Human placental 3β-hydroxy-5-ene-steroid dehydrogenase and steroid 5 → 4-ene-isomerase: Purification from microsomes, substrate kinetics, and inhibition by product steroids

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

The determination of enzyme inhibitor constants

1953 • 4,050 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors (Short Communication)

1974 • 908 citations

Utilization of Oxygen and Reduced Nicotinamide Adenine Dinucleotide Phosphate by Human Placental Microsomes during Aromatization of Androstenedione

1974 • 693 citations

Biological Aromatization of Steroids

1959 • 596 citations

SIGNIFICANT FALL IN PROGESTERONE AND RISE IN $OElig;STRADIOL LEVELS IN HUMAN PERIPHERAL PLASMA BEFORE ONSET OF LABOUR

1974 • 180 citations

The Preparation and Properties of Crystalline Δ5-3-Ketosteroid Isomerase

1962 • 107 citations

The ‘See‐Saw’ Theory of Parturition

1977 • 101 citations

Analytical and Preparative Polyacrylamide Gel Electrophoresis

1976 • 82 citations

Human placental Δ5-3β hydroxysteroid dehydrogenase activity (Δ5-33 HSDH): Intracellular distribution, kinetic properties, retroinhibition and influence of membrane delipidation

1975 • 77 citations

Human Placental 17β-Estradiol Dehydrogenase

1970 • 69 citations

Purification and characterization of rat adrenal 3β-hydroxysteroid dehydrogenase with steroid 5-ene-4-ene-isomerase

1986 • 57 citations

Purification and properties of testicular 3β-hydroxy-5-ene-steroid dehydrogenase and 5-ene-4-ene isomerase

1986 • 52 citations

Distribution of 3-β-hydroxysteroid dehydrogenase and Δ5-3-oxosteroid isomerase in homogenate fractions of human term placenta

1965 • 51 citations

Concentration-dependent association of delta5-3-ketosteroid isomerase of Pseudomonas testosteroni.

1975 • 47 citations

INHIBITION OF PLACENTAL 3β-HYDROXY-STEROID DEHYDROGENASE BY NATURALLY OCCURRING STEROIDS. A POTENTIAL MECHANISM REGULATING OESTROGEN SYNTHESIS FROM UNCONJUGATED PRECURSORS

1975 • 43 citations

Kinetic analysis of the placental microsomal 3β-hydroxysteroid dehydrogenase activity

1979 • 22 citations

Modification of the kinetic properties of 5-ene, 3β-hydroxysteroid dehydrogenase of human placental microsomes by hydrogen peroxide and 2-mercaptoethanol

1978 • 20 citations

Preparation of highly purified 3α- and 3β-hydroxysteroid dehydrogenases from Pseudomonas sp.

1979 • 19 citations

Steroid specificity of human placental 5-ene-3β-hydroxysteroid oxidoreductase

1979 • 18 citations

Substrate and nucleotide specificity of placental microsomal 3β-hydroxysteroid dehydrogenase

1981 • 18 citations

Purification and Kinetic Properties of 3β-Hydroxysteroid Dehydrogenase from Bovine Adrenocortical Microsomes1

1985 • 16 citations

3β-Hydroxysteroid dehydrogenase in human placental microsomes and mitochondria: Co-solubilization of androstene and pregnene activities

1986 • 15 citations

The purification and characterization of delta 5-3-ketosteroid isomerase from Pseudomonas putida, a cysteine-containing isomerase.

1980 • 14 citations

Microsomal 5-ane-3β-hydroxysteroid oxidoreductase from pubertal rat leydig cells: Partial purification and characterization

1983 • 14 citations

Kinetic studies of the applicability of the common site concept to the 3β-hydroxysteroid dehydrogenase: 5-ene-3-ketosteroid isomerase activities of human placental microsomes

1982 • 8 citations

Activation of Δ5-3-ketosteroid isomerase of bovine adrenal microsomes by serum albumins

1979 • 7 citations

A modified digitonin-precipitation radioassay for 3β-hydroxy-Δ5-steroid dehydrogenase

1987 • 6 citations