Antibodies to proteinase 3 increase adhesion of neutrophils to human endothelial cells

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

AUTOANTIBODIES AGAINST NEUTROPHILS AND MONOCYTES: TOOL FOR DIAGNOSIS AND MARKER OF DISEASE ACTIVITY IN WEGENER'S GRANULOMATOSIS

1985 • 1,914 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro.

1990 • 1,214 citations

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 • 1,079 citations

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

THE ROLE OF ENDOTHELIAL CELLS IN INFLAMMATION

1990 • 808 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Anticytoplasmic Autoantibodies: Their Immunodiagnostic Value in Wegener Granulomatosis

1989 • 733 citations

PROSPECTIVE STUDY OF RADIOIMMUNOASSAY FOR ANTIBODIES AGAINST NEUTROPHIL CYTOPLASM IN DIAGNOSIS OF SYSTEMIC VASCULITIS

1987 • 714 citations

Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters.

1988 • 436 citations

EndoCAM: a novel endothelial cell-cell adhesion molecule.

1990 • 409 citations

Autoantibodies developing to myeloperoxidase and proteinase 3 in systemic vasculitis stimulate neutrophil cytotoxicity toward cultured endothelial cells.

1992 • 280 citations

Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo.

1991 • 256 citations

Binding of Antibodies to the Extractable Nuclear Antigens SS-A/Ro and SS-B/La Is Induced on the Surface of Human Keratinocytes by Ultraviolet Light (UVL): Implications for the Pathogenesis of Photosensitive Cutaneous Lupus

1990 • 244 citations

Treatment of chronic type B hepatitis with recombinant α-interferon induces autoantibodies not specific for autoimmune chronic hepatitis

1989 • 175 citations

Human endothelial cells express proteinase 3, the target antigen of anticytoplasmic antibodies in Wegener's granulomatosis

1993 • 170 citations

Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells.

1990 • 163 citations

Antineutrophil cytoplasmic autoantibodies: a review of the antigens involved, the assays, and the clinical and possible pathogenetic consequences

1993 • 132 citations

Antineutrophil cytoplasmic autoantibodies: a review of the antigens involved, the assays, and the clinical and possible pathogenetic consequences

1993 • 116 citations

Autoantibodies to endothelial cells and neutrophil cytoplasmic antigens in systemic vasculitis

1990 • 112 citations

Association of La and Ro antigens with intracellular structures in HEp-2 carcinoma cells.

1986 • 100 citations

Detection and quantitation of anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis by ELISA using affinity-purified antigen

1988 • 95 citations

An ELISA for the detection of anti-neutrophil cytoplasm antibodies (ANCA)

1990 • 89 citations

A new assay for the measurement of the attachment of neutrophils and other cell types to endothelial cells

1988 • 77 citations

Intercellular adhesion molecule-1 expression in human kidneys with glomerulonephritis.

1991 • 72 citations

Idiopathic and secondary vasculitis: a review.

1989 • 68 citations

Certain Polyclonal Antinuclear Antibodies Cross‐React with the Surface Membrane of Human Lymphocytes and Granulocytes

1977 • 46 citations

Human endothelial cells: effect of TNF-alpha on peripheral blood mononuclear cell adhesion.

1991 • 44 citations

Intercellular adhesion molecule-1 expression in human kidneys with glomerulonephritis.

1991 • 42 citations

Neutrophil-endothelial cell binding in neutrophil-mediated tissue injury

1992 • 36 citations

A human renal cancer line as a new antigen source for the detection of antibodies to cytoplasmic and nuclear antigens in sera of patients with Wegener's granulomatosis

1991 • 25 citations

Antibodies to Cathepsin G in Crohn's disease

1992 • 24 citations

A monoclonal Ro‐antibody and the serum of a Ro‐positive patient with subacute cutaneous lupus erythematosus (SCLE) react with basal layers of human epidermis

1988 • 17 citations

In Vitro Production of Anti-Neutrophilocyte-Cytoplasm-Antibodies (Anca) by Epstein-Barr Virus-Transformed B-Cell Lines in Wegener's Granulomatosis

1991 • 10 citations