Markedly increased circulating pyridoxal-5'-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism.

Sensory Neuropathy from Pyridoxine Abuse

1983 • 695 citations

Vitamin B6 Metabolism in Chronic Alcohol Abuse

1974 • 286 citations

A simple enzymic assay for pyridoxal phosphate

1970 • 191 citations

Pyridoxal 5'-phosphate in plasma: source, protein-binding, and cellular transport.

1974 • 156 citations

Adult hypophosphatasia. Clinical, laboratory, and genetic investigation of a large kindred with review of the literature.

1979 • 141 citations

A versatile cation-exchange procedure for measuring the seven major forms of vitamin B6 in biological samples

1983 • 132 citations

Adult hypophosphatasia with chondrocalcinosis and arthropathy

1982 • 100 citations

Enzyme replacement therapy for infantile hypophosphatasia attempted by intravenous infusions of alkaline phosphatase-rich Paget plasma: Results in three additional patients

1984 • 85 citations

Vitamin B6 deficiency in chronic liver disease--evidence for increased degradation of pyridoxal-5'-phosphate.

1977 • 81 citations

Characterization of the pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate hydrolase activity in rat liver. Identity with alkaline phosphatase.

1975 • 80 citations

Blood and urine levels of vitamin B6 in the mother and fetus before and after loading of the mother with vitamin B6

1970 • 74 citations

Pantothenic Acid, Vitamin B6 and Vitamin B12 in Foods

1970 • 57 citations

Vitamin B6 deficiency in cancer patients

1977 • 57 citations

Hydrolysis of pyridoxal-5'-phosphate in plasma in conditions with raised alkaline phosphate.

1980 • 56 citations

Adult hypophosphatasia without apparent skeletal disease: “odontohypophosphatasia“ in four heterozygote members of a family

1984 • 53 citations

Alkaline Phosphatase Deficiency in Cultured Skin Fibroblasts from Patients with Hypophosphatasia: Comparison of the Infantile, Childhood, and Adult Forms*

1983 • 34 citations

Urinary 4-Pyridoxic Acid, Urinary Vitamin B-6 and Plasma Pyridoxal Phosphate as Measures of Vitamin B-6 Status and Dietary Intake in Adults

1981 • 31 citations

Clearance and metabolism of plasma pyridoxal 5'-phosphate in the dog.

1984 • 27 citations

Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults

1983 • 27 citations

Pyridoxal 5?-phosphate: a possible physiological substrate for alkaline phosphatase in human neutrophils

1983 • 19 citations

Pyridoxal phosphate in lymphocytes, polymorphonuclear leukocytes, and platelets in Down’s syndrome

1974 • 13 citations

Structural analysis of human alkaline phosphatase.

1984 • 13 citations

Vitamin B6: an overview.

1983 • 12 citations

Bone growth changes in pyridoxine‐deficient rats

1975 • 9 citations

Levels and subcellular localisation of pyridoxal and pyridoxal phosphate in human polymorphonuclear leukocytes and their relationship to alkaline phosphatase activity

1983 • 4 citations