Tumor cell antigenicity, host immunity, and cancer metastasis

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

The pathogenesis of cancer metastasis

1980 • 1,750 citations

Metastasis Results from Preexisting Variant Cells Within a Malignant Tumor

1977 • 1,422 citations

Tumor heterogeneity and the biology of cancer invasion and metastasis.

1978 • 833 citations

The Biology of Cancer Invasion and Metastasis

1978 • 819 citations

Antigenicity of Murine Skin Tumors Induced by Ultraviolet Light2

1974 • 484 citations

A critique of the evidence for active host defence against cancer, based on personal studies of 27 murine tumours of spontaneous origin

1976 • 478 citations

The Immune Reaction as a Stimulator of Tumor Growth

1972 • 403 citations

Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis.

1977 • 400 citations

Immunologic Parameters of Ultraviolet Carcinogenesis 2

1976 • 334 citations

Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor.

1978 • 281 citations

Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin.

1978 • 248 citations

Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts.

1976 • 239 citations

Specificity of arrest, survival, and growth of selected metastatic variant cell lines.

1978 • 203 citations

Latency, histology, and antigenicity of tumors induced by ultraviolet light in three inbred mouse strains.

1977 • 202 citations

Further Studies on the Tumor-Specific Suppressor Cells Induced by Ultraviolet Radiation

1978 • 189 citations

An Immunostimulation Theory of Tumor Development

1971 • 186 citations

Characterization in vivo and in vitro of tumor cells selected for resistance to syngeneic lymphocyte-mediated cytotoxicity.

1976 • 175 citations

In Vivo Immune Responses of Mice During Carcinogenesis by Ultraviolet Irradiation 2

1977 • 134 citations

Immunological escape mechanism in spontaneously metastasizing mammary tumors.

1975 • 131 citations

Analysis of Antigenic Heterogeneity Within Individual 3-Methylcholanthrene-Induced Mouse Sarcomas<xref ref-type="fn" rid="FN2">2</xref>

1970 • 126 citations

Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis

1977 • 125 citations

Implications of immunological heterogeneity of tumours

1979 • 117 citations

Immune stimulation-inhibition of experimental cancer metastasis.

1974 • 115 citations

Immunostimulation of the Lymphodependent Phase of Neoplastic Growth

1977 • 113 citations

Differences in Cell Surface Antigens of Tumor Metastases and Those of the Local Tumor2

1979 • 108 citations

MODIFICATION OF IMMUNOLOGICAL POTENTIAL BY ULTRAVIOLET RADIATION

1977 • 90 citations

Influence of immune status on the metastasis of three murine fibrosarcomas of different immunogenicities.

1979 • 89 citations

Altered antigenicity in spontaneous pulmonary metastases from an antigenic murine sarcoma.

1972 • 89 citations

Macrophages and cancer

1978 • 86 citations

Immunologically-mediated restraint of latent tumour metastases

1975 • 78 citations

Isolation of immunogenic tumour cells by cell-affinity chromatography

1976 • 73 citations

Antigenic differences between primary methylcholanthrene‐induced rat sarcomas and post‐surgical recurrences

1977 • 72 citations

Heterogeneity and variability of artificial lung colony-forming ability among clones from mouse fibrosarcoma.

1978 • 70 citations

FURTHER CHARACTERIZATION OF IMMUNOLOGICAL UNRESPONSIVENESS INDUCED IN MICE BY ULTRAVIOLET RADIATION GROWTH AND INDUCTION OF NONULTRAVIOLET-INDUCED TUMORS IN ULTRAVIOLET-IRRADIATED MICE

1979 • 59 citations

Antigenic differences among osteogenic sarcoma tumor cells taken from different locations in human tumors.

1977 • 58 citations

Back to the drawing board—the need for more realistic model systems for immunotherapy

1977 • 48 citations

Immunotherapy of Cancer in Animals: Models or Muddles?4

1976 • 36 citations

Role of Immunosurveillance against Chemically Induced Rat Tumors

1976 • 35 citations

A survey of the growth characteristics of and the host reactions to one hundred C3H/He mammary carcinomas.

1978 • 34 citations

In Vitro Reactivity of Macrophages and Lymphocytes From Ultraviolet-Irradiated Mice 2

1977 • 29 citations

Enhanced experimental metastasis of ultraviolet light-induced fibrosarcomas in ultraviolet light-irradiated syngeneic mice.

1980 • 29 citations

Effect of Antilymphocyte Serum on Parameters of Growth of MCA-induced Tumours

1969 • 29 citations

Relevant animal models for tumor immunotherapy

1976 • 27 citations

Enhancement of Metastases by L-Asparaginase in a Mouse Tumour System

1971 • 20 citations

Influence of serial transplantation on the immunological-clinical correlates of BALB/cfC3H mouse mammary tumors.

1978 • 20 citations

Abrogation of the anti-metastatic activity of C. parvum by antilymphocyte serum

1976 • 19 citations

Host immunity in experimental metastasis

1978 • 12 citations

ROLE OF THYMUS IN SKIN AND TUMOR TRANSPLANTATION IN THE RAT.

1965 • 8 citations