β-Amyloid peptides induce degeneration of cultured rat microglia

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1989 • 3,477 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1992 • 1,602 citations

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1993 • 1,422 citations

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

Cytology & cellular pathology of the nervous system

1965 • 1,037 citations

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

1992 • 982 citations

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease

1989 • 904 citations

In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity

1991 • 833 citations

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR

1987 • 806 citations

Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease

1988 • 702 citations

Ameboid microglia as effectors of inflammation in the central nervous system

1987 • 477 citations

β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

1992 • 291 citations

Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain

1989 • 281 citations

β-Amyloid protein promotes neuritic branching in hippocampal cultures

1990 • 188 citations

Elastase-type proteases on the surface of human blood monocytes: possible role in amyloid formation.

1980 • 135 citations

β-Amyloid induces neuritic dystrophy in vitro

1992 • 132 citations

Fibronectin and laminin regulate thein vitro differentiation of microglial cells

1991 • 98 citations

Voltage‐gated currents expressed by rat microglia in culture

1992 • 81 citations

Impaired Kupffer cell function precedes development of secondary amyloidosis.

1985 • 79 citations

Antibodies in the cerebrospinal fluid of some Alzheimer's disease patients recognize amoeboid microglial cells in the developing rat central nervous system

1991 • 37 citations