An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The Regulation of Rabbit Skeletal Muscle Contraction

1971 • 4,491 citations

Organization, Chemistry, and Assembly of the Cytoskeletal Apparatus of the Intestinal Brush Border

1985 • 525 citations

The gapped duplex DNA approach to oligonucleotide-directed mutation construction

1984 • 511 citations

Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain

1986 • 477 citations

Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

1980 • 444 citations

Microtubules containing detyrosinated tubulin are less dynamic.

1987 • 429 citations

INFECTION OF HUMAN AND SIMIAN TISSUE CULTURES WITH ROUS SARCOMA VIRUS

1964 • 354 citations

Thymosin β4 and Fx, an actin-sequestering peptide, are indistinguishable

1991 • 352 citations

Identification and organization of the components in the isolated microvillus cytoskeleton.

1979 • 303 citations

Modular organization of actin crosslinking proteins

1991 • 282 citations

Villin: The major microfilament-associated protein of the intestinal microvillus

1979 • 270 citations

Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells?

1985 • 193 citations

Alterations in the phenotype of plant cells studied by NH ₂ -terminal amino acid-sequence analysis of proteins electroblotted from two-dimensional gel-separated total extracts

1987 • 178 citations

Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells.

1980 • 176 citations

Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains.

1988 • 170 citations

F actin assembly modulated by villin: Ca++-dependent nucleation and capping of the barbed end

1981 • 167 citations

Actin-binding proteins

1990 • 164 citations

Villin induces microvilli growth and actin redistribution in transfected fibroblasts

1989 • 163 citations

Regulation of actin polymerization by villin, a 95,000 dalton cytoskeletal component of intestinal brush borders

1980 • 149 citations

Functional comparison of villin and gelsolin. Effects of Ca2+, KCl, and polyphosphoinositides.

1988 • 145 citations

Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli.

1983 • 136 citations

Villin sequence and peptide map identify six homologous domains.

1988 • 136 citations

Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity.

1988 • 129 citations

The F-actin capping proteins of Physarum polycephalum: cap42(a) is very similar, if not identical, to fragmin and is structurally and functionally very homologous to gelsolin; cap42(b) is Physarum actin.

1987 • 116 citations

Demonstration of at least two different actin-binding sites in villin, a calcium-regulated modulator of F-actin organization.

1981 • 115 citations

On the mechanism of actin monomer-polymer subunit exchange at steady state.

1983 • 112 citations

Calcium control of microfilaments: uncoupling of the F-actin-severing and -bundling activity of villin by limited proteolysis in vitro.

1981 • 102 citations

Effect of villin on the kinetics of actin polymerization

1984 • 95 citations

From the structure to the function of villin, an actin‐binding protein of the brush border

1990 • 86 citations

Nucleation of polar actin filament assembly by a positively charged surface.

1979 • 66 citations

Microinjection of villin into cultured cells induces rapid and long-lasting changes in cell morphology but does not inhibit cytokinesis, cell motility, or membrane ruffling.

1990 • 64 citations

[33] Use of immunocytochemical techniques in studying the biogenesis of cell surfaces in polarized epithelia

1983 • 59 citations

An actin‐interacting heptapeptide in the cofilin sequence

1989 • 59 citations

Immunolocalization of the 110,000 molecular weight cytoskeletal protein of intestinal microvilli

1981 • 58 citations

Demonstration of three distinct calcium-binding sites in villin, a modulator of actin assembly.

1983 • 55 citations

High-level transient expression of influenza virus proteins from a series of SV40 late and early replacement vectors

1988 • 47 citations

In vivo analysis of functional domains from villin and gelsolin.

1992 • 46 citations

Ligand-induced conformational changes in villin, a calcium-controlled actin-modulating protein.

1983 • 43 citations

Identification of the site important for the actin-activated MgATPase activity of myosin subfragment-1

1991 • 34 citations

Actin polymerization promoted by a heptapeptide, an analog of the actin-binding S site on myosin head.

1991 • 14 citations