TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

Innate Immune Recognition

2002 • 8,157 citations

Approaching the Asymptote? Evolution and Revolution in Immunology

1989 • 3,079 citations

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

2006 • 1,104 citations

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf

2006 • 1,097 citations

A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

2003 • 610 citations

Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling

2006 • 572 citations

Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells

2006 • 436 citations

The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells

2003 • 399 citations

Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response

2001 • 393 citations

Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1β are differentially regulated in human blood mononuclear cells and mouse spleen cells

1999 • 368 citations

Aluminum Hydroxide Adjuvants Activate Caspase-1 and Induce IL-1β and IL-18 Release

2007 • 308 citations

Induction of adaptive immunity by flagellin does not require robust activation of innate immunity

2009 • 74 citations

TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage

2010 • 74 citations

Salmonella typhimuriumtranscytoses flagellin via an SPI2-mediated vesicular transport pathway

2004 • 55 citations