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An Enzymatic Mechanism for the Antithrombotic and Antihemostatic Actions of Aspirin

Data up to Jan 2025

Published1974
Citations107
References20

Total Citations Per Year

Abstract

References (20)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

The aggregation of blood platelets

1963 • 2,125 citations

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

1971 • 1,535 citations

Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

1973 • 640 citations

IMPAIRED PLATELET/CONNECTIVE-TISSUE REACTION IN MAN AFTER ASPIRIN INGESTION

1967 • 376 citations

Stimulation and Blockade of Prostaglandin Biosynthesis

1971 • 286 citations

THE EFFECT OF ACETYLSALICYLIC ACID ON PLATELET FUNCTION

1968 • 279 citations

Platelet Aggregation induced by Arachidonic Acid is accompanied by Release of Potential Inflammatory Mediators distinct from PGE2 and PGF2

1973 • 227 citations

Effect of acetylsalicylic acid, other nonsteroidal anti-inflammatory agents, and dipyridamole on human blood platelets.

1970 • 216 citations

Formation of Prostaglandins during the Aggregation of Human Blood Platelets

1973 • 180 citations

Inhibition of prostaglandin biosynthesis by eicosa-5,8,11,14-tetraynoic acid

1970 • 132 citations

Duration of inhibition of platelet prostaglandin formation and aggregation by ingested aspirin or indomethacin

1973 • 127 citations

Isolation of a chemical trigger for thrombosis

1974 • 103 citations

Effect of Prostaglandin E2 and Aspirin on the Secondary Aggregation of Human Platelets

1972 • 101 citations

A new potential mediator of arterial thrombosis whose biosynthesis is inhibited by aspirin

1973 • 81 citations

Protection by Aspirin against Experimentally Induced Arterial Thrombosis in Dogs

1971 • 47 citations

Effect of eight prostaglandins on platelet aggregation

1970 • 45 citations

Acetylenic Analog of Arachidonate That Acts Like Aspirin on Platelets

1974 • 43 citations

Effect of aspirin, sodium salicylate, and acetaminophen on bleeding.

1971 • 32 citations

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An Enzymatic Mechanism for the Antithrombotic and Antihemostatic Actions of Aspirin (1974) – Science | Metascience Observatory Explorer