Protein stability parameters measured by hydrogen exchange

[14]Determination and analysis of urea and guanidine hydrochloride denaturation curves

1986 • 2,265 citations

Primary structure effects on peptide group hydrogen exchange

1993 • 1,851 citations

A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study

1974 • 1,384 citations

Hydrogen exchange and structural dynamics of proteins and nucleic acids

1983 • 1,329 citations

Hydrogen Exchange in Proteins

1966 • 1,115 citations

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

1991 • 882 citations

DENATURED STATES OF PROTEINS

1991 • 870 citations

Protein interactions with urea and guanidinium chloride

1992 • 623 citations

The barriers in protein folding

1994 • 436 citations

Isotope effects in peptide group hydrogen exchange

1993 • 365 citations

The Solubility of Amino Acids, Diglycine, and Triglycine in Aqueous Guanidine Hydrochloride Solutions

1970 • 352 citations

THE THERMODYNAMIC STABILITY OF PROTEINS

1987 • 338 citations

pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1

1990 • 331 citations

A test of the linear extrapolation of unfolding free energy changes over an extended denaturant concentration range

1992 • 314 citations

Hydrogen exchange and the dynamic structure of proteins

1982 • 308 citations

Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. II. Dependence on denaturant concentration at 25°

1969 • 269 citations

Stable submolecular folding units in a non-compact form of cytochrome c

1991 • 220 citations

Structural Characterization of the FK506 Binding Protein Unfolded in Urea and Guanidine Hydrochloride

1994 • 177 citations

Guanidinium Chloride Induction of Partial Unfolding in Amide Proton Exchange in RNase A

1993 • 176 citations

Thermodynamic characterization of cytochrome c at low pH

1992 • 153 citations

Guanidine hydrochloride and acid denaturation of horse, cow, and Candida krusei cytochromes c

1974 • 145 citations

Amide proton exchange in proteins by EX1 kinetics: studies of the basic pancreatic trypsin inhibitor at variable p2H and temperature

1985 • 131 citations

Structural interpretation of the amide proton exchange in the basic pancreatic trypsin inhibitor and related proteins

1979 • 120 citations

Protein internal flexibility and global stability: Effect of urea on hydrogen exchange rates of bovine pancreatic trypsin inhibitor

1993 • 118 citations

[22] Structural characterization of protein folding intermediates by proton magnetic resonance and hydrogen exchange

1989 • 105 citations

HYDROGEN EXCHANGE STUDIES OF DNA STRUCTURE

1965 • 101 citations

Ferricytochrome c chain folding measured by the energy transfer of tryptophan 59 to the heme group

1976 • 97 citations

MEASUREMENT OF STRUCTURAL AND FREE ENERGY CHANGES IN HEMOGLOBIN BY HYDROGEN EXCHANGE METHODS

1975 • 96 citations

Hydrogen Exchange Measurement of the Free Energy of Structural and Allosteric Change in Hemoglobin

1992 • 92 citations

NMR assignments as a basis for structural characterization of denatured states of globular proteins

1994 • 91 citations

Mechanisms of hydrogen exchange in proteins from NMR studies of individual tryptophan indole amine hydrogens in lysozyme

1982 • 86 citations

Hydrogen exchange in unligated and ligated staphylococcal nuclease

1993 • 77 citations

Microcalorimetric studies of conformational transitions of ferricytochrome c in acidic solution

1989 • 73 citations

Studies of Hydrogen Exchange in Proteins

1971 • 66 citations

Formation of a Hydrophobic Cluster in Denatured Bovine Pancreatic Trypsin Inhibitor

1994 • 62 citations

Studies of Hydrogen Exchange in Proteins

1968 • 52 citations

Studies of .beta.-sheet structure in lysozyme by proton nuclear magnetic resonance. Assignments and analysis of spin-spin coupling constants

1982 • 51 citations

Local breathing and global unfolding in hydrogen exchange of barnase and its relationship to protein folding pathways.

1993 • 48 citations

Studies of hydrogen exchange in proteins. VI. Urea effects on ribonuclease exchange kinetics leading to a general model for hydrogen exchange from folded proteins.

1971 • 48 citations

HELIX‐RANDOM COIL TRANSFORMATIONS IN DEUTERATED MACROMOLECULES*

1960 • 41 citations

Symposium on Peptide Chemistry

1964 • 38 citations

A novel application of nuclear Overhauser enhancement (NOE) in proteins: Analysis of correlated events in the exchange of internal labile protons

1980 • 26 citations

Comparison of amide proton exchange in reduced and oxidizedRhodobacter capsulatus cytochrome c2: A1H−15N NMR study

1991 • 25 citations

Nonnative isomers of proline-93 and -114 predominate in heat-unfolded ribonuclease A

1990 • 19 citations

Proline Isomerization and Protein Folding

1990 • 11 citations