A galanin-mastoparan chimeric peptide activates the Na+,K+-ATPase and reverses its inhibition by ouabain

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Fundamentals of Enzyme Kinetics

1979 • 2,137 citations

G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides

1990 • 428 citations

Galanin--a neuroendocrine peptide.

1993 • 251 citations

Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom.

1983 • 224 citations

Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins.

1990 • 169 citations

M-15: high-affinity chimeric peptide that blocks the neuronal actions of galanin in the hippocampus, locus coeruleus, and spinal cord.

1991 • 158 citations

Insulin and glucagon stimulation of (Na+-K+)-ATPase transport activity in isolated rat hepatocytes.

1981 • 150 citations

Linear and cyclic N‐terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor

1991 • 121 citations

The energy coupled exchange of Na⁺ for K⁺ across the cell membrane

1990 • 114 citations

Fundamentals of enzyme kinetics

1980 • 100 citations

Membrane interactions of amphiphilic polypeptides mastoparan, melittin, polymyxin B, and cardiotoxin. Differential inhibition of protein kinase C, Ca2+/calmodulin-dependent protein kinase II and synaptosomal membrane Na,K-ATPase, and Na+ pump and differentiation of HL60 cells.

1991 • 95 citations

A wasp venom mastoparan‐induced polyphosphoinositide breakdown in rat peritoneal mast cells

1985 • 78 citations

Insulin stimulates both the alpha 1 and the alpha 2 isoforms of the rat adipocyte (Na+,K+) ATPase. Two mechanisms of stimulation

1991 • 63 citations

Novel peptide inhibitor (SPAI) of Na+, K+-ATPase from porcine intestine

1989 • 52 citations

Assay for Galanin Receptor

1991 • 35 citations

Effects of the amphiphilic peptides mastoparan and adenoregulin on receptor binding, G proteins, phosphoinositide breakdown, cyclic AMP generation, and calcium influx

1994 • 25 citations

Membrane interactions of mastoparan analogues related to their differential effects on protein kinase C, Na,K‐ATPase and HL60 cells

1992 • 18 citations

Activation of Na,K‐ATPase by an endogenous peptide, PEC‐60

1994 • 16 citations

Bradykinin stimulation of oxidative metabolism in renal cortical tubules from rabbit. Possible role of arachidonic acid.

1985 • 10 citations

Effects of N- and C-terminal fragments of substance P on ATPase and monoamine oxidase activities in rat brain

1990 • 7 citations

Mastoparan inhibits rat renal NAK-ATPase activity

1990 • 4 citations

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