Defective assembly of the B‐cell receptor chains accounts for its low expression in B‐chronic lymphocytic leukaemia

The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL.

1994 • 788 citations

The Release of Intact Oligosaccharides from Specific Glycoproteins by Endo-β-N-acetylglucosaminidase H

1974 • 499 citations

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

1994 • 430 citations

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.

1994 • 340 citations

Regulation of an Early Developmental Checkpoint in the B Cell Pathway by Igβ

1996 • 294 citations

Attachment of terminal N-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the golgi stack

1985 • 291 citations

Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia.

1989 • 290 citations

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly.

1992 • 259 citations

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

2000 • 241 citations

Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta.

1993 • 237 citations

Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to production of natural autoantibodies

1990 • 222 citations

B-chronic lymphocytic leukemia: a malignancy of anti-self B cells

1996 • 212 citations

Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin)

1993 • 203 citations

Chronic lymphocytic leukemic (CLL) cells secrete multispecific autoantibodies

1988 • 179 citations

CD79a: a novel marker for B-cell neoplasms in routinely processed tissue samples

1995 • 176 citations

Mutations of immunoglobulin transmembrane and cytoplasmic domains: Effects on intracellular signaling and antigen presentation

1990 • 154 citations

Prognostic Significance of the Cell Cycle Inhibitor p27Kip1 in Chronic B-Cell Lymphocytic Leukemia

1998 • 149 citations

Prognostic Significance of the Cell Cycle Inhibitor p27Kip1 in Chronic B-Cell Lymphocytic Leukemia

1998 • 126 citations

Comparison of Normal and CLL Lymphocyte Surface Ig Determinants Using Peroxidase-labeled Antibodies. I. Detection and Quantitation of Light Chain Determinants

1974 • 119 citations

An Alternatively Spliced Form of CD79b Gene May Account for Altered B-Cell Receptor Expression in B-Chronic Lymphocytic Leukemia

1999 • 111 citations

Inhibition of Intracellular Transport of B Cell Antigen Receptor Complexes by Kaposi's Sarcoma–Associated Herpesvirus K1

2000 • 103 citations

Antigen receptor nonresponsiveness in chronic lymphocytic leukemia B cells

1995 • 98 citations

Expression of the immunoglobulin-associated protein B29 in B cell disorders with the monoclonal antibody SN8 (CD79b).

1996 • 95 citations

Aberrations of the B-Cell Receptor B29 (CD79b) Gene in Chronic Lymphocytic Leukemia

1997 • 92 citations

A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes.

1994 • 73 citations

Molecular mechanisms that control expression of the B lymphocyte antigen receptor complex.

1995 • 50 citations

Normal Syk protein level but abnormal tyrosine phosphorylation in B-CLL cells

1997 • 50 citations

Alternative splicing of CD79a ( ) and CD79b ( ) RNA transcripts in human B cells

1995 • 44 citations

Transcription and protein expression of mb-1 and B29 genes in human hematopoietic malignancies and cell lines.

1993 • 41 citations

Analysis of the B-Cell Receptor B29 (CD79b) Gene in Familial Chronic Lymphocytic Leukemia

1999 • 36 citations

Individual cell-by-cell quantitation of lymphocyte surface membrane Ig in normal and CLL lymphocyte and during ontogeny of mouse B lymphocytes by immunoperoxidase assay

1980 • 34 citations

The complete nucleotide sequence of a human immunoglobulin genomic Cμgene

1989 • 26 citations

The novel variants of mb-1 and B29 transcripts generated by alternative mRNA splicing

1995 • 26 citations

Aberrant glycosylation of L-selectin on the lymphocytes of chronic lymphocytic leukemia.

1993 • 18 citations

Roles of calnexin and Ig-alpha beta interactions with membrane Igs in the surface expression of the B cell antigen receptor of the IgM and IgD classes.

1997 • 18 citations

Aberrant Trafficking of the B Cell Receptor Ig-αβ Subunit in a B Lymphoma Cell Line

2000 • 8 citations

Alternative Splicing of CD79a (Igα) and CD79b (Igß Transcripts in Human B-CLL Cells

1999 • 7 citations