Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins.

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

1985 • 1,650 citations

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.

1988 • 626 citations

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

1988 • 540 citations

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

1988 • 514 citations

Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients

1985 • 448 citations

HTLV-III-neutralizing antibodies in patients with AIDS and AIDS-related complex

1985 • 427 citations

Neutralization of the AIDS Retrovirus by Antibodies to a Recombinant Envelope Glycoprotein

1986 • 362 citations

Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteins

1987 • 301 citations

Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies

1991 • 249 citations

Induction of anti-HIV neutralizing antibodies by synthetic peptides.

1986 • 237 citations

An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies

1989 • 222 citations

Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: Receptor modulation and differentiation induced by phorbol ester

1987 • 187 citations

Anti-GP 120 Antibodies from HIV Seropositive Individuals Mediate Broadly Reactive Anti-HIV ADCC

1987 • 131 citations

Neutralization of diverse HIV-1 strains by monoclonal antibodies raised against a gp41 synthetic peptide

1988 • 128 citations

Two immunodominant domains of gp41 bind antibodies which enhance human immunodeficiency virus type 1 infection in vitro

1991 • 120 citations

Human immunodeficiency virus type 1-neutralizing monoclonal antibodies which react with p17 core protein: characterization and epitope mapping

1989 • 119 citations

A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope.

1987 • 119 citations

Human immunodeficiency virus type 1 p24 production and antigenic variation in tissue culture of isolates with various growth characteristics

1989 • 112 citations

Persistent infection of chimpanzees with human immunodeficiency virus: serological responses and properties of reisolated viruses

1987 • 111 citations

Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp 120

1990 • 90 citations

Structure and function of the HIV envelope

1989 • 72 citations

A monoclonal antibody to human immunodeficiency virus type 1 which mediates cellular cytotoxicity and neutralization

1990 • 61 citations

Identification of amino acids in the V3 region of gp120 critical for virus neutralization by human HIV-1-specific antibodies.

1991 • 25 citations

Production and Characterization of a Human Monoclonal Antibody, Reactive with a Conserved Epitope on gp41 of Human Immunodeficiency Virus Type I

1990 • 21 citations

Antigenicity of linear B-cell epitopes in the C1, V1, and V3 region of HIV-1 gp 120.

1989 • 14 citations

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