Proglumide has access to brain and antagonizes the central satiety effect of cholecystokinin octapeptide in the dog

Cholecystokinin decreases food intake in rats.

1973 • 1,454 citations

New peptide in the vertebrate CNS reacting with antigastrin antibodies

1975 • 749 citations

Immunochemical evidence of cholecystokinin-like peptides in brain

1976 • 676 citations

Isolation, structure and biological activity of two cholecystokinin octapeptides from sheep brain

1978 • 426 citations

Cholecystokinin Octapeptide: Continuous Picomole Injections Into the Cerebral Ventricles of Sheep Suppress Feeding

1979 • 334 citations

Potentiation of Opiate Analgesia and Apparent Reversal of Morphine Tolerance by Proglumide

1984 • 269 citations

Rapid appearance of intraventricularly administered neuropeptides in the peripheral circulation

1982 • 224 citations

Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide

1985 • 156 citations

Neuronal Cholecystokinin: One or Multiple Transmitters?

1985 • 155 citations

Proglumide: Selective Antagonism of Excitatory Effects of Cholecystokinin in Central Nervous System

1983 • 154 citations

Cholecystokinin antagonists selectively potentiate analgesia induced by endogenous opiates

1985 • 136 citations

New glutaramic acid derivatives with potent competitive and specific cholecystokinin-antagonistic activity.

1985 • 115 citations

Operant feeding and drinking in pigs following intracerebroventricular injection of synthetic cholecystokinin octapeptide

1981 • 84 citations

Eating, drinking and temperature responses to intracerebroventricular cholecystokinin in the chick

1982 • 83 citations

Antagonists of central and peripheral behavioral actions of cholecystokinin octapeptide.

1986 • 70 citations

Differentiation of central and peripheral cholecystokinin receptors by new glutaramic acid derivatives with cholecystokinin-antagonistic activity.

1986 • 67 citations

Potentiation of Systemic Morphine Analgesia in Humans by Proglumide, a Cholecystokinin Antagonist

1985 • 61 citations

The role of appetite in the control of body weight

1937 • 54 citations

Blocking of cholecystokinin octapeptide behavioral effects by proglumide

1984 • 42 citations

Further Studies on the Specificity of Proglumide as a Selective Cholecystokinin Antagonist in the Central Nervous Systema

1985 • 38 citations

Activation of central nervous system cholecystokinin receptors stimulates respiration in the cat.

1983 • 32 citations

Characterization of cholecystokinin receptor sites in guinea-pig cortical membranes using [125I]Bolton Hunter-cholecystokinin octapeptide.

1985 • 31 citations

The role of cholecystokinin octapeptide in the central control of food intake in the dog

1987 • 28 citations

The role of some central catecholamine systems in cholecystokinin-induced satiety

1984 • 26 citations

The function and structure of canine arachnoid villi

1962 • 24 citations

Do antagonists of pancreatic cholecystokinin receptors interact with central nervous system cholecystokinin receptors?

1985 • 19 citations