published1992
Citations65
References34

Total Citations Per Year

Abstract

References (34)

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Determination of the subunit stoichiometry of a voltage-activated potassium channel

1991 • 925 citations

Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

1989 • 765 citations

Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 • 752 citations

Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

1992 • 708 citations

Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

1991 • 688 citations

Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

1990 • 461 citations

An essential ‘set’ of K+ channels conserved in flies, mice and humans

1992 • 304 citations

Differential expression of K+ channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures

1992 • 222 citations

An emerging pharmacology of peptide toxins targeted against potassium channels

1988 • 218 citations

Purification and subunit structure of a putative K+-channel protein identified by its binding properties for dendrotoxin I.

1988 • 201 citations

How might the diversity of potassium channels be generated?

1990 • 191 citations

Cloning and tissue‐specific expression of the brain calcium channel β‐subunit

1991 • 186 citations

Homology and analogy in transmembrane channel design: lessons from synaptic membrane proteins

1990 • 159 citations

Members of the RCK potassium channel family are differentially expressed in the rat nervous system.

1990 • 155 citations

Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.

1992 • 134 citations

Peptide Toxins and Potassium Channels

1990 • 126 citations

Long-term potentiation of synaptic transmission in the hippocampus induced by a bee venom peptide

1987 • 100 citations

Alpha-dendrotoxin acceptor from bovine brain is a K+ channel protein. Evidence from the N-terminal sequence of its larger subunit

1990 • 98 citations

Dendrotoxin-binding brain membrane protein displays a potassium channel activity that is stimulated by both cAMP-dependent and endogenous phosphorylations

1989 • 94 citations

Purification and pharmacological characterization of peptide toxins from the black mamba (Dendroaspis polylepis) venom

1990 • 68 citations

Different types of K+ channel current are generated by different levels of a single mRNA.

1992 • 65 citations

Charybdotoxin blocks dendrotoxin‐sensitive voltage‐activated K+ channels

1989 • 60 citations

Families of potassium channel genes in mammals: Toward an understanding of the molecular basis of potassium channel diversity

1991 • 58 citations

Charybdotoxin is a new member of the potassium ion channel toxin family that includes dendrotoxin I and mast cell degranulating peptide

1989 • 54 citations

The presence in pig brain of an endogenous equivalent of apamin, the bee venom peptide that specifically blocks Ca2+-dependent K+ channels.

1984 • 54 citations

Inhibition of .beta.-bungarotoxin binding to brain membranes by mast cell degranulating peptide, toxin I, and ethylene glycol bis(.beta.-aminoethyl ether)-N,N,N',N'-tetraacetic acid

1988 • 52 citations

Analogies and differences in the mode of action and properties of binding sites (localization and mutual interactions) of two K+ channel toxins, MCD peptide and dendrotoxin I

1989 • 52 citations

Existence of different populations of the dendrotoxin I binding protein associated with neuronal K+ channels

1988 • 48 citations

The brain response to the bee venom peptide MCD. Activation and desentization of a hippocampal target

1987 • 46 citations

Molecular aspects of neuronal voltage‐dependent K+ channels

1991 • 33 citations

High affinity receptors for the bee venom MCD peptide. Quantitative autoradiographic localization at different stages of brain development and relationship with MCD neurotoxicity

1988 • 32 citations

Level of expression controls modes of gating of a K+ channel

1992 • 25 citations

Out on a limb

1991 • 1 citations

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Effects of the level of mRNA expression on biophysical properties, sensitivity to… (1992) – Biochemistry | Metascience Observatory Explorer