Neonatal dopamine lesion in the rat results in enhanced adenylate cyclase activity without altering dopamine receptor binding or dopamine- and adenosine 3??5?-monophosphate-regulated phosphoprotein (DARPP-32) immunoreactivity

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

The rat brain: A stereotaxic atlas of the forebrain and lower parts of the brain stem

1986 • 4,155 citations

Multiple receptors for dopamine

1979 • 3,739 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

A simple method of reducing the fading of immunofluorescence during microscopy

1981 • 1,907 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Fluorescent Antibody Methods

1969 • 1,549 citations

Adipsia and Aphagia after 6‐Hydroxydopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,271 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in Brain

1977 • 1,017 citations

Opposing roles for D-1 and D-2 dopamine receptors in efflux of cyclic AMP from rat neostriatum

1981 • 917 citations

SCH 23390—The first selective dopamine D-1 antagonist

1983 • 738 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization

1984 • 652 citations

Serotonergic component of neuroleptic receptors

1978 • 621 citations

Dopamine in dendrites of substantia nigra neurons: suggestions for a role in dendritic terminals

1975 • 482 citations

Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines

1974 • 451 citations

Dopamine-Sensitive Adenyl Cyclase: Possible Role in Synaptic Transmission

1971 • 415 citations

Heterogeneity of striatal and limbic dopamine innervation: Highly fluorescent islands in developing and adult rats

1972 • 404 citations

Selective Brain Dopamine Depletion in Developing Rats: An Experimental Model of Minimal Brain Dysfunction

1976 • 400 citations

A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions

1983 • 342 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain

1984 • 303 citations

Organization of Catecholamine Neurons in the Rat Central Nervous System

1978 • 280 citations

Behavioral differences between neonatal and adult 6-hydroxydopamine-treated rats to dopamine agonists: relevance to neurological symptoms in clinical syndromes with reduced brain dopamine.

1984 • 280 citations

Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas

1979 • 271 citations

Studies on the pharmacological properties of dopamine receptors in various areas of the central nervous system.

1978 • 260 citations

The D-1 dopamine receptor antagonist SCH 23390 also interacts potently with brain serotonin (5-HT2) receptors

1986 • 245 citations

Characterization of dopamine receptors mediating inhibition of adenylate cyclase activity in rat striatum.

1985 • 236 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution

1986 • 229 citations

Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity

1974 • 228 citations

[3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors

1981 • 210 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus

1984 • 209 citations

6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.

1987 • 201 citations

Growth and behavioral changes in developing rats treated intracisternally with 6-hydroxydopamine: evidence for involvement of brain dopamine.

1973 • 198 citations

Behavioral evidence for dopaminergic supersensitivity after chronic haloperidol

1974 • 195 citations

Sprouting of serotoninergic afferents into striatum after dopamine‐depleting lesions in infant rats: A retrograde transport and immunocytochemical study

1986 • 188 citations

Paradoxical response to amphetamine in developing rats treated with 6-hydroxydopamine

1976 • 170 citations

Selective lesion of central dopamine or noradrenaline neuron systems in the neonatal rat: motor behavior and monoamine alterations at adult stage

1989 • 153 citations

D-1 dopamine receptors in the rat brain: Autoradiographic localization using [3H]SCH 23390

1985 • 148 citations

Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: functional supersensitivity of D-1 dopamine receptors in neonatally lesioned rats.

1985 • 143 citations

Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rats treated neonatally with 6-hydroxydopamine.

1985 • 140 citations

Age-dependent effects of 6-hydroxydopamine on locomotor activity in the rat

1979 • 137 citations

Ontogeny of dopaminergic D-2 receptors in the rat nervous system: Characterization and detailed autoradiographic mapping with [125I]iodosulpride

1989 • 128 citations

Selective D-1 dopamine receptor increase following chronic treatment with SCH 23390

1985 • 125 citations

Sprouting of striatal serotonin nerve terminals following selective lesions of nigro-striatal dopamine neurons in neonatal rat

1987 • 122 citations

Development of a dopamine- and cyclic adenosine 3':5'-monophosphate- regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation

1987 • 122 citations

Different plasticity changes in D1 and D2 receptors in rat striatal subregions following impairment of dopaminergic transmission

1988 • 116 citations

Supersensitivity in rat caudate nucleus: Effects of 6-hydroxydopamine on the time course of dopamine receptor and cyclic AMP changes

1980 • 113 citations

D-1 receptor supersensitivity in the rat striatum after unilateral 6-hydroxydopamine lesions

1986 • 107 citations

Psychopharmacology of Attention Deficit Disorder: Pharmacokinetic, Neuroendocrine, and Behavioral Measures Following Acute and Chronic Treatment with Methylphenidate

1982 • 104 citations

Behavioral and neurochemical responses to haloperidol and SCH-23390 in rats treated neonatally or as adults with 6-hydroxydopamine.

1987 • 101 citations

Effects ofd-amphetamine and methylphenidate on hyperactivity produced by neonatal 6-hydroxydopamine treatment

1989 • 96 citations

[3H]SCH 23390 binding sites increase after chronic blockade of D-1 dopamine receptors

1985 • 96 citations

The D-1 Dopamine Receptor and the Search for its Functional Role: From Neurochemistry to Behaviour

1987 • 95 citations

Inhibition of inositol phospholipid breakdown by D2 dopamine receptors in dissociated bovine anterior pituitary cells

1985 • 95 citations

Possible involvement of serotonergic neurons in the reduction of locomotor hyperactivity caused by amphetamine in neonatal rats depleted of brain dopamine

1982 • 84 citations

Neonatal 6-hydroxydopamine-induced dopamine depletions: Motor activity and performance in maze learning

1988 • 79 citations

Rats given dopamine-depleting brain lesions as neonates are subsensitive to dopaminergic antagonists as adults.

1985 • 77 citations

Dopamine D-2 auto- and postsynaptic receptors in the nigrostriatal system of the rat brain: localization by quantitative autoradiography with [3H]sulpiride

1987 • 76 citations

Selective attention dysfunctions in adult rats neonatally treated with 6-hydroxydopamine

1978 • 76 citations

Dopaminergic supersensitivity induced by denervation and chronic receptor blockade is additive

1982 • 75 citations

The effect of long-term penfluridol treatment on the sensitivity of the dopamine receptors in the nucleus accumbens and in the corpus striatum

1975 • 65 citations

Characterization of binding of3H-SCH 23390 to dopamine D-1 receptors. Correlation to other D-1 and D-2 measures and effect of selective lesions

1987 • 65 citations

Repeated reserpine administration up-regulates the transduction mechanisms of D1 receptors without changing the density of [3H]SCH 23390 binding

1989 • 61 citations

Studies on brain monoamine and neuropeptide systems after neonatal intracerebroventricular 6‐hydroxydopamine treatment

1990 • 60 citations

Dopamine binding following prolonged haloperidol pretreament

1978 • 59 citations

Dopamine D2 receptor stimulation decreases the inositol trisphosphate level of rat striatal slices

1987 • 51 citations

Impaired acquisition of an operant response in young rats depleted of brain dopamine in neonatal life

1983 • 46 citations

Time course of MPTP-induced degeneration of the nigrostriatal dopamine system in C57 BL/6 mice

1988 • 45 citations

In vivo studies of dopamine receptor ontogeny

1982 • 40 citations

Lack of change in striatal DARPP-32 levels following nigrostriatal dopaminergic lesions in animals and in parkinsonian syndromes in man

1990 • 26 citations

Chapter 13 DARPP-32, a dopamine-regulated phosphoprotein

1986 • 23 citations

Impaired striatal dopamine receptor development: differential D-1 regulation in adults

1988 • 19 citations

Immunohistochemical analysis of the effects of cysteamine on somatostatin-like immunoreactivity in the rat central nervous system

1987 • 15 citations

Quantitation of noradrenaline nerve density in mouse iris by computer‐assisted image analysis

1986 • 7 citations

Quantitation of Nerve Terminal Networks of Transmitter-Identified Neurons After Selective Neurotoxic Lesions

1985 • 6 citations

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