Recognition of nonpeptide antigens by T cells

Tuberculosis: Commentary on a Reemergent Killer

1992 • 1,400 citations

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens

1995 • 751 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

1995 • 672 citations

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.

1995 • 603 citations

Lymphocytes bearing antigen-specific γδ T-cell receptors accumulate in human infectious disease lesions

1989 • 592 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire.

1990 • 510 citations

CDR3 length in antigen-specific immune receptors.

1994 • 503 citations

Stimulation of a major subset of lymphocytes expressing T cell receptor γδ by an antigen derived from mycobacterium tuberculosis

1989 • 491 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

Activation of γδ T Cells in the Primary Immune Response to Mycobacterium tuberculosis

1989 • 463 citations

Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen

1993 • 426 citations

Human γδ+ T cells respond to mycobacterial heat-shock protein

1989 • 417 citations

The nature of major histocompatibility complex recognition by γδ T cells

1994 • 407 citations

A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice.

1992 • 393 citations

The CD1 Family: A Third Lineage of Antigen-Presenting Molecules

1995 • 389 citations

Nonpeptide ligands for human gamma delta T cells.

1994 • 373 citations

A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein.

1990 • 331 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

Primary responses of human T cells to mycobacteria: a frequent set of γ/δ T cells are stimulated by protease‐resistant ligands

1990 • 243 citations

Protective role of γ/δ T cells and α/β T cells in tuberculosis

1995 • 219 citations

Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice.

1994 • 207 citations

Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells.

1991 • 201 citations

Immune protection and control of inflammatory tissue necrosis by gamma delta T cells.

1994 • 189 citations

CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production.

1995 • 184 citations

Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands.

1995 • 177 citations

Human Vγ9‐Vδ2 cells are stimulated in a crossreactive fashion by a variety of phosphorylated metabolites

1995 • 168 citations

Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell.

1994 • 164 citations

T Lymphocytes in Human Tuberculosis

1992 • 164 citations

Increased γδ T cells in acute Plasmodium falciparum malaria

1990 • 163 citations

Sequential appearance of γ/δ‐ and α/β‐bearing T cells in the peritoneal cavity during an i.p. infection with Listeria monocytogenes

1990 • 162 citations

Predominant activation and expansion of V gamma 9-bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection.

1992 • 154 citations

Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection.

1993 • 144 citations

γδ T cell-induced nitric oxide production enhances resistance to mucosal candidiasis

1995 • 134 citations

Early appearing gamma/delta-bearing T cells during infection with Calmétte Guérin bacillus.

1991 • 133 citations

Close correlation between Daudi and mycobacterial antigen recognition by human gamma delta T cells and expression of V9JPC1 gamma/V2DJC delta-encoded T cell receptors.

1993 • 131 citations

Contribution of α/β and γ/δ T lymphocytes to immunity against Mycobacterium bovis Bacillus Calmette Guérin: studies with T cell receptor‐deficient mutant mice

1995 • 128 citations

TCR usage and functional capabilities of human gamma delta T cells at birth.

1994 • 128 citations

Lymphocytes bearing the γδ T cell receptor in acute Brucella melitensis infection

1993 • 125 citations

Transient increase in circulating gamma/delta T cells during Plasmodium vivax malarial paroxysms.

1994 • 114 citations

A predominance of the T cell receptor V gamma 2/V delta 2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition.

1991 • 113 citations

Inhibition of Plasmodium falciparum in vitro by human gamma delta T cells.

1994 • 111 citations

T-Lymphocytes with γδ + Vδ2+ Antigen Receptors Are Present in Increased Proportions in a Fraction of Patients with Tuberculosis or with Sarcoidosis

1993 • 105 citations

Phosphate is essential for stimulation of Vγ9Vδ2 T lymphocytes by mycobacterial low molecular weight ligand

1994 • 100 citations

Lymphocytes bearing the gamma delta T-cell receptor in acute toxoplasmosis.

1992 • 98 citations

Induction of gamma/delta T cells in murine salmonellosis by an avirulent but not by a virulent strain of Salmonella choleraesuis.

1992 • 98 citations

A murine CD4-, CD8- T cell receptor-gamma delta T lymphocyte clone specific for herpes simplex virus glycoprotein I.

1992 • 89 citations

Gamma interferon and interleukin 2, but not interleukin 4, are detectable in gamma/delta T-cell cultures after activation with bacteria

1992 • 87 citations

A lectin-binding, protease-resistant mycobacterial ligand specifically activates V gamma 9+ human gamma delta T cells.

1992 • 77 citations

Predominant expansion of V gamma 9/V delta 2 T cells in a tularemia patient

1992 • 74 citations

Interactions of human alpha/beta and gamma/delta T lymphocyte subsets in shear flow with E-selectin and P-selectin.

1996 • 72 citations

The T cell receptors of human gamma delta T cells reactive to Mycobacterium tuberculosis are encoded by specific V genes but diverse V-J junctions.

1991 • 65 citations

Intercellular interactions and cytokine responsiveness of peritoneal alpha/beta and gamma/delta T cells from Listeria-infected mice: synergistic effects of interleukin 1 and 7 on gamma/delta T cells.

1993 • 63 citations

Mouse T lymphocytes that express a gamma delta T-cell antigen receptor contribute to resistance to Salmonella infection in vivo

1994 • 61 citations

Spontaneous resistance to acute T-cell leukaemias in TCRVγ1.1Jγ4Cγ4 transgenic mice

1995 • 40 citations

Phenotypic characterization of CD4-/alpha beta TCR+ and gamma delta TCR+ T cells with a transendothelial migratory capacity.

1994 • 37 citations

Stimulation of TCR V gamma 3 cells by gram-negative bacteria.

1995 • 34 citations

Different appearance of gamma delta T cells during salmonellosis between Ityr and Itys mice.

1993 • 29 citations

Early appearance of T cell receptor αβ⁺ CD4⁻ CD8⁻ T cells with a skewed variable region repertoire after infection with Listeria monocytogenes

1995 • 22 citations

The appearance and role of γδ T cells in the peritoneal cavity and liver during primary infection with Listeria monocytogenes in rats

1992 • 16 citations